Hydrophilic coatings for medical devices
Hydrophilic coatings including a polymer matrix having voids wherein microparticles having a lubricious liquid are located within the voids.
1 . A lubricious hydrophilic coating on a medical device, comprising:
a cured hydrophilic polymer forming a hydrophilic coating on the medical device, the cured hydrophilic polymer comprising an outer surface and a matrix having voids; and
microparticles comprising a polysaccharide and water, the microparticles located in the voids of the matrix of the cured hydrophilic polymer, the microparticles configured to release the water, wherein the water migrates to the outer surface of the hydrophilic coating and the water hydrates the hydrophilic coating, thereby rendering the hydrophilic coating lubricious.
2 . The lubricious hydrophilic coating on the medical device of claim 1 , wherein the microparticles comprise microcapsules.
3 . The lubricious hydrophilic coating on the medical device of claim 1 , wherein the microparticles comprise micelles.
4 . The lubricious hydrophilic coating on the medical device of claim 1 , wherein the water includes an additive.
5 . The lubricous hydrophilic coating on the medical device of claim 4 , wherein the additive comprises an osmolality increasing additive.
6 . The lubricious hydrophilic coating on the medical device of claim 1 , wherein the polysaccharide is a gelling agent.
7 . The lubricious hydrophilic coating on the medical device of claim 1 , wherein the polysaccharide is a hydrocolloid.
8 . The lubricious hydrophilic coating on the medical device of claim 1 , wherein the polysaccharide comprises gellan gum.
9 . The lubricious hydrophilic coating on the medical device of claim 8 , wherein the microparticles comprise microgels.
10 . The lubricious hydrophilic coating on the medical device of claim 1 , wherein the cured hydrophilic polymer comprises polyvinylpyrrolidone.
11 . The lubricious hydrophilic coating on the medical device of claim 1 , wherein the microparticles release the water upon a compression force being applied to an outer surface of the hydrophilic coating.
12 . The lubricious hydrophilic coating on the medical device of claim 1 , wherein the water migrates to an outer surface of the hydrophilic coating upon a compression force being applied to the outer surface of the hydrophilic coating.
13 . The lubricious hydrophilic coating on the medical device of claim 1 , wherein the medical device comprises a urinary catheter.
14 . The lubricious hydrophilic coating on the medical device of claim 13 , wherein the urinary catheter comprises a catheter shaft having a surface and the hydrophilic coating is located on the surface.
15 . A lubricious hydrophilic coating on a urinary catheter, comprising:
a cured hydrophilic polymer forming a hydrophilic coating on the urinary catheter, the cured hydrophilic polymer comprising an outer surface and a matrix having voids; and
microparticles comprising a polysaccharide and water, the microparticles located in the voids of the matrix of the cured hydrophilic polymer, the microparticles configured to release the water, wherein the water migrates to the outer surface of the hydrophilic coating and the water hydrates the hydrophilic coating, thereby rendering the hydrophilic coating lubricious.
16 . The lubricious hydrophilic coating on the urinary catheter of claim 15 , wherein the microparticles comprise microcapsules.
17 . The lubricious hydrophilic coating on the urinary catheter of claim 15 , wherein the microparticles comprise micelles.
18 . The lubricious hydrophilic coating on the urinary catheter of claim 15 , wherein the polysaccharide is a gelling agent.
19 . The lubricious hydrophilic coating on the urinary catheter of claim 15 , wherein the polysaccharide is a hydrocolloid.
20 . The lubricious hydrophilic coating on the urinary catheter of claim 15 , wherein the polysaccharide comprises gellan gum.