Assembly and method for the closure of vascular abnormalities
Described herein is a patch delivery assembly for treating a target site and a method for deploying the same. The patch delivery assembly includes a patch installation frame having a self-expanding body extending between a proximal end and an open distal end and defining a lumen therethrough. The patch delivery assembly also includes a delivery cable having a distal end coupled to the proximal end of the patch installation frame and further defining the lumen, and a securement device extending through the lumen defined through the delivery cable and the patch installation frame, the securement device terminating in a distal working end including a securement mechanism. In a deployment configuration of the patch delivery assembly, the patch delivery assembly further includes a patch releasably coupled to the distal end of the patch installation frame, for securement to tissue of the target site using the securement mechanism.
1 . A patch delivery assembly for treating a target site, the patch delivery assembly comprising:
a patch installation frame comprising a self-expanding body extending between a proximal end and an open distal end and defining a lumen therethrough;
a delivery cable having a distal end coupled to the proximal end of the patch installation frame and further defining the lumen; and
a securement device extending through the lumen defined through the delivery cable and the patch installation frame, the securement device terminating in a distal working end including a securement mechanism,
wherein, in a deployment configuration of the patch delivery assembly, the patch delivery assembly further comprises a patch releasably coupled to the distal end of the patch installation frame, for securement to tissue of the target site using the securement mechanism,
wherein the patch installation frame comprises a folded braided shape-memory material and has a tapered wall defining a cavity therein.
2 . The patch delivery assembly of claim 1 , wherein the patch comprises a flexible occlusive material.
3 . The patch delivery assembly of claim 1 , wherein the securement mechanism comprises one of a suture mechanism, an adhesive mechanism, and a staple mechanism.
4 . The patch delivery assembly of claim 1 , wherein a shape of the patch corresponds to a shape of the distal end of the patch installation frame.
5 . The patch delivery assembly of claim 1 , wherein the distal end of the patch installation frame is open and forms an opening which is free of a material forming the patch installation frame.
6 . The patch delivery assembly of claim 5 , wherein the distal end of the patch installation frame defines a securement path that is configured to confine operation of the securement mechanism therewithin.
7 . The patch delivery assembly of claim 1 , wherein the securement device is rotatable within a 360° range of motion.
8 . The patch delivery assembly of claim 1 , wherein the patch installation frame has a tapered cone shape with the patch installation frame tapering outwardly from the proximal end towards the distal end thereof.
9 . The patch delivery assembly of claim 1 , wherein a fold in the folded braided shape-memory material defines the distal end of the patch installation frame.
10 . The patch delivery assembly of claim 1 , wherein the folded braided shape-memory material forming the patch installation frame includes free ends at the proximal end of the patch installation frame, the free ends being welded, crimped, or adhered to prevent unraveling of the folded braided shape-memory material.
11 . The patch delivery assembly of claim 10 , wherein the free ends of the folded braided shape-memory material are coupled to an exterior surface of the delivery cable.
12 . A method of securing a patch to tissue at a target site, the method comprising:
positioning a patch delivery assembly at the target site, the patch delivery assembly including (i) a patch installation frame including a self-expanding body extending between a proximal end and an open distal end and defining a lumen therethrough, (ii) a delivery cable having a distal end coupled to the proximal end of the patch installation frame and further defining the lumen, and (iii) a securement device extending through the lumen defined through the delivery cable and the patch installation frame, the securement device terminating in a distal working end including a securement mechanism, wherein, in a deployment configuration of the patch delivery assembly, the patch delivery assembly further includes a patch releasably coupled to the distal end of the patch installation frame, wherein the patch installation frame comprises a folded braided shape-memory material and has a tapered wall defining a cavity therein;
deploying the patch installation frame from a delivery catheter, said deploying comprising (a) expanding the patch installation frame from a constricted delivery configuration to an expanded deployment configuration and (b) simultaneously expanding the patch coupled to the patch installation frame;
abutting the distal end of the patch installation frame and the patch against tissue at the target site;
securing the patch to the tissue using the securement mechanism; and
de-coupling the patch from the patch installation frame.
13 . The method of claim 12 , wherein said de-coupling the patch comprises trimming one or more suture materials coupling the patch to the distal end of the patch installation frame.
14 . The method of claim 12 , wherein said securing the patch comprises rotating the securement mechanism through a 360° securement path defined by the distal end of the patch installation frame.
15 . The method of claim 12 , wherein said securing the patch comprises one of suturing, adhering, and stapling the patch to the tissue using the securement mechanism.
16 . The method of claim 12 , further comprising withdrawing the patch delivery assembly from the target site while leaving the patch secured to the tissue at the target site.
17 . The method of claim 12 , further comprising verifying a position of the patch delivery assembly prior to said securing the patch.
18 . The method of claim 12 , further comprising coupling the patch to the patch installation frame prior to said positioning, said coupling comprising threading one or more suture materials about a circumference of the distal end of the patch installation frame and through the patch.
19 . The method of claim 12 , wherein said deploying the patch installation frame comprises proximally retracting the delivery catheter.
20 . The method of claim 12 , wherein said deploying the patch installation frame comprises distally advancing the delivery cable through the delivery catheter.