Atraumatically formed tissue compositions, devices and methods of preparation and treatment
A process and system provides for atraumatic preparation of morselized Tissue Particles (TP)s, such as Full Thickness Skin Graft Particles (FTSGPs), cartilage particles and other organ tissue particles, in a liquid medium. The resultant tissue product may be a suspension of Tissue Particles in an aqueous solution and containing highly viable cells and may be rapidly prepared at bedside or in the operating room and conveniently delivered to a patient through a syringe or similar applicator. The morselized Tissues Particles may be used for surgical applications including wound healing, cosmetic surgery, and orthopedic cartilage repairs.
1 . A process for wound healing treatment using autologous micrograft tissue comprising;
excising a tissue biopsy;
placing said biopsy and a sterile fluid in an aseptic container;
morselizing said biopsy into morsels in said container by repeated/umatically slicing said biopsy between a pair of cutting blades supported in juxtaposition while maintaining viability of the morsels;
separating said morsels from said fluid;
transferring said morsels to a dispenser; and
dispensing said morsels over a surface of said wound.
2 . A process of claim 1 further including draining said fluid from said container.
3 . A process of claim 1 further including a dispensing device removably attached to said container.
4 . A process of claim 3 , wherein said dispensing device is a syringe.
5 . A process of claim 2 further including an isolation chamber in communication between said container and said dispensing device.
6 . A process of claim 5 , wherein said isolation chamber includes an inlet and outlet for receiving and recirculating said morsels back into said container for further processing.
7 . A process of claim 6 , wherein said isolation chamber includes a filter.
8 . A process of claim 7 , wherein said filter is cylindrical.
9 . A process of claim 8 further including a piston plunger for positioning within said cylindrical filter for facilitating transfer of said morsels into said dispensing device.
10 . A process of claim 9 further including a channel in fluid communication with said dispensing device and said container and wherein said channel includes an openable valve.