Patent Assignment
Reel/Frame 057788/0719
Merger and Change of Name
Recorded: 2021-10-13
Pages: 10
Assignee
GRAIL, LLC
1525 O'BRIEN DRIVE, MENLO PARK, CALIFORNIA, 94025
Covered Properties
(180)
Enrichment of Mutated Cell Free Nucleic Acids for Cancer Detection
Differential Tagging of Rna for Preparation of a Cell-Free Dna/Rna Sequencing Library
Application:
62/357,281 →
Differential Tagging of Rna for Preparation of a Cell-Free Dna/Rna Sequencing Library
Application:
62/368,025 →
Differential Tagging of Rna for Preparation of a Cell-Free Dna/Rna Sequencing Library
Differential Tagging of Rna for Preparation of a Cell-Free Dna/Rna Sequencing Library
Methods of Preparing Dual-Indexed DNA Libraries for Bisulfite Conversion Sequencing
Application:
62/373,261 →
Methods of Preparing Dual-Indexed DNA Libraries for Bisulfite Conversion Sequencing
Application:
62/397,650 →
Methods of Preparing Dual-Indexed DNA Libraries for Bisulfite Conversion Sequencing
Method for Accurate Quantification of Genomic Copies in Cell-Free Dna
Application:
16/325,122 →
Publication:
US 2021/0277457
Variant Based Disease Diagnostics and Tracking
Application:
62/286,103 →
Variant Based Disease Diagnostics and Tracking
Application:
15/411,879 →
Publication:
US 2017/0213008
Methods and Systems for High Fidelity Sequencing
Application:
16/071,244 →
Publication:
US 2019/0338349
Methods of Preparing and Analyzing Cell-Free Nucleic Acid Sequencing Libraries
Application:
62/399,167 →
Methods of Preparing and Analyzing Cell-Free Nucleic Acid Sequencing Libraries
Application:
62/456,029 →
Methods of Preparing and Analyzing Cell-Free Nucleic Acid Sequencing Libraries
Methods of Preparing and Analyzing Cell-Free Nucleic Acid Sequencing Libraries
Methods of Preparing and Analyzing Cell-Free Nucleic Acid Sequencing Libraries
Methods for Base Coverage Normalization and Use Thereof in Detecting Copy Number Variation
Application:
62/438,348 →
Base Coverage Normalization and Use Thereof in Detecting Copy Number Variation
Methods of Identifying Somatic Mutation Signatures for Early Cancer Detection
Application:
62/418,639 →
Methods of Identifying Somatic Mutational Signatures for Early Cancer Detection
Application:
62/469,984 →
Methods of Identifying Somatic Mutation Signatures for Early Cancer Detection
Application:
62/569,519 →
Methods of Identifying Somatic Mutational Signatures for Early Cancer Detection
Application:
15/806,310 →
Publication:
US 2018/0203974
Methods for Single-Stranded Nucleic Acid Library Preparation
Application:
62/414,528 →
Methods for Single-Stranded Nucleic Acid Library Preparation
Detecting Cross Contamination in Sequencing Data
Application:
62/460,268 →
Methods for Detecting Cross Contamination in Sequencing Data
Application:
62/525,653 →
Detecting Cross-Contamination in Sequencing Data Using Regression Techniques
Methods for Tagging and Amplifying Rna Template Molecules for Preparing Sequencing Libraries
Application:
62/433,172 →
Methods for Tagging and Amplifying Rna Template Molecules for Preparing Sequencing Libraries
Application:
15/839,386 →
Publication:
US 2018/0163201
Methods for Tagging and Amplifying Rna Template Molecules for Preparing Sequencing Libraries
Application:
17/198,140 →
Publication:
US 2021/0198662
Methods for High Efficiency Library Preparation Using Double-Stranded Adapters
Application:
62/438,911 →
Methods for High Efficiency Library Preparation Using Double-Stranded Adapters
Library Preparation and Use Thereof for Sequencing Based Error Correction and/or Variant Identification
Application:
62/480,210 →
