IP Library Granted Patent US 12661047
Granted Patent B2
US 12661047 · App. 17/880,109 · Granted Jun 23, 2026

Detrusor pressure estimation from single channel bladder pressure recordings

Inventors: Margot S. Damaser (Cleveland Heights, OH); Steve Majerus (Cleveland Heights, OH); Mohamed Abdelhady (Cleveland, OH)
Assignees: THE CLEVELAND CLINIC FOUNDATION; THE DEPARTMENT OF VETERANS AFFAIRS
A61B5/205A61B5/6852A61B5/7203A61B5/726
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Quick Facts
Patent No.
US 12661047
App. No.
17/880,109
Granted
Jun 23, 2026
Kind
B2
Abstract

To perform urological diagnostics of a patient, detrusor pressure can be estimated using bladder pressure recordings from a single sensor. A signal comprising the bladder pressure data recorded by the sensor can be received. The bladder pressure data can include at least a detrusor pressure data component and a corrupting data component. An estimate of the corrupting data component can be extracted from the bladder pressure data. The detrusor pressure of the patient can be estimated based on the estimate of the corrupting data component and/or the estimate of the detrusor pressure data. An output indicative of the detrusor pressure of the patient can be provided based on the estimate of the detrusor pressure data component.

Claims (16)

1 . A system configured for urological diagnostics of a patient, the system comprising:

a sensor configured to detect bladder vesical pressure data, wherein the bladder vesical pressure data comprises at least a detrusor pressure data component and a corrupting data component;

a controller, coupled to the sensor, comprising a processor configured to:

receive a signal comprising the bladder vesical pressure data from the sensor;

extract an estimate of the corrupting data component from the bladder vesical pressure data;

estimate the detrusor pressure data component of the patient based on a difference between the estimate of the corrupting data component and the bladder vesical pressure data; and

provide an output indicative of a detrusor pressure of the patient based on the estimate of the detrusor pressure data component.

2 . The system of claim 1 , wherein the estimate of the corrupting data component is extracted based on one or more mathematical transforms of the bladder vesical pressure data.

3 . The system of claim 1 , wherein the output is provided in real-time with the sensor detecting the bladder vesical pressure data.

4 . The system of claim 1 , wherein the sensor is within a catheter, wherein the catheter is configured to be inserted in the patient's urethra to the bladder such that the sensor is within the bladder.

5 . The system of claim 1 , wherein the corrupting data component is extracted by employing at least one time-invariant extraction technique and at least one time-variant extraction technique.

6 . The system of claim 5 , wherein the bladder vesical pressure data is wavelet transformed and the wavelet transformed bladder vesical pressure data comprises detail coefficients and approximation coefficients,

wherein the approximation coefficients relate to the detrusor pressure data component and the detail coefficients relate to the corrupting data component.

7 . The system of claim 6 , wherein the extraction comprises filtering the detail coefficients related to the corrupting data component.

8 . The system of claim 1 , wherein the processor is further configured to account for a variable relationship between the detrusor pressure data component and the corrupting data component as the bladder empties or fills.

9 . The system of claim 1 , wherein the corrupting data component comprises abdominal pressure data and/or artifact data.