Synergistic pulse generation apparatus, device and method

1 . A synergistic pulse generation apparatus for generating a pulse signal under the control of a host computer, comprising:

a driving circuit, which is electrically connected to the host computer, and is configured to receive a first control signal sent by the host computer and convert the first control signal into a first driving signal, and receive a second control signal sent by the host computer and convert the second control signal into a second driving signal; and

a pulse generation circuit, which comprises a first power supply, a first pulse generation module, which is electrically connected to the first power supply, a second power supply, and a second pulse generation module, which is electrically connected to the second power supply,

wherein the first pulse generation module is configured to store electric energy supplied by the first power supply, and discharge electricity under the control of the first driving signal to form a first pulse signal applied to a load; and

the second pulse generation module is configured to store electric energy supplied by the second power supply, and discharge electricity under the control of the second driving signal to form a second pulse signal applied to the load,

wherein the voltage of the second power supply is greater than the voltage of the first power supply, and the width of the second pulse signal is less than the width of the first pulse signal,

wherein the driving circuit comprises an electro-optical conversion module, a signal processing module and an optical fiber, which is electrically connected to the electro-optical conversion module and the signal processing module, respectively, wherein

the electro-optical conversion module is electrically connected to the host computer, and the signal processing module is electrically connected to the pulse generation circuit;

the electro-optical conversion module is configured to receive the first and second control signals sent by the host computer, convert the first and second control signals into first and second optical driving signals and send same to the signal processing module by means of the optical fiber; and

the signal processing module is configured to receive the first and second optical driving signals and convert the first and second optical driving signals into first and second electrical driving signals, process the first and second electrical driving signals to obtain the first and second driving signals, and transmit the first and second driving signals to the pulse generation circuit,

wherein the electro-optical conversion module comprises:

a buffer unit, which is electrically connected to the host computer, and is configured to receive the first and second control signals and buffer the first and second control signals;

a first signal amplification unit, which is electrically connected to the buffer unit, and is configured to perform amplification processing on the buffered first and second control signals; and

a first conversion unit, which is electrically connected to the first signal amplification unit and the optical fiber, respectively, and is configured to perform electro-optical conversion on the first and second control signals that have been subjected to amplification processing, so as to obtain the first and second optical driving signals, and send same to the signal processing module by means of the optical fiber, and

wherein the signal processing module comprises:

a second conversion unit, which is connected to the optical fiber and is configured to receive the first and second optical driving signals and convert the first and second optical driving signals into the first and second electrical driving signals;

a first filter unit, which is electrically connected to the second conversion unit and is configured to perform first filtering processing on the first and second electrical driving signals;

a second signal amplification unit which is electrically connected to the first filter unit, and is configured to perform amplification processing on the filtered first and second electrical driving signals to obtain third and fourth driving signals; and

a second filter unit, which is electrically connected to the second signal amplification unit and the pulse generation circuit, respectively, and is configured to perform second filtering processing on the third and fourth driving signals and send the third driving signal subjected to second filtering processing as the first driving signal and the fourth driving signal subjected to second filtering processing as the second driving signal to the pulse generation circuit,

wherein the driving circuit is configured to perform operations of buffering, amplifying and converting the first and second control signals into the first and second optical driving signals by the electro-optical conversion module and to perform operations of converting the first and second optical driving signals into the first and second electrical driving signals, and amplifying and filtering the first and second electrical driving signals to obtain the first and second driving signals by the signal processing module, so as to reduce influence of electromagnetic interference from the pulse generation circuit on the first and second driving signals.

2 . The synergistic pulse generation apparatus according to claim 1 , wherein the pulse generation circuit further comprises:

a first discharge module, which is electrically connected to the first pulse generation module and a ground, respectively, and is configured to connect the first pulse generation module to the ground under the control of a first discharge signal to release residual electricity in the first pulse generation module; and

a second discharge module, which is electrically connected to the second pulse generation module and the ground, respectively, and is configured to connect the second pulse generation module to the ground under the control of a second discharge signal to release residual electricity in the second pulse generation module.