Library Preparation and Use Thereof for Sequencing Based Error Correction and/or Variant Identification
Higher Target Capture Efficiency Using Probe Extension
Application:
62/480,199 →
Higher Target Capture Efficiency Using Probe Extension
Detecting Cross Contamination in Sequencing Data
Application:
62/525,655 →
Detecting Cross Contamination in Sequencing Data
Application:
62/534,868 →
Detecting Cross-Contamination in Sequencing Data
Application:
62/633,008 →
Detecting Cross-Contamination in Sequencing Data
Enhanced Ligation in Sequencing Library Preparation
Application:
62/479,001 →
Enhanced Ligation in Sequencing Library Preparation
Alignment Free Filtering for Targeted Fusion Transcripts
Application:
62/518,510 →
Alignment Free Filtering for Identifying Fusions
Enrichment of Short Nucleic Acid Fragments in Sequencing Library Preparation
Application:
62/564,891 →
Enrichment of Short Nucleic Acid Fragments in Sequencing Library Preparation
Identifying False Positive Variants Using A Significance Model
Application:
62/553,593 →
Identifying False Positive Variants Using a Significance Model
Application:
16/119,961 →
Publication:
US 2019/0073445
Site-Specific Noise Model for Targeted Sequencing
Application:
62/569,367 →
Site-Specific Noise Model for Targeted Sequencing
Application:
16/153,593 →
Publication:
US 2019/0108311
Joint Model for Targeted Sequencing
Application:
62/591,637 →
Models for Targeted Sequencing
Application:
62/642,301 →
Models for Targeted Sequencing
Application:
62/679,347 →
Models for Targeted Sequencing
Methods for Preparing a Sequencing Library from Single-Stranded Dna
Application:
62/558,760 →
Methods for Preparing a Sequencing Library from Single-Stranded Dna
Application:
16/647,419 →
Publication:
US 2020/0263170
Microsatellite Instability Detection
Application:
62/612,048 →
Microsatellite Instability Detection
Application:
62/699,685 →
Microsatellite Instability Detection
Application:
16/235,901 →
Publication:
US 2019/0206513
Multi-Assay Prediction Model for Cancer Detection
Application:
62/657,635 →
Multi-Assay Prediction Model for Cancer Detection
Application:
62/679,738 →
Multi-Assay Prediction Model for Cancer Detection
Application:
16/384,784 →
Publication:
US 2019/0316209
Machine Learning Variant Source Assignment
Application:
62/694,375 →
Machine Learning Variant Source Assignment
Application:
16/460,588 →
Publication:
US 2020/0013484
Error Removal Using Improved Library Preparation Methods
Application:
62/609,951 →
Error Removal Using Improved Library Preparation Methods
Application:
16/231,307 →
Publication:
US 2019/0237161
Filtering Edge Variants
Application:
62/610,917 →
Methods and Systems for Screening for Conditions
Methods of Preparing a Sequencing Library Enriched for Duplex Dna Molecules
Application:
62/608,538 →
Methods of Preparing a Sequencing Library Enriched for Duplex Dna Molecules
Application:
16/228,466 →
Publication:
US 2019/0185930
Methods for Enriching for Duplex Reads in Sequencing and Error Correction
Application:
62/599,580 →
Methods for Enriching for Duplex Reads in Sequencing and Error Correction
Methylation Fragment Anomaly Detection
Application:
62/642,480 →
Anomalous Fragment Detection and Classification
Method and System for Selecting, Managing, and Analyzing Data of High Dimensionality
Application:
62/642,461 →
Method and System for Selecting, Managing, and Analyzing Data of High Dimensionality
Identifying Copy Number Aberrations
Application:
62/642,507 →
Identifying Copy Number Aberrations
Application:
16/352,214 →
Publication:
US 2019/0287646
Methylation Markers and Targeted Methylation Probe Panel
Application:
