Patent Assignment
Reel/Frame 073442/0864
Security Interest
Recorded: 2026-01-12
Pages: 14
Assignor
SPRUCE BIOSCIENCES, INC.
Executed: 2026-01-07
Assignee
AVENUE CAPITAL MANAGEMENT II, L.P.
ATTN: TODD GREENBARG, 11 WEST 42ND STREET, 9TH FLOOR, NEW YORK, NEW YORK, 10036
Covered Properties
(40)
Methods and Compositions for Treating Polycystic Ovary Syndrome
Application:
63/532,319 →
Corticotropin Releasing Factor Receptor Antagonists
Application:
17/586,228 →
Publication:
US 2022/0143037
Methods and Compositions for Treating Polycystic Ovary Syndrome
Application:
18/785,556 →
Publication:
US 2025/0206733
Crystalline Composition of Tildacerfont and Methods of Use and Preparation Thereof
Application:
18/310,463 →
Publication:
US 2024/0043432
Corticotropin Releasing Factor Receptor Antagonists
Application:
18/078,649 →
Publication:
US 2023/0321112
Methods of Treating Congenital Adrenal Hyperplasia
Application:
63/047,822 →
Crystalline Composition of Tildacerfont and Methods of Use and Preparation Thereof
Application:
18/598,559 →
Publication:
US 2024/0293421
Corticotropin Releasing Factor Receptor Antagonists
Corticotropin Releasing Factor Receptor Antagonists
Application:
62/545,393 →
Methods and Compositions for Treating Polycystic Ovary Syndrome
Methods of Treating Polycystic Ovary Syndrome
Application:
63/064,863 →
Crystalline Composition of Tildacerfont and Methods of Use and Preparation Thereof
Application:
63/340,874 →
Methods of Treating Congenital Adrenal Hyperplasia
Application:
17/578,149 →
Publication:
US 2022/0133742
Methods for Treating Testicular and Ovarian Adrenal Rest Tumors
Corticotropin Releasing Factor Receptor Antagonists
Application:
62/804,646 →
Corticotropin Releasing Factor Receptor Antagonists
Corticotropin Releasing Factor Receptor Antagonists
Corticotropin Releasing Factor Receptor Antagonists
Application:
62/545,406 →
Methods for Treating Testicular and Ovarian Adrenal Rest Tumors
Methods for Treating Testicular and Ovarian Adrenal Rest Tumors
Methods for Treating Testicular and Ovarian Adrenal Rest Tumors
Methods for Treating Testicular and Ovarian Adrenal Rest Tumors
Application:
18/941,832 →
Publication:
US 2025/0064812
Methods of Treating Congenital Adrenal Hyperplasia
Application:
62/876,176 →
Amorphous Solid Dispersion of Tildacerfont Formulations
Application:
63/563,111 →
Crystalline Composition of Tildacerfont and Methods of Use and Preparation Thereof
Corticotropin Releasing Factor Receptor Antagonists
Application:
16/639,541 →
Publication:
US 2021/0361664
Crystalline Composition of Tildacerfont and Methods of Use and Preparation Thereof
Application:
63/281,462 →
Corticotropin Releasing Factor Receptor Antagonists
Corticotropin Releasing Factor Receptor Antagonists
Application:
16/788,121 →
Publication:
US 2020/0255436
Tildacerfont Cocrystal Formulations
Application:
63/468,764 →
Methods for Treating Testicular and Ovarian Adrenal Rest Tumors
Application:
17/667,285 →
Publication:
US 2022/0211711
Methods and Compositions for Treating Polycystic Ovary Syndrome
Methods of Treating Congenital Adrenal Hyperplasia
Application:
18/438,060 →
Publication:
US 2024/0261300
Corticotropin Releasing Factor Receptor Antagonists
Application:
16/639,540 →
Publication:
US 2021/0137935
Corticotropin Releasing Factor Receptor Antagonists
Corticotropin Releasing Factor Receptor Antagonists
Crystalline Composition of Tildacerfont and Methods of Use and Preparation Thereof
PCT:
PCT/US2022/050436 ↗
Methods and Compositions for Treating Polycystic Ovary Syndrome
PCT:
PCT/US2024/041496 ↗
Tildacerfont Cocrystal Formulations
PCT:
PCT/US2024/030822 ↗
Amorphous Solid Dispersion of Tildacerfont Formulations
PCT:
PCT/US2025/018489 ↗
Related Assignments
(24)
Other recorded transfers of the patents in this record — the chain of ownership.
