IP Library Granted Patent US 12667293
Granted Patent B2
US 12667293 · App. 18/264,182 · Granted Jun 30, 2026

Apparatus used to detect or stimulate activity of nerve tissue

Inventor: Yuji Matsumaru (Tsukuba, JP)
Assignees: Epsilon Medical Inc.; UNIVERSITY OF TSUKUBA
A61B5/293A61B5/6868A61B5/6876A61B5/6882A61N1/0539A61B2562/043
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Quick Facts
Patent No.
US 12667293
App. No.
18/264,182
Granted
Jun 30, 2026
Kind
B2
Abstract

This apparatus ( 1 ) comprises at least one intravascular device ( 10 ), ( 20 ) that is disposed in a blood vessel of an organism and that is equipped with at least one electrode ( 11 ), ( 12 ), ( 21 ), ( 22 ) for detecting or stimulating the activity of nerve tissue positioned outside the blood vessel nearby, the electrodes ( 11 ), ( 12 ), ( 21 ), ( 22 ) being provided on a wire member.

Claims (28)

1 . A method comprising:

disposing, in a cerebral blood vessel of an organism, an intravascular device including at least one electrode provided on a wire member; and

detecting activity of nerve tissue or stimulating of the nerve tissue with the electrode, the nerve tissue being positioned outside the blood vessel near the electrode,

wherein the wire member is formed from a single metal wire and an insulator covering the single metal wire, and

the electrode is provided in a ring shape around an entire circumference of the wire member, not covered by the insulator.

2 . The method according to claim 1 , wherein

the intravascular device is a single intravascular device or comprises a plurality of intravascular devices, and at least one of the intravascular devices has a plurality of the electrodes, and

the plurality of electrodes are provided on the same wire member and are spaced apart from each other by less than 1 cm.

3 . The method according to claim 1 , wherein the intravascular device comprises a plurality of intravascular devices, and the method further comprises:

using the plurality of intravascular devices, and

using electrodes included in the respective intravascular devices in such a manner that the electrodes are disposed in the blood vessel and are spaced apart from each other by 1 cm or more.

4 . The method according to claim 1 , wherein the wire member is expandable and contractable circumferentially, and includes a spiral portion, and the method further comprises:

retaining the spiral portion against a wall of the blood vessel in an expanded state.

5 . The method according to claim 1 , further comprising:

allowing the intravascular device to remain in the blood vessel for one day or longer.

6 . The method according to claim 1 , further comprising:

disposing the intravascular device in a cerebral venous sinus as the blood vessel.

7 . The method according to claim 1 , wherein the electrode is provided at a straight portion of the wire member.

8 . A method comprising:

disposing, in a cerebral blood vessel of an organism, an intravascular device including at least one electrode provided on a wire member; and

detecting activity of nerve tissue or stimulating of the nerve tissue with the electrode, the nerve tissue being positioned outside the blood vessel near the electrode,

wherein the wire member is formed from a single metal wire and an insulator covering the single metal wire.

9 . The method according to claim 8 , wherein the electrode is provided at a straight portion of the wire member.

10 . A method comprising:

disposing, in a cerebral blood vessel of an organism, an intravascular device including at least one electrode provided on a wire member; and

detecting activity of nerve tissue or stimulating of the nerve tissue with the electrode, the nerve tissue being positioned outside the blood vessel near the electrode,

wherein the wire member is formed from a single metal wire and an insulator covering the single metal wire, and

the electrode is provided both at a straight portion and a spiral portion of the wire member.