62/651,643 →
Methylation Markers and Targeted Methylation Probe Panel
Application:
62/738,271 →
Source of Origin Deconvolution Based on Methylation Fragments in Cell-Free Dna Samples
Application:
62/784,353 →
Source of Origin Deconvolution Based on Methylation Fragments in Cell-Free Dna Samples
Cancer Classification Based on Methylation Fragments in Cell-Free Dna Samples
Application:
62/784,355 →
Anomalous Fragment Detection and Classification
Application:
62/899,919 →
Anomalous Fragment Detection and Classification
Application:
16/723,411 →
Publication:
US 2020/0239964
Models for Targeted Sequencing of Rna
Application:
62/738,949 →
Models for Targeted Sequencing of Rna
Application:
16/584,936 →
Publication:
US 2020/0105375
Systems and Methods for Classifying Subjects Using Frequencies of Variants in Cell-Free Nucleic Acid
Application:
62/658,479 →
Systems and Methods for Determining Tumor Fraction in Cell-Free Nucleic Acid
Application:
17/047,676 →
Publication:
US 2021/0104297
Systems and Methods for Using Fragment Lengths as a Predictor of Cancer
Application:
62/784,332 →
Systems and Methods for Using Fragment Lengths as a Predictor of Cancer
Application:
62/827,682 →
Systems and Methods for Using Fragment Lengths as a Predictor of Cancer
Application:
16/723,369 →
Publication:
US 2020/0219587
Methods for Detecting Disease Using Analysis of Rna
Application:
62/781,512 →
Methods for Detecting Disease Using Analysis of Rna
Application:
62/843,109 →
Methods for Detecting Disease Using Analysis of Rna
Mixture Model for Targeted Sequencing
Application:
62/738,965 →
Mixture Model for Targeted Sequencing
Application:
16/579,805 →
Publication:
US 2020/0105374
Systems and Methods for Classifying Patients with Respect to Multiple Cancer Classes
Application:
62/777,693 →
Systems and Methods for Classifying Patients with Respect to Multiple Cancer Classes
Systems and Methods for Using Pathogen Nucleic Acid Load to Determine Whether a Subject Has a Cancer Condition
Application:
62/662,198 →
Systems and Methods for Using Pathogen Nucleic Acid Load to Determine Whether a Subject Has a Cancer Condition
Application:
17/050,372 →
Publication:
US 2021/0115520
Convolutional Neural Network Systems and Methods for Data Classification
Application:
62/679,746 →
Convolutional Neural Network Systems and Methods for Data Classification
Inferring Selection in White Blood Cell Matched Cell-Free DNA Variants and/or in RNA Variants
Application:
62/673,779 →
Inferring Selection in White Blood Cell Matched Cell-Free Dna Variants and/or in Rna Variants
Application:
16/417,336 →
Publication:
US 2019/0355438
Cancer Tissue Source of Origin Prediction with Multi-Tier Analysis of Small Variants in Cell-Free Dna Samples
Application:
62/782,087 →
Cancer Tissue Source of Origin Prediction with Multi-Tier Analysis of Small Variants in Cell-Free Dna Samples
Application:
16/719,938 →
Publication:
US 2020/0203016
Needle-Based Devices and Methods for in Vivo Diagnostics of Disease Conditions
Application:
62/767,813 →
Needle-Based Devices and Methods for in Vivo Diagnostics of Disease Conditions
Methylation Markers and Targeted Methylation Probe Panel
Application:
62/737,836 →
Methylation Markers and Targeted Methylation Probe Panel
Methylation Markers and Targeted Methylation Probe Panel
Methods for generating sequencing pileups and memory management
Application:
62/685,823 →
Methods For Managing Sequencing Pileups
Application:
62/719,483 →
Methods for Managing Sequencing Pileups
Methylation-Based False Positive Duplicate Marking Reduction
Application:
62/828,899 →