3 . The synergistic pulse generation apparatus according to claim 1 , wherein the pulse generation circuit further comprises:

an output module, which comprises a trigger unit and at least a pair of electrodes, which are electrically connected to the trigger unit, wherein the trigger unit is electrically connected to the first pulse generation module and the second pulse generation module, respectively, the electrodes are in contact with the load, and when triggered by a trigger instruction, the trigger unit is configured to be switched on so that the first pulse signal and/or the second pulse signal are/is transmitted to the electrodes.

4 . The synergistic pulse generation apparatus according to claim 1 , wherein the pulse generation circuit further comprises:

a resistor, which is electrically connected to the first pulse generation module, the second pulse generation module and the ground, respectively, wherein the first pulse signal and/or the second pulse signal are/is also applied to the resistor; and

a monitoring module, which comprises a first monitoring unit and a second monitoring unit, wherein the first monitoring unit is configured to monitor currents outputted by the first pulse signal and the second pulse signal; and the second monitoring unit is configured to monitor voltages applied to the resistor by the first pulse signal and the second pulse signal.

5 . The synergistic pulse generation apparatus according to claim 1 , further comprising a circuit board, wherein

the circuit board comprises a first part and a second part, which is located at a side of the first part, the driving circuit is arranged at the first part, and the pulse generation circuit is arranged at the second part; or

the circuit board comprises a first circuit board and a second circuit board, the driving circuit is arranged at the first circuit board, and the pulse generation circuit is arranged at the second circuit board.

6 . The synergistic pulse generation apparatus according to claim 5 , further comprising: a shielding structure, which is arranged on the circuit board, wherein the driving circuit is located inside the shielding structure.

7 . The synergistic pulse generation apparatus according to claim 1 , wherein the first pulse signal is a microsecond pulse signal or a millisecond pulse signal, and the second pulse signal is a nanosecond pulse signal.

8 . The synergistic pulse generation apparatus according to claim 1 ,

wherein the buffer unit is a multi-channel buffer which comprises k signal buffer channels, each of the signal buffer channels being used for inputting of one of the first and second control signals and storing the one of the first and second control signals, and k being an integer greater than 1;

the first signal amplification unit comprises k first amplification sub-units, each of the first amplification sub-units being electrically connected to one signal buffer channel, and the first amplification sub-unit being used for performing amplification processing on the one of the first and second control signals stored in the corresponding signal buffer channel; and

the first conversion unit is an optical signal transmitter which comprises k electro-optical conversion channels, each of the electro-optical conversion channels being electrically connected to one first amplification sub-unit, and the electro-optical conversion channel being used for converting, into the first or second optical driving signal, the one of the first and second control signals subjected to amplification processing of the corresponding first amplification sub-unit, and transmitting the first or second optical driving signal to the signal processing module by means of the optical fiber.

9 . The synergistic pulse generation apparatus according to claim 1 , wherein

the second conversion unit is an optical signal receiver which comprises k photoelectric conversion channels, each of the photoelectric conversion channels being used for receiving one of the first and second optical driving signals and converting the one of the first and second optical driving signals into the first or second electrical driving signal, and k being an integer greater than 1;

the first filter unit comprises k first filter sub-units, each of the first filter sub-units being electrically connected to one photoelectric conversion channel, and the first filter sub-unit being used for performing first filtering processing on the first or second electrical driving signal obtained by means of conversion by the corresponding photoelectric conversion channel;

the second signal amplification unit comprises k second amplification sub-units, each of the second amplification sub-units being electrically connected to one first filter sub-unit, and the second amplification sub-unit being used for performing amplification processing on the first or second electrical driving signal subjected to first filtering processing of the corresponding first filter sub-unit, so as to obtain the third or fourth driving signal; and

the second filter unit comprises k second filter sub-units, each of the second filter sub-units being electrically connected to one second amplification sub-unit, and the second filter sub-unit being used for performing second filtering processing on the third or fourth driving signal obtained by means of amplification processing by the corresponding second amplification sub-unit, and sending the third driving signal subjected to second filtering as the first driving signal or the fourth driving signal subjected to second filtering as the second driving signal to the pulse generation circuit.

