IP Library Granted Patent US 12667406
Granted Patent B2
US 12667406 · App. 17/096,061 · Granted Jun 30, 2026

Device for treating endometriosis

Inventors: Nikhil M. Murdeshwar (Maple Grove, MN); Thomas J. Holman (Princeton, MN)
Assignee: Gyrus ACMI, Inc.
A61B18/042A61B18/14A61B2018/00065A61B2018/00559A61B2018/00577A61B2018/00601A61B2018/1412
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Quick Facts
Patent No.
US 12667406
App. No.
17/096,061
Granted
Jun 30, 2026
Kind
B2
Abstract

An electrotherapeutic device can be configured for at least partial insertion into a patient. The device can include a shaft including a proximal portion and a distal portion, a gas-delivery lumen extending between the proximal portion and the distal portion of the shaft, and one or more electrodes located near the distal portion of the shaft. The electrodes can include a plasma activation electrode for generating plasma from gas delivered to the distal portion of the shaft via the gas-delivery lumen, and an ablation electrode for generating electromagnetic ablation energy. The medical device can be used in a method of treating endometriosis including delivering a gas toward an in vivo treatment site within a patient, generating plasma from the gas on or near the in vivo treatment site using a plasma activation electrode, exposing the treatment site to the plasma, and applying electromagnetic ablation energy to treat endometrial tissue.

Claims (26)

1 . An electrotherapeutic device for at least partial insertion into a patient, the device comprising:

a shaft including a proximal end portion and a distal end portion, the shaft defining a fluid-impervious gas-delivery lumen extending between the proximal end portion of the shaft, located at a handle connection, and the distal end portion of the shaft, the fluid-impervious gas-delivery lumen configured to deliver gas into the patient at the distal end portion of the shaft;

a plasma activation electrode configured to be actuatable for generating plasma from the gas, the plasma activation electrode extending through the fluid-impervious gas-delivery lumen and extendable distally outward from the shaft via a distal opening at the distal end portion of the fluid-impervious gas-delivery lumen;

an electromagnetic ablation electrode configured to be actuatable for generating electromagnetic ablation energy, the electromagnetic ablation electrode mounted in a fixed location on an external surface of the distal end portion of the shaft and offset from the plasma activation electrode; and

a shield, both lateral to and outside of both of the shaft and the fluid-impervious gas-delivery lumen, the shield configured to be translated longitudinally and independently from the electromagnetic ablation electrode to selectively physically shield a distal tip of the electromagnetic ablation electrode from plasma generated by the plasma activation electrode when the plasma generation electrode is extended distally outward from the shaft.

2 . The device of claim 1 , wherein the electromagnetic ablation electrode is configured to be actuatable for generating electromagnetic ablation energy in an absence of gas delivery.

3 . The device of claim 1 , further comprising a gas source fluidly connected to the shaft to permit gas from the gas source to travel toward the plasma activation electrode via the fluid-impervious gas-delivery lumen.

4 . The device of claim 1 , wherein the plasma activation electrode is separate from the electromagnetic ablation electrode.

5 . The device of claim 1 , wherein the plasma activation electrode is configured to provide plasma to treat a patient more globally than the electromagnetic ablation energy provided by the electromagnetic ablation electrode.

6 . The device of claim 1 , wherein the electromagnetic ablation electrode is actuatable over a local treatment site.

7 . The device of claim 1 , wherein the shaft comprises a width at the proximal portion, the width in a range of 1 mm to 5 mm, inclusive.

8 . The electrotherapeutic device of claim 1 , wherein the shaft is sized and shaped for insertion to a uterus through a cervix.

9 . The electrotherapeutic device of claim 1 , further comprising a handle connected to the proximal end portion of the shaft, the handle comprising a first trigger for receiving user input for actuating the plasma activation electrode and a second trigger for receiving user-input for actuating the electromagnetic ablation electrode.

10 . The electrotherapeutic device of claim 1 , wherein the device is configured to be switched between a first mode where the plasma activation electrode is actuatable, and a second mode where the electromagnetic ablation electrode is actuatable.

11 . An electrotherapeutic device for at least partial insertion into a patient, the device comprising:

a shaft including a proximal end portion and a distal end portion, the shaft defining a fluid-impervious gas-delivery lumen extending between the proximal end portion of the shaft, located at a handle connection, and the distal end portion of the shaft;

one or more plasma activation electrodes located near the distal end portion of the shaft, the one or more plasma activation electrodes configured to be actuatable for establishing a plasma from gas delivered to the distal end portion of the shaft via the fluid-impervious gas-delivery lumen

an electromagnetic ablation electrode configured to be actuatable for generating electromagnetic ablation energy, the electromagnetic ablation electrode mounted in a fixed location on an external surface of the distal end portion of the shaft and offset from the plasma activation electrode;

a shield, both lateral to and outside of both of the shaft and the fluid-impervious gas-delivery lumen, the shield configured to be translated longitudinally and independently from the electromagnetic ablation electrode to selectively physically shield a distal tip of the electromagenetic ablation electrode from plasma generated by the plasma activation electrode when the plasma generation electrode is extended distally outward from the shaft; and

a handle connected to the proximal end portion of the shaft, the handle comprising a first trigger for actuating the one or more plasma activation electrodes and a second trigger for actuating the one or more electromagnetic ablation electrodes.

12 . The device of claim 11 , wherein the electromagnetic ablation electrode is configured to generate AC electromagnetic ablation energy and the one or more plasma activation electrodes are configured to generate plasma from the gas.

13 . The device of claim 12 , wherein the at least two plasma activation electrodes are configured to each produce plasma.

14 . The device of claim 11 , wherein the one or more plasma activation electrodes comprise at least two plasma activation electrodes configured to produce plasma therebetween.

15 . The device of claim 11 , wherein the one or more plasma activation electrodes comprise a plasma activation electrode at least partially surrounded in a housing having a plurality of pores for passage of at least one of gas or plasma therethrough.

16 . The device of claim 11 , wherein the one or more plasma activation electrodes comprise a first plurality of plasma activation electrodes arranged in a first plane.

17 . The device of claim 16 , further comprising a second plurality of plasma activation electrodes arranged in a second plane parallel to the first plane.