Methylation-Based False Positive Duplicate Marking Reduction
Methylation Markers and Targeted Methylation Probe Panel for Diagnosis of Cancer and Tissue of Origin
Application:
62/797,170 →
Detecting Cancer, Cancer Tissue of Origin, and/or a Cancer Cell Type
Application:
17/384,241 →
Publication:
US 2022/0119890
Detecting Cancer, Cancer Tissue of Origin, and/or a Cancer Cell Type
Application:
17/384,251 →
Publication:
US 2022/0090207
Systems and Methods for Determining Whether a Subject Has a Cancer Condition Using Transfer Learning
Application:
62/851,486 →
Systems and Methods for Determining Whether a Subject Has a Cancer Condition Using Transfer Learning
Systems and Methods for Estimating Cell Source Fractions Using Methylation Information
Application:
62/781,549 →
Systems and Methods for Estimating Cell Source Fractions Using Methylation Information
Application:
16/719,902 →
Publication:
US 2020/0385813
Systems and Methods for Enriching for Cancer-Derived Fragments Using Fragment Size
Application:
62/818,013 →
Systems and Methods for Enriching for Cancer-Derived Fragments Using Fragment Size
Application:
62/854,888 →
Systems and Methods for Enriching for Cancer-Derived Fragments Using Fragment Size
Generating Cancer Detection Panels According to a Performance Metric
Application:
63/013,512 →
Generating Cancer Detection Panels According to a Performance Metric
Application:
17/233,548 →
Publication:
US 2021/0324477
Methylation Markers and Targeted Methylation Probe Panel for Diagnosis of Cancer and Tissue of Origin
Application:
62/797,174 →
Methylation Markers and Targeted Methylation Probe Panel for Diagnosis of Cancer and Tissue of Origin
Application:
62/797,176 →
Methylation Markers and Targeted Methylation Probe Panel for Diagnosis of Hematological Disorders
Application:
62/801,556 →
Methylation Markers and Targeted Methylation Probe Panel for Diagnosis of Hematological Disorders
Application:
62/965,327 →
Detecting Cancer, Cancer Tissue of Origin, and/or a Cancer Cell Type
Application:
17/393,609 →
Publication:
US 2022/0064737
Methylation Markers and Targeted Methylation Probe Panel for Diagnosis of Cancer Tissue of Origin
Application:
62/801,561 →
Methylation Markers and Targeted Methylation Probe Panel for Diagnosis of Cancer Tissue of Origin
Application:
62/965,342 →
Detecting Cancer, Cancer Tissue of Origin, and/or a Cancer Cell Type
Application:
17/393,625 →
Publication:
US 2022/0098672
Systems and Methods for Determining Consensus Base Calls in Nucleic Acid Sequencing
Application:
62/894,206 →
Systems and Methods for Determining Consensus Base Calls in Nucleic Acid Sequencing
Application:
17/006,124 →
Publication:
US 2021/0065847
Systems and Methods for Cancer Condition Determination Using Autoencoders
Application:
62/985,258 →
Systems and Methods for Cancer Condition Determination Using Autoencoders
Model-Based Featurization and Classification
Application:
62/847,223 →
Model-Based Featurization and Classification
Application:
62/855,289 →
Model-Based Featurization and Classification
Application:
63/002,169 →
Systems and Methods for Evaluating Longitudinal Biological Feature Data
Application:
62/941,012 →
Systems and Methods for Diagnosing a Disease Condition Using on-Target and Off-Target Sequencing Data
Application:
62/904,455 →
Systems and Methods for Diagnosing a Disease Condition Using on-Target and Off-Target Sequencing Data
Application:
17/023,185 →
Publication:
US 2021/0102262
Systems and Methods for Determining Tumor Fraction
Application:
62/877,755 →
Systems and Methods for Determining Tumor Fraction
Application:
16/936,901 →
Publication:
