Inhaler device for inhalable liquids
The invention is directed to an inhaler device for inhalable liquids, in particular for the administration of inhalable volatile liquids such as halogenated volatile liquids, to a patient. According to particular embodiments, the inhaler device may include a liquid container for hermetically storing inhalable liquid; a wicking material for supporting inhalable liquid; a piercing member configured to pierce the liquid container, wherein the liquid container may be provided in a first position in which the piercing member does not engage the liquid container and inhalable liquid remains hermetically stored within the liquid container, and the liquid container may be displaced from the first position to a second position such that the piercing member pierces the liquid container to release inhalable liquid onto the wicking material, whereby during inhalation inhalable liquid vapor from the wicking material is delivered to the patient.
1 . An inhaler device for delivering an inhalable liquid to a patient, the inhaler device comprising:
a mouthpiece;
an air inlet;
a liquid container for hermetically storing inhalable liquid;
a wicking material for supporting inhalable liquid;
a piercing member configured to pierce the liquid container, the piercing member comprising one or more fluid channels arranged to enable liquid to drain from the liquid container through the piercing member; and
a first one-way valve configured to enable gas to flow into the mouthpiece during inhalation, and prevent gas from flowing in the opposite direction during exhalation;
wherein
the mouthpiece, the first one-wave valve, the wicking material, and the air inlet are fluidly connected to provide an inhalation chamber; and
the inhaler device is configured such that:
the liquid container may be provided in a first position in which the piercing member does not engage the liquid container and inhalable liquid remains hermetically stored within the liquid container;
the liquid container may be displaced from the first position to a second position such that the piercing member pierces the liquid container to release inhalable liquid onto the wicking material through the piercing member, whereby during inhalation air entering the air inlet flows through the inhalation chamber to deliver inhalable liquid vapor from the wicking material to the patient via the mouthpiece; and
the wicking material is spaced from the piercing member to allow passage of air through the at least one channel into the liquid container, thereby preventing or reducing an air-lock from restricting release of inhalable liquid from the liquid container.
2 . The inhaler device according to claim 1 , and further comprising: a return air chamber in fluid communication with a second one-way valve, such that during inhalation the first one-way valve is open and the second one way valve is closed, and during exhalation the first one way valve is closed and the second one-way valve is open to enable exhaled air to flow from the mouthpiece through the return air chamber.
3 . The inhaler device according to claim 2 , wherein the return air chamber comprises filtering material configured to filter volatile liquid vapor from the exhaled breath of a patient upon exhalation.
4 . The inhaler device according to claim 3 , wherein the filtering material comprises activated carbon.
5 . The inhaler device according to claim 1 , wherein the liquid container contains a halogenated volatile liquid.
6 . The inhaler device according to claim 5 , wherein the halogenated volatile liquid is selected from the group consisting of halothane (2-bromo-2-chloro-1,1,1-trifluoroethane), sevoflurane (fluoromethyl-2,2,2-trifluoro-1-(trifluroromethyl)ethyl ether), desflurane (2-difluoromethyl-1,2,2,2-tetrafluoroethrylether), isoflurane (1-chloro-2,2,2-trifluoroethyldifluoromethyl ether), enflurane (2-chloro-1,1,2-trifluoroethyldifluoromethyl ether) and methoxyflurane (2,2-dichloro-1,1-difluoroethylmethyl ether).
7 . The inhaler device according to claim 6 , wherein the halogenated volatile liquid is methoxyflurane.
8 . The inhaler device according to claim 1 , wherein the inhaler device comprises spacer tabs configured to space the wicking material from the piercing member.
9 . The inhaler device according to claim 1 , wherein the wicking material and/or the piercing member remains stationary within the inhaler device while the liquid container is displaced from the first position to the second position.
10 . The inhaler device according to claim 1 , wherein the liquid container comprises only a single region configured to be pieced.
11 . The inhaler device according to claim 1 , wherein the inhaler deviceis configured to enable air to pass by or around the liquid container.
12 . The inhaler device according to claim 1 , wherein the inhaler device comprises a diluter hole positioned to enable a portion of inhalation air to bypass the wicking material before passing into the mouthpiece.
13 . The inhaler device according to claim 12 , wherein the diluter hole is positioned and configured to enable the patient to restrict or block the diluter hole with a finger.
14 . The inhaler device according to claim 1 , wherein the mouthpiece comprises a filter configured to reduce or prevent inhalation of liquid droplets by the patient.
15 . The inhaler device according to claim 14 , wherein the filter is formed of a polymeric non-woven material.
16 . The inhaler device according to claim 1 , wherein the inhaler deviceis configured to enable replacement of the liquid container and/or the wicking material.
17 . The inhaler device according to claim 1 , wherein the wicking material is configured to enable inhalation air to pass through and along multiple surfaces of the wicking material.
18 . The inhaler device according to claim 1 , wherein the inhaler device is configured prevent air from passing through the liquid container.