Pipette tip and pipette system for capillary blood collection
The capillary blood pipette tip system of the present invention includes a pipette tip for collecting capillary blood including a sampling unit having a capillary tube having a first diameter so as to sample a capillary blood; a sample storage unit having a first extension end formed from a distal end of the capillary tube of the sampling unit so as to have a larger area than the sampling unit; a sealing unit closely adhered to a distal opening of the sample storage unit and broken by a quantitative syringe introduced from the outside; a shielding wall surrounding the sealing unit to prevent the sample from splashing from the sample storage unit to the outside when the sealing unit is broken by the quantitative syringe; and a handle unit which is held by a user to sample using the sampling unit; an immunoassay cartridge having at least one pipette tip mounting well having a plunger that presses a sample of a sampling unit of the pipette tip from the bottom to the top when the pipette tip is coupled to the top; and a quantitative syringe for quantitatively sampling the capillary blood collected in the upper part thereof by approaching through the upper part of the pipette tip, when the capillary blood from the sampling unit is collected in the upper part by the pressurization of the plunger during the coupling of the pipette tip to the immunoassay cartridge.
1 . A pipette tip for collecting capillary blood, comprising:
a sampling unit having a capillary tube with a first diameter for sampling capillary blood;
a sample storage unit having a first extension end formed from an end of the capillary tube of the sampling unit configured to have a larger cross-sectional area than the sampling unit;
a sealing unit adhered to an upper opening of the sample storage unit and configured to be broken by a syringe inserted through the sealing unit;
a handle unit having a shielding wall attached to and surrounding a circumference of the sealing unit, the handle unit is configured to prevent a sample from splashing from the sample storage unit when the sealing unit is broken by the syringe, and the handle unit is configured to be held by a user for sampling a sample by using the sampling unit; and
a filter unit received within a front end of the sample storage unit configured to absorb and store the capillary blood at a first extension end of the sampling unit and configured to separate the capillary blood into red cells and plasma in response to being pressurized through a front end opening of the sampling unit, wherein the sample storage unit is configured to store the plasma,
wherein an upper part of the pipette tip is configured to collect plasma from bottom to top in response to pressurization of a plunger through the front end opening of the sampling unit.
2 . The pipette tip for collecting capillary blood according to claim 1 , wherein the sample storage unit includes:
a tubular body;
an air-discharge hole which is formed on an upper side of the tubular body and from which air is discharged when the sealing unit is broken; and
an insertion-fitting and coupling unit for insertion-fitting coupling with respect to a cartridge for immunoassay or a storage tube for accommodating the sampling unit and the sample storage unit along an outer circumferential part of an upper end of the tubular body.
3 . The pipette tip for collecting capillary blood according to claim 1 wherein
the filter unit includes a porous membrane for separating the red blood cells and the plasma by a pressure equal to or greater than a predetermined pressure, and an upper surface of the filter unit is configured to preclude a sample stored in the sample storage unit from passing through the upper surface under a force of gravity.
4 . The pipette tip for collecting capillary blood according to claim 1 , wherein the sample storage unit has a second diameter larger than the first diameter of the capillary tube and a length of 50% to 80% of the length of the capillary tube, and the sample storage unit is configured to enable movement of the syringe in the sample storage unit.
5 . The pipette tip for collecting capillary blood according to claim 1 , wherein
the sealing unit is made of aluminum foil and thermally fused to a bottom of the sample storage unit.
6 . The pipette tip for collecting capillary blood according to claim 2 , further comprising a storage tube, wherein the storage tube includes:
a tube main body having one end blocked, the tube main body sized and configured to receive the sampling unit and the sample storage unit;
an inner circumferential insertion-fitting and coupling unit formed in an inner circumferential part of the tube main body to facilitate insertion-fitting coupling of the tube main body with respect to a part of the handle unit of the pipette tip; and
a support flange extending from the tube main body and supporting a second extension end of the handle unit.
7 . A capillary blood pipette system, comprising:
a pipette tip for collecting capillary blood including a sampling unit having a capillary tube having a first diameter configured to sample a capillary blood; a sample storage unit having a first extension end formed from a distal end of the capillary tube of the sampling unit configured to have a larger cross-sectional area than the sampling unit; a sealing unit adhered to a distal opening of the sample storage unit and configured to be broken by a syringe inserted through the sealing unit; a shielding wall attached to and surrounding the sealing unit to prevent a sample from splashing from the sample storage unit to the outside when in response to the sealing unit being broken by the quantitative syringe; and a handle unit configured to be which is held by a user to sample using the sampling unit;
an immunoassay cartridge having at least one pipette tip mounting well having a plunger that presses a sample of the sampling unit of the pipette tip from a bottom closed end of the at least one pipette tip mounting well to a top open end of the at least one pipette tip mounting well in response to the pipette tip being coupled to the top;
a syringe configured to quantitatively sample capillary blood collected in an upper part thereof by approaching through the upper part of the pipette tip, in response to the capillary blood from the sampling unit being collected in the upper part by pressurization of the plunger during coupling of the pipette tip to the immunoassay cartridge; and
a filter unit received within a front end of the sample storage unit, the filter unit configured to absorb and store the capillary blood along the first extension end of the sampling unit, wherein the filter unit is configured to separate the capillary blood into red blood cells and plasma in response to pressure through a front end opening of the sampling unit, wherein the sample storage unit is configured to store the plasma.
8 . The capillary blood pipette system according to claim 7 , wherein the sample storage unit includes:
a tubular body;
an air-discharge hole which is formed on an upper side of the tubular body and from which air is discharged when the sealing unit is broken; and
an insertion-fitting and coupling unit for insertion-fitting coupling with respect to the immunoassay cartridge for immunoassay or a storage tube for accommodating the sampling unit and the sample storage unit along an outer circumferential part of an upper end of the tubular body.
9 . The capillary blood pipette system according to claim 7 , wherein
the filter unit includes a porous membrane for separating the red blood cells and the plasma by a pressure equal to or greater than a predetermined pressure, and an upper surface of the filter unit is configured to preclude a sample stored in the sample storage unit from passing through the upper surface under a force of gravity.
10 . The capillary blood pipette system according to claim 7 , wherein the sample storage unit has a second diameter larger than the first diameter of the capillary tube and a length of 50% to 0% of the length of the capillary tube, and the sample storage unit is configured to enable movement of the syringe in the storage unit.
11 . The capillary blood pipette system according to claim 7 , wherein
the sealing unit is made of aluminum foil and thermally fused to a bottom of the sample storage unit.
12 . The capillary blood pipette system according to claim 8 , further comprising a storage tube, wherein the storage tube includes:
a tube main body having one end blocked, the tube main body sized and configured to receive the sampling unit and the sample storage unit;
an inner circumferential coupling unit formed in an inner circumferential part of the tube main body to facilitate insertion-fitting coupling of the tube main body with respect to a lower part of the handle unit of the pipette tip; and
a support flange extending from the tube main body and supporting a second extension end of the handle unit.
13 . The capillary blood pipette system according to claim 12 , wherein the storage tube includes a label unit provided on an outer wall of the tube main body of the storage tube, the label unit displaying patient information in a form of a barcode.
14 . The capillary blood pipette system according to claim 7 , wherein the plunger protrudes from a bottom of the at least one pipette tip mounting well in a form of a bar or a rod.
15 . The capillary blood pipette system according to claim 7 , wherein the plunger includes a bar or a rod and a support plate formed at a lower part of the bar or the rod, the plunger is detachably installed at a bottom of the at least one pipette tip mounting well.