10 . The synergistic pulse generation apparatus according to claim 1 , wherein

the first pulse generation module comprises n stages of first pulse generation units configured to receive electric energy supplied by the first power supply with a first voltage and store same, and release stored electric energy when receiving a first control signal, so that x first pulse generation units receiving the first control signal discharge electricity to form a first pulse signal applied to a load, wherein n is an integer greater than or equal to 1, and x is an integer greater than or equal to 1 and less than or equal to n;

the second pulse generation module comprises m stages of second pulse generation units configured to receive electric energy supplied by the second power supply with a second voltage and store same, and release stored electric energy when receiving a second control signal, so that y second pulse generation units receiving the second control signal discharge electricity to form a second pulse signal applied to the load, wherein m is an integer greater than or equal to 1, and y is an integer greater than or equal to 1 and less than or equal to m; and

the second voltage is greater than the first voltage.

11 . The synergistic pulse generation apparatus according to claim 10 , wherein

the first pulse generation units each comprise a first storage unit, a first switch unit and a first cutoff unit,

wherein the first switch units are configured to receive the first control signal and switch on under the control of the first control signal, so that the respective first storage units at the same stages as those of the first switch units receiving the first control signal are connected in series and discharge electricity so as to form the first pulse signal, and

each of the first cutoff units is configured to only allow a charging current to flow from the first power supply to the respective first pulse generation unit, or flow from the current stage of the first pulse generation unit to the next stage of a first pulse generation unit, and only allow a discharging current to flow from the current stage of the first pulse generation unit to the next stage of the first pulse generation unit; and

the second pulse generation units each comprise a second storage unit, a second switch unit and a second cutoff unit,

wherein the second switch units are configured to receive the second control signal and switch on under the control of the second control signal, so that the respective second storage units at the same stages as those of the second switch units receiving the second control signal are connected in series and discharge electricity so as to form the second pulse, and

the second cutoff unit is configured to only allow a charging current to flow from the second power supply to the second pulse generation unit, or flow from the current stage of the second pulse generation unit to the next stage of the second pulse generation unit, and only allow a discharging current to flow from the current stage of the second pulse generation unit to the next stage of the second pulse generation unit.

12 . The synergistic pulse generation apparatus according to claim 11 , wherein

the first cutoff unit comprises a first cutoff device and a second cutoff device, a first-stage first cutoff device is electrically connected to a first end of the first power supply and a first end of a first-stage first storage unit, respectively, an ith-stage first cutoff device is electrically connected to a first end of an (i−1)th-stage first storage unit, a first end of an ith-stage first storage unit and an (i−1)th-stage first cutoff device, respectively, each stage of a second cutoff device is electrically connected to a second end of the current stage of a first storage unit, a second end of the current stage of a first switch unit and the next stage of a second cutoff device, respectively, and i is an integer greater than or equal to 2; and

the second cutoff units comprise a third cutoff device and a fourth cutoff device, a first-stage third cutoff device is electrically connected to a first end of the second power supply and a first end of a first-stage second storage unit, respectively, a jth-stage third cutoff device is electrically connected to a first end of a (j−1)th-stage second storage unit, a first end of a jth-stage second storage unit and a (j−1)th-stage third cutoff device, respectively, each stage of a fourth cutoff device is electrically connected to a second end of the current stage of a second storage unit, a second end of the current stage of a second switch unit and the next stage of a fourth cutoff device, respectively, and j is an integer greater than or equal to 2.

13 . The synergistic pulse generation apparatus according to claim 12 , wherein

the first storage unit comprises a first capacitor, and the second storage unit comprises a second capacitor;

the first switch unit comprises a first solid-state switch device, and the second switch unit comprises a second solid-state switch; and

the first cutoff device comprises a first diode, the second cutoff device comprises a second diode, the third cutoff device comprises a third diode, and the fourth cutoff device comprises a fourth diode.

