IP Library Granted Patent US 12661513
Granted Patent B2
US 12661513 · App. 18/388,553 · Granted Jun 23, 2026

Method for accessing the glossopharyngeal nerve

Inventors: Francis A. Papay (Westlake, OH); Abeer Kalandar (Cleveland, OH)
Assignee: THE CLEVELAND CLINIC FOUNDATION
A61N1/3611A61N1/36057
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Quick Facts
Patent No.
US 12661513
App. No.
18/388,553
Granted
Jun 23, 2026
Kind
B2
Abstract

A method of treating a subject includes an incision step that includes making an incision adjacent to an earlobe of the subject; a dissecting step that includes dissecting anatomical structure of the subject to provide access to a glossopharyngeal nerve of the subject; and a coupling step that includes operatively coupling a neurostimulator to the glossopharyngeal nerve. The dissecting step includes dissecting a stylohyoid muscle and a posterior belly of a digastric muscle of the subject.

Claims (46)

1 . A method of treating a subject, the method comprising:

an incision step that includes making an incision adjacent to an earlobe of the subject;

a dissecting step that includes dissecting one or more anatomical structures of the subject to provide access to a glossopharyngeal nerve of the subject, wherein the dissecting step includes dissecting a stylohyoid muscle and a posterior belly of a digastric muscle of the subject; and

a coupling step that includes operatively coupling a neurostimulator to the glossopharyngeal nerve.

2 . The method of claim 1 , wherein the incision has a first portion that extends inferiorly around a base of the earlobe, and a second portion that extends inferiorly from the first portion along a posterior border of a sternocleidomastoid muscle.

3 . The method of claim 1 , wherein the incision is made through subcutaneous tissue of the subject down to a fascia of the subject.

4 . The method of claim 1 , wherein after the incision step and before the dissecting step, the method includes a step of sweeping and displacing a parotid gland of the subject to provide access to the stylohyoid muscle and posterior belly.

5 . The method of claim 4 , wherein the parotid gland is swept anteriorly and superiorly.

6 . The method of claim 1 , wherein the dissecting step includes dissecting the stylohyoid muscle and the posterior belly, and then dissecting a styloid process of the subject.

7 . The method of claim 6 , wherein the dissecting step includes performing a blunt dissection of the styloid process.

8 . The method of claim 6 , wherein the dissecting step includes removing at least a portion of the styloid process from the subject.

9 . The method of claim 1 , wherein the method includes a step of determining a region of the glossopharyngeal nerve based on at least one landmark from a group consisting of:

an inferior border of an external auditory canal of the subject,

a confluence of a mastoid process and a sternocleidomastoid muscle of the subject, and

a vertex of a mandibular gonial angle of the subject,

wherein the neurostimulator is coupled within the region of the glossopharyngeal nerve.

10 . The method of claim 9 , wherein the region of the glossopharyngeal nerve is determined based on at least one predetermined range from a group consisting of:

a first predetermined range that is inferior to the inferior border of the external auditory canal,

a second predetermined range that is anterior to the confluence of the mastoid process and the sternocleidomastoid muscle, and

a third predetermined range that is deep to the vertex of the mandibular gonial angle.

11 . The method of claim 10 , wherein:

the first predetermined range is around 3.4 cm,

the second predetermined range is around 1.4 cm, and

the third predetermined range is around 2.2 cm.

12 . The method of claim 10 , wherein:

the first predetermined range is at least 3.1 cm and at most 3.9 cm,

the second predetermined range is at least 1.2 cm and at most 1.6 cm, and

the third predetermined range is at least 1.9 cm and at most 2.5 cm.

13 . The method of claim 1 , further comprising a reconnecting step that includes reconnecting dissected portions of the stylohyoid muscle and the posterior belly.

14 . The method of claim 13 , wherein:

after the incision step and before the dissecting step, the method includes a step of

sweeping a parotid gland of the subject from an initial configuration to a displaced configuration to provide access to a styloid process, stylohyoid muscle, and posterior belly, and

after the reconnecting step, the method includes a step of sweeping the parotid gland

from the displaced configuration back to the initial configuration.

15 . The method of claim 13 , wherein after the reconnecting step, the method includes a closing step of closing the incision.

16 . The method of claim 1 , wherein the neurostimulator includes at least one electrode that is operatively coupled in electrical communication with the glossopharyngeal nerve.

17 . The method of claim 16 , wherein the neurostimulator further includes a neurostimulator circuit for supplying electrical current to the at least one electrode, the neurostimulator circuit including a wireless communication device for enabling wireless communication with another device.

18 . A neurostimulator for treating a subject, wherein the neurostimulator is configured to be implanted within the subject and coupled to a glossopharyngeal nerve of the subject using the method of claim 1 .

19 . The neurostimulator of claim 18 , the neurostimulator comprising an electrode configured for attachment to a region of the glossopharyngeal nerve, wherein the region is defined by at least one range from a group consisting of:

a first range that is inferior to an inferior border of an external auditory canal of the subject,

a second range that is anterior to a confluence of a mastoid process and a sternocleidomastoid muscle of the subject, and

a third range that is deep to a vertex of a mandibular gonial angle of the subject.

20 . The neurostimulator of claim 19 , wherein:

the first range is around 3.4 cm,

the second range is around 1.4 cm, and

the third range is around 2.2 cm.