US 2021/0065842
Systems and Methods for Tumor Fraction Estimation
Application:
62/834,904 →
Systems and Methods for Tumor Fraction Estimation from Small Variants
Application:
62/972,375 →
Systems and Methods for Tumor Fraction Estimation from Small Variants
Application:
16/850,634 →
Publication:
US 2020/0340064
Cancer Classification Using Patch Convolutional Neural Networks
Application:
62/948,129 →
Systems and Methods for Using Neural Networks to Determine a Cancer State
Application:
63/003,087 →
Cancer Classification with Genomic Region Modeling
Application:
63/144,380 →
Cancer Classification with Genomic Region Modeling
Application:
17/216,551 →
Publication:
US 2021/0313006
Systems and Methods for Data Augmentation for Disease Discrimination
Application:
63/001,729 →
Cancer Classification with Synthetic Training Samples
Application:
63/154,667 →
Cancer Classification with Synthetic Training Samples
Application:
17/216,555 →
Publication:
US 2021/0310075
Detecting Cross-Contamination in Sequencing Data
Application:
63/080,670 →
Endpoint Analysis in Early Cancer Detection
Application:
62/922,223 →
Endpoint Analysis in Early Cancer Detection
Application:
17/066,821 →
Publication:
US 2021/0134394
Sample Validation for Cancer Classification
Application:
63/071,951 →
Cancer Classification with Tissue of Origin Thresholding
Application:
62/914,341 →
Cancer Classification with Tissue of Origin Thresholding
Application:
63/024,033 →
Cancer Classification with Tissue of Origin Thresholding
Application:
63/041,699 →
Cancer Classification with Tissue of Origin Thresholding
Application:
17/066,863 →
Publication:
US 2021/0125686
Identifying Methylation Patterns That Discriminate or Indicate a Cancer Condition
Application:
62/983,443 →
Identifying Methylation Patterns That Discriminate or Indicate a Cancer Condition
Systems and Methods for Estimating Cell Source Fractions Using Methylation Information
Application:
62/950,071 →
Systems and Methods for Estimating Cell Source Fractions Using Methylation Information
Application:
17/127,813 →
Publication:
US 2021/0295948
Systems and Methods for Calling Variants Using Methylation Sequencing Data
Application:
62/983,404 →
Systems and Methods for Using a Convolutional Neural Network to Detect Contamination
Application:
63/085,369 →
Enrichment for Methylated Dna Fragments, and Related Methods, Compositions and Kits
Application:
63/041,690 →
Methods for Analysis of Cell-Free Rna
Application:
63/039,886 →
Detection and Classification of Human Papillomavirus Associated Cancers
Application:
63/041,875 →
Methods of Analyzing Nucleic Acid Fragments
Application:
62/373,332 →
Methods of Analyzing Nucleic Acid Fragments
Methods of Analyzing Nucleic Acid Fragments
Related Assignments
(25)
Other recorded transfers of the patents in this record — the chain of ownership.
Assignment of Assignor's Interest
Aug 16, 2016
From: VALOUEV, ANTON; JAMSHIDI, ARASH
To: GRAIL, INC.
Reel/Frame 039457/0129 →
Assignment of Assignor's Interest
Sep 22, 2016
From: VALOUEV, ANTON; JAMSHIDI, ARASH
To: GRAIL, INC.
Reel/Frame 039835/0154 →
Assignment of Assignor's Interest
Sep 28, 2016
From: LARSON, MATT; KIM, H. JOHN; EATTOCK, NICK; JAMSHIDI, ARASH
To: GRAIL, INC.
Reel/Frame 039876/0250 →
Assignment of Assignor's Interest
Oct 13, 2016
From: VALOUEV, ANTON; JAMSHIDI, ARASH
To: GRAIL, INC.
Reel/Frame 040007/0264 →
Assignment of Assignor's Interest
Nov 15, 2016
From: LARSON, MATT; KIM, H. JOHN; EATTOCK, NICK; JAMSHIDI, ARASH
To: GRAIL, INC.
Reel/Frame 040331/0308 →
Assignment of Assignor's Interest
Nov 22, 2016
From: JAMSHIDI, ARASH
To: GRAIL, INC.
