IP Library Granted Patent US 12661078
Granted Patent B2
US 12661078 · App. 17/393,524 · Granted Jun 23, 2026

Method, device, and system for determining abnormality in myocardium region

Inventors: Muniraju M (Bengaluru, IN); Laxmikanta Shanbhag (Bengaluru, IN)
Assignee: Siemens Healthineers AG
A61B6/507A61B6/504A61B6/5247A61B8/06A61B8/0891A61B8/5261
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Quick Facts
Patent No.
US 12661078
App. No.
17/393,524
Granted
Jun 23, 2026
Kind
B2
Abstract

A method, device, and system for determining at least one blood vessel contributing to an abnormality in a myocardium region are provided. The method includes receiving from a medical imaging device a medical image associated with the myocardium region. The method further includes identifying from the medical image a region of abnormality in the myocardium region. Additionally, the method includes generating a simulation of a plurality of blood vessels associated with the myocardium region. The method includes determining from the simulation of the plurality of blood vessels at least one blood vessel contributing to the abnormality in the myocardium region. The at least one blood vessel is associated with the region of abnormality in the myocardium region.

Claims (83)

1 . A method of determining at least one blood vessel contributing to an abnormality in a myocardium region of a patient, the method comprising:

receiving from a medical imaging device a medical image associated with the myocardium region of the patient;

identifying from the medical image a region of abnormality in the myocardium region of the patient;

generating a simulation of a three-dimensional virtual model of a plurality of blood vessels associated with a myocardium region of one or more other patients, the three-dimensional virtual model being based on medical data associated with the myocardium region of the one or more other patients, the medical data being obtained by the medical imaging device from a medical database; and

determining, from the simulation of the three-dimensional virtual model of the plurality of blood vessels associated with the myocardium region of the one or more other patients, at least one blood vessel contributing to the abnormality in the myocardium region of the patient,

wherein the at least one blood vessel is associated with the region of abnormality in the myocardium region of the patient,

wherein generating the simulation of the three-dimensional virtual model of the plurality of blood vessels comprises:

determining the plurality of blood vessels associated with the myocardium region of the one or more other patients from the medical data associated with the myocardium region of the one or more other patients; and

generating the three-dimensional virtual model of the plurality of blood vessels associated with the myocardium region of the one or more other patients, and

wherein the medical data associated with the myocardium region of the one or more other patients is further associated with nomenclature and segmentation information associated with the myocardium region and the plurality of blood vessels.

2 . The method of claim 1 , wherein identifying the region of abnormality in the myocardium region of the patient comprises:

obtaining from the medical database the medical data associated with the myocardium region of the one or more other patients;

determining from the medical image a point of abnormality;

mapping the point of abnormality in the medical image with the medical data associated with the myocardium region of the one or more other patients; and

identifying the region of abnormality in the myocardium region of the patient based on the mapping.

3 . The method of claim 1 , wherein generating the simulation of the three-dimensional virtual model of the plurality of blood vessels further comprises:

generating a mask overlay on the plurality of blood vessels; and

segmenting the masked plurality of blood vessels for generation of the three- dimensional virtual model of the plurality of blood vessels.

4 . The method of claim 1 , further comprising:

determining a centerline associated with each blood vessel of the plurality of blood vessels;

identifying a distal end of the centerline associated with each blood vessel of the plurality of blood vessels;

generating one or more voxels originating from the distal end of the centerline of each vessel of the plurality of blood vessels; and

generating an updated three-dimensional virtual model of the plurality of blood vessels based on the generated one or more voxels.

5 . The method of claim 1 , wherein a proximal end of the simulation of the three-dimensional virtual model of the plurality of blood vessels connect to the myocardium region identified from the medical image.

6 . The method of claim 1 , wherein determining the at least one blood vessel contributing to the abnormality in the myocardium region of the patient comprises:

comparing the medical data associated with the myocardium region of the one or more other patients with the simulation of the three-dimensional virtual model of the plurality of blood vessels; and

determining from the comparison the at least one blood vessel connecting to the region of abnormality in the myocardium region of the patient.

7 . The method of claim 1 , wherein the medical image is a 3-dimensional medical image.

8 . The method of claim 1 , wherein the medical image is a computed tomography image, an X-ray fluoroscopic image, a magnetic resonance imaging based image, an ultrasound image, or any combination thereof.

9 . A medical imaging device for determining at least one blood vessel contributing to an abnormality in a myocardium region of a patient, the medical imaging device comprising:

one or more processing units;

a scanner unit configured to capture one or more medical images; and

a memory coupled to the one or more processing units, the memory comprising a module configured to:

receive from a medical imaging device a medical image associated with the myocardium region of the patient;

identify from the medical image a region of abnormality in the myocardium region of the patient;

generate a simulation of a three-dimensional virtual model of a plurality of blood vessels associated with a myocardium region of one or more other patients, the three-dimensional virtual model being based on medical data associated with the myocardium region of the one or more other patients, the medical data being obtained by the medical imaging device from a medical database; and

determine, from the simulation of the three-dimensional virtual model of the plurality of blood vessels, at least one blood vessel contributing to the abnormality in the myocardium region of the patient, wherein the at least one blood vessel is associated with the region of abnormality in the myocardium region of the patient,

wherein the generation of the simulation of the three-dimensional virtual model of the plurality of blood vessels comprises:

determination of the plurality of blood vessels associated with the myocardium region of the one or more other patients from the medical data associated with the myocardium region of the one or more other patients; and

generation of the three-dimensional virtual model of the plurality of blood vessels associated with the myocardium region of the one or more other patients, and

wherein the medical data associated with the myocardium region of the one or more other patients is further associated with nomenclature and segmentation information associated with the myocardium region and the plurality of blood vessels.

