IP Library › Granted Patent US 12662676
Granted Patent B2
US 12662676 · App. 17/607,102 · Granted Jun 23, 2026

Aptamer nucleic acid molecule, and complex and application thereof

Inventors: Yi Yang (Shanghai, CN); Linyong Zhu (Shanghai, CN); Xianjun Chen (Shanghai, CN); Dasheng Zhang (Shanghai, CN); Ni Su (Shanghai, CN); Qiuning Lin (Shanghai, CN)
Assignee: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY
C12N15/115C07C255/53C07C255/58C07D213/74C07D213/85C07D239/42C07D241/20C07D241/24C07D263/56C07D277/64C07D333/60C07D495/04C09K11/06C12N15/1003C12Q1/6876C09K2211/1007C09K2211/1018C12N2310/16C12N2310/351C12N2320/10
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Quick Facts
Patent No.
US 12662676
App. No.
17/607,102
Granted
Jun 23, 2026
Kind
B2
Abstract

The present application relates to an aptamer nucleic acid molecule, a complex containing the aptamer nucleic acid molecules, a method of detecting intracellular or extracellular RNA, DNA or other target molecules, and a kit containing the aptamer. The aptamer of the present application is capable of specifically binding a kind of fluorophore micromolecules, and can significantly enhance fluorescence intensity under excitation light of appropriate wavelength.

Claims (1)

1 . A nucleic acid aptamer comprising a sequence of any of SEQ ID NOs: 1-3, 6-19, 21-23.