Patent Assignment
Reel/Frame 008933/0844
Security Interest
Recorded: 1998-01-29
Pages: 65
Assignor
HYBRIDON, INC.
Executed: 1998-01-16
Assignee
SILICON VALLEY BANK
40 WILLIAMS STREET, CAMBRIDGE, MASSACHUSETTS, 02139
Covered Properties
(94)
Method for Sequencing Synthetic Oligonucleotides Containing Non- Phosphodiester Internucleotide Linkages
Patent:
5,403,709 →
Application:
07/958,133 →
Separation of Phosphorothioate Oligonucleotides by Capillary Gel Electrophoresis
Patent:
5,420,265 →
Application:
07/991,466 →
A Substrate Useful for Separating Modified Oligonucleotides
Patent:
5,643,717 →
Application:
08/032,856 →
Method for Detecting Charged Oligonucleotides in Biological Fluids
Patent:
5,506,103 →
Application:
08/153,365 →
Dna Methyltransferase Antisense Oligonucleotides
Patent:
5,578,716 →
Application:
08/161,673 →
Method for Analyzing Oligonucleotide Analogs
Patent:
5,627,277 →
Application:
08/178,660 →
A Mehtod of Sequencing Oligonuclleotides
Patent:
5,525,470 →
Application:
08/187,749 →
Detection of Synthetic Oligonucleotides Extracted from Body Fluids or Tissues
Patent:
5,558,992 →
Application:
08/241,062 →
Oligonucleotides with Anti-Cytomegalovirus Activity
Patent:
5,801,235 →
Application:
08/249,386 →
Oligonucleotides with Anti-Mdr-1 Gene Activity
Patent:
5,866,699 →
Application:
08/276,567 →
Method for Loading Solid Supports for Nucleic Acid Synthesis
Patent:
5,554,744 →
Application:
08/311,156 →
Therapeutic Anti-Hiv Anti-Viral Oligonucleotides and Pharmaceutical Formulations Thereof
Patent:
5,684,147 →
Application:
08/319,823 →
Oligonucleotide Multiple Reporter Precursors
Patent:
5,510,475 →
Application:
08/320,835 →
Ribozyme Analogs Having Rigid Non-Nucleotidic Linkers
Patent:
5,650,502 →
Application:
08/336,526 →
Cyclodextrin Cellular Delivery System for Oligonucleotides
Patent:
5,691,316 →
Application:
08/341,522 →
Stabilized Ribozyme Analogs
Patent:
5,545,729 →
Application:
08/361,687 →
Detection of Synthetic Oligonucleotides Extracted from Body Fluids or Tissues
Patent:
5,693,466 →
Application:
08/368,243 →
Inhibition of Neovasuclarization Using Vegf-Specific Oligonucleotides
Patent:
5,731,294 →
Application:
08/378,860 →
Antisense Oligonucleotides Which Combat Aberrant Splicing and Methods of Using the Same
Patent:
5,665,593 →
Application:
08/379,079 →
Methods for H-Phosphonate Synthesis of Oligonucleotides
Application:
08/382,250 →
Human Vegf-Specific Oligonucleotides
Patent:
5,639,872 →
Application:
08/398,945 →
Thiono Triester Modified Antisense Oligodeoxynucleotide Phosphorothioates
Application:
08/409,169 →
Method for Sequencing Synthetic Oligonucletides Containing Non-Phosphodiester Internucleotide Linkages
Patent:
5,652,103 →
Application:
08/412,913 →
Integrated Oligonucleotides
Patent:
5,739,308 →
Application:
08/418,123 →
Cooperative Oligonucleotides
Patent:
6,372,427 →
Application:
08/420,672 →
Methods for H-Phosphonate Synthesis of Oligonucleotides Using Triphosgene
Patent:
5,639,875 →
Application:
08/430,437 →
Antisense Oligonucleotide Alkylphosphonothioates and Arylphospohonothioates
Patent:
5,929,226 →
Application:
08/436,927 →
Method of Synthesizing Radioisotopically Labeled Oligonucletides by Direct Solid-Phase 5'PHOSPHITYLATION
Patent:
5,631,361 →
Application:
08/447,092 →
Procedure for the Detritylation of Dmt-Oligonucleotides Using "Dowex" Ion-Exchange Resin
Patent:
5,808,042 →
Application:
08/447,760 →
Methods and Compounds for the Stereoselective Enrichment of Oligonucleotide Diastereomers and Oligonucleotides Thereby Produced
Patent:
5,750,674 →
Application:
08/448,131 →