Reel/Frame 040405/0860 →
Assignment of Assignor's Interest
Nov 22, 2016
From: VENN, OLIVER CLAUDE
To: GRAIL, INC.
Reel/Frame 040405/0679 →
Assignment of Assignor's Interest
Nov 22, 2016
From: LARSON, MATTHEW H.; KIM, HYUNSUNG JOHN; EATTOCK, NICK; YANG, XIAO
To: GRAIL, INC.
Reel/Frame 040405/0113 →
Assignment of Assignor's Interest
Dec 19, 2016
From: VENN, OLIVER CLAUDE
To: LIGHTHOUSE CANCER DIAGNOSTICS, LIMITED
Reel/Frame 040672/0741 →
Assignment of Assignor's Interest
Dec 19, 2016
From: LIGHTHOUSE CANCER DIAGNOSTICS, LIMITED
To: GRAIL, INC.
Reel/Frame 040672/0749 →
Assignment of Assignor's Interest
Dec 19, 2016
From: VENN, OLIVER CLAUDE
To: GRAIL, INC.
Reel/Frame 040672/0784 →
Assignment of Assignor's Interest
Jan 11, 2017
From: BARBACIORU, CATALIN
To: GRAIL, INC.
Reel/Frame 040946/0250 →
Assignment of Assignor's Interest
Feb 24, 2017
From: SAKARYA, ONUR; BARBACIORU, CATALIN
To: GRAIL, INC.
Reel/Frame 041373/0944 →
Assignment of Assignor's Interest
Mar 27, 2017
From: LARSON, MATTHEW H.; KIM, HYUNSUNG J.; EATTOCK, NICK; YANG, XIAO
To: GRAIL, INC.
Reel/Frame 041756/0176 →
Assignment of Assignor's Interest
Mar 27, 2017
From: VENN, OLIVER CLAUDE
To: GRAIL, INC.
Reel/Frame 041752/0093 →
Assignment of Assignor's Interest
Apr 4, 2017
From: VENN, OLVIER CLAUDE
To: GRAIL, INC.
Reel/Frame 041844/0903 →
Assignment of Assignor's Interest
Aug 7, 2017
From: SAKARYA, ONUR; BARBACIORU, CATALIN
To: GRAIL, INC.
Reel/Frame 043217/0888 →
Assignment of Assignor's Interest
Aug 17, 2017
From: LARSON, MATTHEW; KIM, HYUNSUNG JOHN; EATTOCK, NICHOLAS; JAMSHIDI, ARASH
To: GRAIL, INC.
Reel/Frame 043320/0987 →
Assignment of Assignor's Interest
Sep 12, 2017
From: VALOUEV, ANTON; JAMSHIDI, ARASH
To: GRAIL, INC.
Reel/Frame 043565/0755 →
Assignment of Assignor's Interest
Nov 3, 2017
From: VENN, OLIVER CLAUDE
To: GRAIL, INC.
Reel/Frame 044028/0948 →
Assignment of Assignor's Interest
Nov 20, 2017
From: LARSON, MATTHEW H.; KIM, HYUNSUNG JOHN; EATTOCK, NICK; YANG, XIAO
To: GRAIL, INC.
Reel/Frame 044176/0651 →
Assignment of Assignor's Interest
Nov 30, 2017
From: JAMSHIDI, ARASH; AMINI, HAMED
To: GRAIL, INC.
Reel/Frame 044262/0186 →
Assignment of Assignor's Interest
Dec 11, 2017
From: VENN, OLIVER CLAUDE
To: GRAIL, INC.
Reel/Frame 044349/0245 →
Assignment of Assignor's Interest
Feb 1, 2018
From: BARBACIORU, CATALIN
To: GRAIL, INC.
Reel/Frame 044804/0114 →
Assignment of Assignor's Interest
Mar 14, 2018
From: SAKARYA, ONUR; BARBACIORU, CATALIN
To: GRAIL, INC.
Reel/Frame 045207/0157 →