IP Library › Granted Patent US 12661372
Granted Patent B2
US 12661372 · App. 18/682,135 · Granted Jun 23, 2026

Pharmaceutical composition comprising poloxamer 188 for improving the filtering function of kidneys

Inventors: Elena Valentinovna Arshintseva (Republic of Mordovia, RU); Sergei Yurevich Pushkin (Noginsk-9, RU)
A61K31/765A61P13/12
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Quick Facts
Patent No.
US 12661372
App. No.
18/682,135
Granted
Jun 23, 2026
Kind
B2
Abstract

The invention relates to the field of medicine and veterinary medicine, in particular to a pharmaceutical composition for improving the filtering function of kidneys. A pharmaceutical composition for improving the filtering function of the kidneys of a subject, comprising poloxamer-188 as a pharmacologically active substance and at least one excipient. A pharmaceutical composition for improving the filtering function of kidneys is developed, the components of which ensure the achievement of the technical result consisting in a substantial reduction in side effects resulting from its use in comparison with the closest analogue.

Claims (4)

1 . A method for improving the filtering function of the kidneys of a subject, comprising administering a composition of poloxamer-188 as a pharmacologically active substance and at least one excipient; wherein the single daily dose of poloxamer-188 is from 8.6 to 90.0 mg/kg of body weight of the subject.

2 . The method of claim 1 , wherein the composition is in the form of a solution for oral administration.

3 . The method of claim 1 , wherein the subject is a mammal.

4 . The method of claim 3 , wherein the composition is administered to a mammal on a daily basis for 6 months.