Cryogenic process for making cannabinoid nanoparticles and compositions made thereby
The invention relates generally to a cryogenic process for making cannabinoid nanoparticles and compositions made thereby.
1 . A process for making cannabinoid nanoparticles, comprising: Delivering a homogenized cannabinoid emulsion entrained in cryogenic carrier fluid as a high speed stream to a nozzle within a collision chamber to collide the cryogenic cannabinoid stream with an impact surface to obtain cannabinoid nanoparticles as a slurry and collecting the cannabinoid nanoparticles, wherein the homogenized cannabinoid emulsion is obtained by mixing a cannabis extract, distillate, or isolate derived from hemp having less than 0.3% THC with aqueous surfactant and solvent to obtain a cannabinoid emulsion, and homogenizing the cannabinoid emulsion in a homogenizer to obtain a homogenized cannabinoid emulsion, and wherein the impact surface is a second nozzle delivering a second cryogenic cannabinoid stream under high speed to the collision chamber to collide the cryogenic cannabinoid stream with the second cryogenic cannabinoid stream to obtain cannabinoid nanoparticles.
2 . The process according to claim 1 , wherein the step of collecting cannabinoid nanoparticles from the collision chamber includes passing the collected cannabinoid nanoparticles through a nanofilter having a pore size less than 500 nm before depositing in the reservoir, and returning collected cannabinoid nanoparticles larger than 500 nm in a return stream to the cryogenic cannabinoid stream.
3 . The process according to claim 1 , wherein the step of collecting cannabinoid nanoparticles from the collision chamber includes passing the collected cannabinoid nanoparticles through a nanofilter having a pore size less than 100 nm before depositing in the reservoir, and returning collected cannabinoid nanoparticles larger than 100 nm in a return stream to the cryogenic cannabinoid stream.
4 . The process according to claim 1 , wherein the cannabis extract, distillate, or isolate derived from hemp having less than 0.3% THC is selected from the group consisting of: cannabis oil, hash oil, cannabis distillate, cannabis isolate, Cannabis flower essential oil, kief, hash, cannabis resin, cannabis wax, cannabis tincture, and mixtures or combinations containing the same.
5 . The process according to claim 1 , wherein the surfactant is selected from the group consisting of a nonionic surfactant, cationic surfactant, anionic surfactant, amphoteric surfactant, and a mixture or combination thereof.
6 . The process according to claim 1 , wherein the solvent is selected from the group consisting of water, ethanol, butane, propane, hexane, petroleum ether, methyl tertbutyl ether, diethyl ether, carbon dioxide (CO2), olive oil, and a mixture or combination thereof.