Assignment of Assignor's Interest
Apr 9, 2018
From: HOWERTON, ALEXIS; GERBER, HAL
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 045482/0874 →
Assignment of Assignor's Interest
Apr 9, 2018
From: HOWERTON, ALEXIS; GERBER, HAL
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 045482/0971 →
Assignment of Assignor's Interest
Apr 10, 2019
From: HOWERTON, ALEXIS; GERBER, HAL; KARABORNI, SAMI; GHOSH, SANGITA
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 048852/0869 →
Assignment of Assignor's Interest
Jul 9, 2020
From: GHOSH, SANGITA; BARNES, CHRISTOPHER; HUANG, MICHAEL
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 053169/0658 →
Assignment of Assignor's Interest
Jul 15, 2020
From: GHOSH, SANGITA; BARNES, CHRISTOPHER; HUANG, MICHAEL
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 053216/0762 →
Assignment of Assignor's Interest
Aug 17, 2020
From: BARNES, CHRISTOPHER; KARPF, DAVID; NOOR, MUSTAFA
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 053515/0366 →
Assignment of Assignor's Interest
Nov 6, 2020
From: HOWERTON, ALEXIS; GERBER, HAL
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 054296/0458 →
Assignment of Assignor's Interest
Jul 13, 2021
From: HOWERTON, ALEXIS; GERBER, HAL; HUANG, MICHAEL
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 057351/0265 →
Assignment of Assignor's Interest
Jan 27, 2022
From: HOWERTON, ALEXIS; GERBER, HAL; HUANG, MICHAEL
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 058887/0792 →
Assignment of Assignor's Interest
Mar 8, 2022
From: GHOSH, SANGITA; BARNES, CHRISTOPHER; HUANG, MICHAEL
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 059348/0659 →
Assignment of Assignor's Interest
Apr 26, 2022
From: REDDY, DASHARATHA; RAJAGOPAL, ASHOKRAJ; WANG, LU; BARNES, CHRISTOPHER
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 059732/0247 →
Assignment of Assignor's Interest
Jun 3, 2022
From: REDDY, DASHARATHA; RAJAGOPAL, ASHOKRAJ; WANG, LU; BARNES, CHRISTOPHER
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 060269/0972 →
Assignment of Assignor's Interest
Dec 9, 2022
From: HOWERTON, ALEXIS; GERBER, HAL; HUANG, MICHAEL
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 062113/0933 →
Assignment of Assignor's Interest
Apr 26, 2023
From: HOWERTON, ALEXIS; GERBER, HAL; HUANG, MICHAEL
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 063457/0764 →
Assignment of Assignor's Interest
May 1, 2023
From: REDDY, DASHARATHA; RAJAGOPAL, ASHOKRAJ; WANG, LU; BARNES, CHRISTOPHER
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 063498/0675 →
Assignment of Assignor's Interest
Aug 21, 2023
From: BARNES, CHRISTOPHER; KARPF, DAVID; NOOR, MUSTAFA
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 064654/0285 →
Assignment of Assignor's Interest
Sep 13, 2023
From: REDDY, DASHARATHA; RAJAGOPAL, ASHOKRAJ; WANG, LU; BARNES, CHRISTOPHER
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 064895/0817 →
Corrective Assignment to Correct the Application Number Previously Recorded at Reel: 064895 Frame: 0817. Assignor(S) Hereby Confirms the Assignment.
Oct 10, 2023
From: REDDY, DASHARATHA; RAJAGOPAL, ASHOKRAJ; WANG, LU; BARNES, CHRISTOPHER
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 065198/0958 →
Assignment of Assignor's Interest
Dec 6, 2023
From: REDDY, DASHARATHA; RAJAGOPAL, ASHOKRAJ; WANG, LU; CHARLTON, WILL
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 065773/0492 →
Assignment of Assignor's Interest
Mar 7, 2024
From: REDDY, DASHARATHA; RAJAGOPAL, ASHOKRAJ; WANG, LU; BARNES, CHRISTOPHER
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 066688/0634 →
Assignment of Assignor's Interest
Oct 24, 2024
From: BARNES, CHRISTOPHER; KARPF, DAVID; NOOR, MUSTAFA
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 069012/0066 →
Assignment of Assignor's Interest
Nov 11, 2024
From: HOWERTON, ALEXIS; GERBER, HAL
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 069204/0395 →
Assignment of Assignor's Interest
Feb 27, 2025
From: REDDY, DASHARATHA G.; RAJAGOPAL, ASHOKRAJ; WANG, LU
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 070357/0177 →
Assignment of Assignor's Interest
Aug 13, 2025
From: HOWERTON, ALEXIS; GERBER, HAL
To: SPRUCE BIOSCIENCES, INC.
Reel/Frame 072013/0129 →