Antisense Oligonucleotides Which Combat Aberrant Splicing and Methods of Using the Same
Patent:
5,627,274 →
Application:
08/453,224 →
Reversal of B/A4 Amyloid Peptide Induced Morphological Changes in Neuronal Cells by Antisense Oligonucleotides
Patent:
5,670,634 →
Application:
08/456,420 →
Method of Detecting Sub-Ppb Levels of Oligonucleotides in Biological Fluids
Patent:
5,637,464 →
Application:
08/465,384 →
Oligonucleotides Specific for Hepatitis B Virus
Patent:
5,856,459 →
Application:
08/468,352 →
Oligonucleotides Specific for Hepatitis C Virus
Application:
08/471,968 →
Hpv-Specific Oligonucleotides
Method of Using Ribozyme Analogs Having Rigid, Non-Nucleotidic Molecular Linkers
Patent:
5,679,555 →
Application:
08/478,940 →
Cyclodextrin Cellular Delivery System for Oligonucleotides
Patent:
5,605,890 →
Application:
08/480,833 →
Cyclodextrin Cellular Delivery System for Oligonucleotides
Patent:
5,616,565 →
Application:
08/480,834 →
Antisense Oligonucleotides Having Tumorigenicity-Inhibiting Activity
Patent:
5,919,772 →
Application:
08/481,876 →
Method of Tritium Labeling Oligonucleotides
Patent:
5,668,262 →
Application:
08/485,112 →
Inhibition of Neovascularization Using Vegf-Specific Oligonucleotides
Patent:
5,801,156 →
Application:
08/501,626 →
Human Vegf-Specific Oligonucleotides
Patent:
5,661,135 →
Application:
08/501,779 →
Human Vegf-Specific Oligonucleotides
Patent:
5,639,736 →
Application:
08/502,185 →
Method of Modulating Gene Expression with Reduced Immunostimulatory Response
Patent:
5,968,909 →
Application:
08/511,536 →
Inverted Chimeric and Hybrid Oligonucleotides
Patent:
5,652,356 →
Application:
08/516,454 →
The 4-Pentenoyl Moiety as a Nucleoside-Amino Protecting Group, Pentenoyl-Protected Nucleotide Synthons, and Related Oligonucleotide Syntheses
Patent:
5,614,622 →
Application:
08/518,921 →
Primary Phosphoramidate Internucleoside Linkages and Oligonucleotides Containing the Same
Patent:
6,140,482 →
Application:
08/519,318 →
Use of Cyclodextrins to Modulate Gene Expression with Reduced Immunostimulatory Response
Patent:
6,667,293 →
Application:
08/527,126 →
Modified Protein Kinase a-Specific Oligonucleotide
Patent:
5,969,117 →
Application:
08/532,979 →
In Situ Preparation of Nucleoside Phosphoramidites and Oligonucleotide Synthesis
Application:
08/539,939 →
Oligonucleotides with Anti-Respiratory Syncytial Virus Activity
Application:
08/544,130 →
Methods for H-Phosphonate Synthesis of Mono- and Oligonucleotides
Patent:
5,705,629 →
Application:
08/546,318 →
Modified Vegf Oligonucleotides
Patent:
5,641,756 →
Application:
08/569,926 →
O- and S-Methylphosphotriester Internucleoside Linkages and Oligonucleotides Containing the Same
Patent:
5,955,599 →
Application:
08/570,390 →
Novel Synthons for Stereoselective Oligonucleotide Synthesis
Application:
08/597,434 →
Base Protecting Groups and Synthons for Oligonucleotide Synthesis
Patent:
6,531,589 →
Application:
08/598,320 →
Synthesis of Oligonucleotides Containing Alkylphosphonate Internucleoside Linkages
Patent:
5,962,674 →
Application:
08/606,915 →
Apparatus and Process for Multi Stage Solid Phase Synthesis of Long Chained Organic Molecules
Patent:
5,807,525 →
Application:
08/608,702 →
Oligonucleotides with Anti-Cytomegalovirus Activity
Application:
08/615,801 →
In Situ Preparation of Nucleoside Phosphoramidites and P-Substituted Phosphonamidites and Synthesis of Oligonucleotides and P-Substituted Oligonucleosides
Application:
08/642,653 →
In Situ Preparation of Nucleoside Phosphoramidites and Oligonucleotide Synthesis
Patent:
6,340,749 →
Application:
08/647,354 →
Branched Oligonucleotides as Pathogen-Inhibitory Agents
Patent:
6,489,464 →