14 . The synergistic pulse generation apparatus according to claim 11 , wherein

two ends of each stage of the first storage unit are electrically connected to two ends of the first power supply, respectively, a control end of each stage of the first switch unit is configured to receive the first control signal, and the first end and the second end of each stage of the first switch unit are electrically connected to the first end of the current stage of the first storage unit and the second end of the next stage of the first storage unit, respectively; and

two ends of each stage of the second storage unit are electrically connected to two ends of the second power supply, respectively, a control end of each stage of the second switch unit is configured to receive the second control signal, and the first end and the second end of each stage of the second switch unit are electrically connected to the first end of the current stage of the second storage unit and the second end of the next stage of the second storage unit, respectively.

15 . A synergistic pulse generation device, comprising:

a host computer configured to generate a first control signal and a second control signal according to an inputted instruction; and

a synergistic pulse generation apparatus according to claim 1 .

16 . The synergistic pulse generation device according to claim 15 , wherein the synergistic pulse generation device is an electroablation device; and a first pulse signal generated by the synergistic pulse generation apparatus is a microsecond pulse signal or a millisecond pulse signal, and a second pulse signal generated by the synergistic pulse generation apparatus is a nanosecond pulse signal.

17 . A synergistic pulse generation method used for the synergistic pulse generation apparatus according to claim 1 , the method comprising:

a first pulse generation module storing electric energy supplied by a first power supply, and a second pulse generation module storing electric energy supplied by a second power supply;

a driving circuit receiving a first control signal sent by a host computer and converting the first control signal into a first driving signal, and the driving circuit receiving a second control signal sent by the host computer and converting the second control signal into a second driving signal; and

a first pulse generation module receiving the first driving signal and discharging electricity under the control of the first driving signal to form a first pulse signal applied to a load, and a second pulse generation module receiving the second driving signal and discharging electricity under the control of the second driving signal to form a second pulse signal applied to the load,

wherein the voltage of the second power supply is greater than the voltage of the first power supply, and the width of the second pulse signal is less than the width of the first pulse signal,

wherein the driving circuit receiving a first control signal sent by a host computer and converting the first control signal into a first driving signal, comprises operations of:

S 1 : a buffer unit receiving and buffering the first control signal;

S 2 : a first signal amplification unit performing amplification processing on the buffered first control signal;

S 3 : a first conversion unit performing electro-optical conversion on the first control signal that has been subjected to amplification processing, so as to obtain a first optical driving signal, and send same to a second conversion unit by means of an optical fiber;

S 4 : the second conversion unit receiving the first optical driving signal and converting the first optical driving signal into a first electrical driving signal;

S 5 : a first filter unit performing first filtering processing on the first electrical driving signal;

S 6 : a second signal amplification unit performing amplification processing on the first electrical driving signal to obtain a third driving signal; and

S 7 : a second filter unit performing second filtering processing on the third driving signal and send the third driving signal subjected to second filtering processing as the first driving signal to the pulse generation circuit, and

wherein the driving circuit receiving a second control signal sent by the host computer and converting the second control signal into a second driving signal, comprises operations of:

S 1 ′: the buffer unit receiving and buffering the second control signal;

S 2 ′: the first signal amplification unit performing amplification processing on the buffered second control signal;

S 3 ′: the first conversion unit performing electro-optical conversion on the second control signal that has been subjected to amplification processing, so as to obtain a second optical driving signal, and send same to the second conversion unit by means of the optical fiber;

S 4 ′: the second conversion unit receiving the second optical driving signal and converting the second optical driving signal into a second electrical driving signal;

S 5 ′: the first filter unit performing first filtering processing on the second electrical driving signal;

S 6 ′: the second signal amplification unit performing amplification processing on the second electrical driving signal to obtain a fourth driving signal; and

S 7 ′: the second filter unit performing second filtering processing on the fourth driving signal and send the fourth driving signal subjected to second filtering processing as the second driving signal to the pulse generation circuit,

wherein in the method, the operations of S 1 -S 7 and S 1 ′-S 7 ′ allow to reduce influence of electromagnetic interference from the first pulse generation module and the second pulse generation module on the first driving signal and the second driving signal.