IP Library › Granted Patent US 12,350,517
Granted Patent B2
US 12,350,517 · App. 17/520,498 · Granted Jul 8, 2025

Image-guided radiation treatment with imaging data using imaging radiation at different energy levels

Inventors: Petr Jordan (Redwood City, CA); Andriy Myronenko (San Mateo, CA); Jay B. West (Mountain View, CA); Calvin R. Maurer (San Jose, CA); Prashant Chopra (Foster City, CA); Anuj K Purwar (Pleasanton, CA); Christopher A. Janko (Redwood City, CA)
Assignee: Accuray Incorporated
A61N5/1037A61B6/482A61N5/1049A61B6/025A61B6/4035A61B6/5223A61B6/583A61N2005/1061A61N2005/1062A61N5/1067A61N5/1083
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Quick Facts
Patent No.
US 12,350,517
App. No.
17/520,498
Filed
Nov 5, 2021
Granted
Jul 8, 2025
Kind
B2
Art Unit
2884
USPC
378/62
Abstract

A method of image-guided radiation treatment is described. The method includes processing a first and second sets of image data to generate an enhanced image, wherein the enhanced image comprises a combination of the first and second sets of image data, wherein part or all of the image data comprises a target of a patient. The method also includes registering the enhanced image with another image to obtain a registration result and tracking the target using the registration result to generate tracking information. The method also includes directing treatment delivery to the target based on the tracking information obtained from the enhanced image.

Claims (42)

1. A method of image-guided radiation, the method comprising:

processing a first set of volumetric image data of a target and a second set of volumetric image data of the target to generate an enhanced image, wherein the first set of volumetric image data and the second set of volumetric image data include an overlapping portion of the target and respective non-overlapping portions of the target, and wherein generating the enhanced image comprises processing the first set of volumetric image data in conjunction with the second set of volumetric image data to perform a weighted combination of the overlapping portion on a voxelwise basis;

registering the enhanced image with another image to obtain a registration result;

tracking the target using the registration result to generate tracking information; and

directing treatment delivery to the target based on the tracking information obtained from the enhanced image.

2. The method of claim 1 , wherein the another image comprises a pre-treatment image.

3. The method of claim 1 , wherein the first set of volumetric image data and the second set of volumetric image data comprises at least part of the target.

4. The method of claim 1 further comprising generating the first set of volumetric image data of part or all of the target using imaging radiation at a first energy level and the second set of volumetric image data of part or all of the target using imaging radiation at a second energy level.

5. The method of claim 1 , wherein the another image comprises a computed tomography (CT) image.

6. The method of claim 1 , wherein directing treatment delivery comprises:

generating a treatment delivery beam using a treatment delivery system comprising a radiation source; and

directing the treatment delivery beam to the target based on the tracking information.

7. The method of claim 6 , wherein directing treatment delivery comprises adjusting an angle at which the treatment delivery beam is directed to the target.

8. The method of claim 1 , wherein directing treatment delivery comprises moving a treatment couch to position the target.

9. The method of claim 1 , wherein directing treatment delivery comprises adjusting a collimator to direct a treatment delivery beam to the target based on the tracking information.

10. A system, comprising:

a radiation source;

a processor, operatively coupled with the radiation source, to:

process a first set of volumetric image data of a target and a second set of volumetric image data of the target to generate a combined image, wherein the first set of volumetric image data and the second set of volumetric image data include an overlapping portion of the target and respective non-overlapping portions of the target, and wherein generating the combined image comprises processing the first set of volumetric image data in conjunction with the second set of volumetric image data to perform a weighted combination of the overlapping portion on a voxelwise basis;

register the combined image with another image to obtain a registration result;

track the target using the registration result to generate tracking information; and

direct treatment delivery to the target based on the tracking information obtained from the combined image.

11. The system of claim 10 , wherein the combined image is an enhanced image.

12. The system of claim 10 , further comprising a diagnostic imaging system to acquire the another image.

13. The system of claim 10 , wherein to direct treatment delivery, the processor is to:

cause the radiation source to generate a treatment delivery beam; and

direct the treatment delivery beam to the target based on the tracking information.

14. The system of claim 10 , further comprising a treatment couch, wherein the processor is operatively coupled with the treatment couch to position the target based on the tracking information.

15. The system of claim 10 , further comprising a collimator, wherein the processor is operatively coupled with the collimator to adjust the collimator to direct a treatment delivery beam to the target based on the tracking information.

16. A non-transitory machine readable medium that, when executed by a processor, causes the processor to:

process a first set of volumetric image data of a target and a second set of volumetric image data of the target to generate an enhanced image, wherein the first set of volumetric image data and the second set of volumetric image data include an overlapping portion of the target and respective non-overlapping portions of the target, and wherein generating the enhanced image comprises processing the first set of volumetric image data in conjunction with the second set of volumetric image data to perform a weighted combination of the overlapping portion on a voxelwise basis;

register the enhanced image with another image to obtain a registration result;

track the target using the registration result to generate tracking information; and

direct treatment delivery to the target based on the tracking information obtained from the enhanced image.

17. The non-transitory machine readable medium of claim 16 , wherein the another image comprises a pre-treatment image.

18. The non-transitory machine readable medium of claim 16 , wherein the processor is further to track information obtained from the enhanced image which comprises a position of the target.

19. The non-transitory machine readable medium of claim 16 , wherein to direct treatment delivery, the processor is to:

generate a treatment delivery beam using a treatment delivery system comprising a radiation source; and

direct the treatment delivery beam to the target based on the tracking information.

20. The non-transitory machine readable medium of claim 19 , wherein to direct treatment delivery, the processor is further to adjust an angle at which the treatment delivery beam is directed to the target.

21. The non-transitory machine readable medium of claim 16 , wherein to direct treatment delivery, the processor is to move a treatment couch to position the target.

22. The non-transitory machine readable medium of claim 16 , wherein to direct treatment delivery, the processor is to adjust a collimator to direct a treatment delivery beam to the target based on the tracking information.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 13, 2025
From: ACCURAY INCORPORATED
To: ACCURAY LLC
Reel/Frame 072421/0584 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 5, 2025
From: JORDAN, PETR; CHOPRA, PRASHANT; MYRONENKO, ANDRIY; WEST, JAY B.; MAURER, CALVIN R., JR.; PURWAR, ANUJ K.; JANKO, CHRISTOPHER A.
To: ACCURAY, INC.
Reel/Frame 071331/0231 →
Continuity (6)
Continuation 17083051 · Oct 28, 2020
Continuation 16679686 · Nov 11, 2019
Continuation 15208049 · Jul 12, 2016
Continuation 13536737 · Jun 28, 2012
Provisional Application 61550309 · Oct 21, 2011
Related Publication 20220054860A1 · Feb 24, 2022
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