Application:
08/664,786 →
Novel Sulfur Transfer Reagents for Oligonucleotide Synthesis
Application:
08/697,847 →
Oligonucleotides Having Modified Cpg Dinucleosides
Patent:
5,856,462 →
Application:
08/711,568 →
Mixed Backbone Antisense Oligonucleotides Containing 2'-5'- Ribonucleotide- and 3'-5'-Deoxyribonucleotides Segments
Patent:
5,886,165 →
Application:
08/719,970 →
Method of Down-Regulating Gene Expression
Application:
08/758,005 →
Modified Vegf Oligonucleotides for Treatment of Skin Disorders
Patent:
6,306,829 →
Application:
08/761,708 →
Novel Base Protecting Groups and Rapid Process for Oligonucleotide Synthesis
Application:
08/795,193 →
Extremely High Purity Oligonucleotides and Methods of Synthesizing Them Using Dimer Blocks
Patent:
6,087,491 →
Application:
08/827,561 →
Method for Synthesizing 2'-O-Substituted Pyrimidine Nucleosides
Patent:
5,739,314 →
Application:
08/846,124 →
Novel Base Protecting Groups and Rapid Process for Oligonucleotide Synthesis
Patent:
6,509,459 →
Application:
08/846,303 →
Down-Regulation of Gene Expression by Colorectal Administration of Synthetic Oligonucleotides
Application:
08/846,417 →
Novel Sulfur Transfer Reagents for Oligonucleotide Synthesis
Application:
08/846,427 →
Hyperstructure-Forming Carriers
Oligonucleotide Mediated Specific Cytokine Induction and Reduction of Tumor Growth in a Mammal
Patent:
6,426,334 →
Application:
08/848,229 →
Novel Sulfur Transfer Reagents for Oligonucleotide Synthesis
Patent:
6,096,881 →
Application:
08/865,666 →
Inverted Chimeric Oligonucleotides
Patent:
5,973,136 →
Application:
08/886,670 →
Inverted Chimeric and Hybrid Oligonucleotides
Patent:
5,773,601 →
Application:
08/886,860 →
Hpv-Specific Oligonucleotides
Oligonucleotides Speciific for Hepatitis C Virus
Application:
08/887,505 →
Publication:
US 2002/0081577
Novel Sulfurizing Reagent: 3-Aryl-1,2,4-Dithiazoline-5-Ones
Oligonucleotides Specific for Hepatitis B Virus
Patent:
6,984,729 →
Application:
08/901,612 →
MDM2-Specific Antisense Oligonucleotides
Application:
08/916,384 →
Improved Reagents and Process for Synthesis of Oligonucleoside Containing Phosphorodithioate Internucleoside
Patent:
6,117,992 →
Application:
08/920,087 →
Apparatus and Process for Multi-Stage Solid-Phase Synthesis of Long-Chained Organic Molecules
Application:
60/010,165 →
Oligonucleotides Specific for Hepatitis C Virus
Application:
60/021,104 →
Oligonucleotide Prodrugs
Application:
60/024,262 →
Oligonucleotides Specific for the Marorab Operon and Methods of Their Use
Application:
60/038,663 →
Method for Sequencing of Modified Nucleic Acids Using Electrospray Ionization - Fourier Transform Mass Spectrometry
Application:
60/040,717 →
Modified Protein Kinase a Specific Oligonucleotides and Methods of Their Use
Application:
60/040,740 →
Antisense Oligonuclecleotides Specific for Thymidylate Synthase
Application:
60/045,230 →
3' Substituted Oligonucleotides
Application:
60/053,718 →
Novel Detritylation Solvents for Oligonucleotide Synthesis
Application:
60/058,142 →
Related Assignments
(25)
Other recorded transfers of the patents in this record — the chain of ownership.
Assignment of Assignors Interest.
Nov 30, 1992
From: AGRAWAL, SUDHIR; TANG, JIN-YAN
To: HYBRIDON, INC.
Reel/Frame 006350/0275 →
Assignment of Assignors Interest.
Dec 16, 1992
From: COHEN, AHARON S.; VILENCHIK, MARIA
To: HYBRIDON, INC.
Reel/Frame 006397/0720 →
Assignment of Assignor's Interest
Mar 16, 1993
From: COHEN, AHARON S.; VILENCHIK, MARIA
To: HYDRIDON, INC.
Reel/Frame 006557/0670 →
Assignment of Assignor's Interest
Dec 20, 1993
From: COHEN, AHARON S.; BOURQUE, ANDRE
To: HYBRIDON, INC.