10 . A system for determining at least one blood vessel contributing to an abnormality in a myocardium region of a patient, the system comprising:

one or more servers; and

a medical imaging device coupled to the one or more servers,

wherein the one or more servers comprise one or more instructions that, when executed, cause the one or more servers to:

receive from a medical imaging device a medical image associated with the myocardium region of the patient;

identify from the medical image a region of abnormality in the myocardium region of the patient;

generate a simulation of a three-dimensional virtual model of a plurality of blood vessels associated with a myocardium region of one or more other patients, the three-dimensional virtual model being based on medical data associated with the myocardium region of the one or more other patients, the medical data being obtained by the medical imaging device from a medical database; and

determine, from the simulation of the three-dimensional virtual model of the plurality of blood vessels, at least one blood vessel contributing to the abnormality in the myocardium region of the patient,

wherein the at least one blood vessel is associated with the region of abnormality in the myocardium region of the patient,

wherein the generation of the simulation of the three-dimensional virtual model of the plurality of blood vessels comprises:

determination of the plurality of blood vessels associated with the myocardium region of the one or more other patients from the medical data associated with the myocardium region of the one or more other patients; and

generation of the three-dimensional virtual model of the plurality of blood vessels associated with the myocardium region of the one or more other patients, and

wherein the medical data associated with the myocardium region of the one or more other patients is further associated with nomenclature and segmentation information associated with the myocardium region and the plurality of blood vessels.

11 . A non-transitory computer-readable storage medium that stores machine readable instructions executable by a processing unit to determine at least one blood vessel contributing to an abnormality in a myocardium region of a patient, the computer readable instructions comprising:

receiving from a medical imaging device a medical image associated with the myocardium region of the patient;

identifying from the medical image a region of abnormality in the myocardium region of the patient;

generating a simulation of a three-dimensional virtual model of a plurality of blood vessels associated with a myocardium region of one or more other patients, the three-dimensional virtual model being based on medical data associated with the myocardium region of the one or more other patients, the medical data being obtained by the medical imaging device from a medical database; and

determining, from the simulation of the three-dimensional virtual model of the plurality of blood vessels, at least one blood vessel contributing to the abnormality in the myocardium region of the patient,

wherein the at least one blood vessel is associated with the region of abnormality in the myocardium region of the patient,

wherein generating the simulation of the three-dimensional virtual model of the plurality of blood vessels comprises:

determining the plurality of blood vessels associated with the myocardium region of the one or more other patients from the medical data associated with the myocardium region of the one or more other patients; and

generating the three-dimensional virtual model of the plurality of blood vessels associated with the myocardium region of the one or more other patients, and

wherein the medical data associated with the myocardium region of the one or more other patients is further associated with nomenclature and segmentation information associated with the myocardium region and the plurality of blood vessels.

12 . The non-transitory computer-readable storage medium of claim 11 , wherein identifying the region of abnormality in the myocardium region of the patient comprises:

obtaining from the medical database the medical data associated with the myocardium region of the one or more other patients;

determining from the medical image a point of abnormality;

mapping the point of abnormality in the medical image with the medical data associated with the myocardium region of the one or more other patients; and

identifying the region of abnormality in the myocardium region of the patient based on the mapping.

13 . The non-transitory computer-readable storage medium of claim 11 , wherein generating the simulation of the three-dimensional virtual model of the plurality of blood vessels further comprises:

generating a mask overlay on the plurality of blood vessels; and

segmenting the masked plurality of blood vessels for generation of the three-dimensional virtual model of the plurality of blood vessels.

14 . The non-transitory computer-readable storage medium of claim 11 , wherein the computer readable instructions further comprise:

determining a centerline associated with each blood vessel of the plurality of blood vessels;

identifying a distal end of the centerline associated with each blood vessel of the plurality of blood vessels;

generating one or more voxels originating from the distal end of the centerline of each vessel of the plurality of blood vessels; and

generating an updated three-dimensional virtual model of the plurality of blood vessels based on the generated one or more voxels.

15 . The non-transitory computer-readable storage medium of claim 11 , wherein a proximal end of the simulation of the three-dimensional virtual model of the plurality of blood vessels connect to the myocardium region identified from the medical image.

16 . The non-transitory computer-readable storage medium of claim 11 , wherein determining the at least one blood vessel contributing to the abnormality in the myocardium region of the patient comprises:

comparing the medical data associated with the myocardium region of the one or more other patients with the simulation of the three-dimensional virtual model of the plurality of blood vessels; and

determining from the comparison the at least one blood vessel connecting to the region of abnormality in the myocardium region of the patient.

17 . The non-transitory computer-readable storage medium of claim 11 , wherein the medical image is a 3-dimensional medical image.

18 . The non-transitory computer-readable storage medium of claim 11 , wherein the medical image is a computed tomography image, an X-ray fluoroscopic image, a magnetic resonance imaging based image, an ultrasound image, or any combination thereof.