Reel/Frame 006801/0940 →
Assignment of Assignor's Interest
Jan 7, 1994
From: COHEN, AHARON S.; BOURQUE, ANDRE; VILENCHIK, MARIA
To: HYBRIDON, INC.
Reel/Frame 006929/0537 →
Assignment of Assignor's Interest
Mar 28, 1994
From: COHEN, AHARON S.; BELENKY, ALEXEI; OTT, CHRISTOPHER M.
To: HYBRIDON, INC.
Reel/Frame 006918/0578 →
Assignment of Assignor's Interest
May 31, 1994
From: SZYF, MOSHE; HOFE, ERIC VON
To: MCGILL UNIVERSITY; HYBRIDON, INC.
Reel/Frame 007013/0273 →
Assignment of Assignor's Interest
Jul 18, 1994
From: SMYTH, ADRIENNE P.
To: HYBRIDON, INC.
Reel/Frame 007111/0226 →
Assignment of Assignor's Interest
Jul 25, 1994
From: PARI, GREGORY S.
To: HYBRIDON, INC.
Reel/Frame 007066/0236 →
Assignment of Assignor's Interest
Nov 9, 1994
From: GOODCHILD, JOHN; LEONARD, THOMAS E.
To: HYBRIDON, INC.
Reel/Frame 007374/0910 →
Assignment of Assignor's Interest
Nov 17, 1994
From: AGRAWAL, SUDHIR; ZHAO, QIUYAN; HABUS, IVAN
To: HYBRIDON, INC.
Reel/Frame 007237/0535 →
Corrective Assignment to Correct Names of Conveying Parties. Previously Recorded on Reel 7224 - Frames 573-574.
Feb 13, 1995
From: GHIA, ATUL V.; BANERJEE, PRADIP; CHUANG, PATRICK
To: SONY ELECTRONICS, INC.
Reel/Frame 007334/0092 →
Assignment of Assignor's Interest
Feb 13, 1995
From: BHONGLE, NANDKUMAR; TANG, JIN YAN
To: HYBRIDON, INC.
Reel/Frame 007336/0591 →
Assignment of Assignor's Interest
Mar 2, 1995
From: ROBINSON, GREGORY S.
To: HYBRIDON, INC.
Reel/Frame 007443/0486 →
Assignment of Assignor's Interest
Apr 12, 1995
From: KANDIMALLA EKAMBAR R.; AGRAWAL, SUDHIR
To: HYBRIDON, INC.
Reel/Frame 007491/0720 →
Assignment of Assignor's Interest
Apr 13, 1995
From: GOODCHILD, JOHN; NESBITT, STEVEN M.
To: HYBRIDON, INC.
Reel/Frame 007500/0898 →
Assignment of Assignor's Interest
Apr 27, 1995
From: SMITH, LOIS ELAINE HODGSON
To: CHILDREN'S MEDICAL CENTER CORPORATION
Reel/Frame 007455/0498 →
Assignment of Assignor's Interest
Apr 27, 1995
From: ROBINSON, GREGORY S.
To: HYBRIDON, INC.
Reel/Frame 007455/0492 →
Assignment of Assignor's Interest
Jun 26, 1995
From: ZHANG, ZHAODA; TANG, JIMMY X.; TANG, JIN-YAN
To: HYBRIDON, INC.
Reel/Frame 007984/0646 →
Assignment of Assignor's Interest
Aug 2, 1995
From: BHONGLE, NANDKUMAR
To: HYBRIDON, INC.
Reel/Frame 007578/0501 →
Assignment of Assignor's Interest
Aug 2, 1995
From: AGRAWAL, SUDHIR; TANG, JIN YIN
To: HYBRIDON, INC.
Reel/Frame 007578/0522 →
Assignment of Assignor's Interest
Jul 29, 1996
From: ZHANG, ZHAODA; TANG, JIMMY X.; TANG, JIN-YAN
To: HYBRIDON, INC.
Reel/Frame 008046/0995 →
Assignment of Assignor's Interest
Apr 25, 1997
From: TEMSAMANI, JAMAL; AGRAWAL, SUDHIR
To: HYBRIDON, INC.
Reel/Frame 008471/0856 →
Assignment of Assignor's Interest
Oct 27, 2000
From: HYBRIDON, INC.
To: BOSTON BIOSYSTEMS, INC.
Reel/Frame 011284/0457 →
Assignment of Assignor's Interest
Jan 30, 2001
From: HYBRIDON, INC.
To: BOSTON BIOSYSTEMS, INC.
Reel/Frame 011742/0986 →