Methods for removing clot material from within a body

Inventors: Vahid Saadat (Atherton, CA); William Jason Fox (San Mateo, CA); Neekon Saadat (Atherton, CA); Mojgan Saadat (Atherton, CA); Mahyar Z. Kermani (San Ramon, CA); Michael Pare (Atherton, CA)

Assignee: Inquis Medical, Inc.

A61M25/01 A61B17/22 A61B17/3207 A61B17/320783 A61B2017/00026 A61B2017/00039 A61B2017/00119 A61B2017/22079 A61B2217/005

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Quick Facts

Patent No.: US 12667695
App. No.: 18/935,426
Granted: Jun 30, 2026
Kind: B2

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Abstract

Described here are methods of removing a clot material from within a body including advancing a catheter through a vessel of the body, sensing (using one or more sensors on a distal end region of the catheter) a preexisting clot material within an extraction zone external and adjacent to a clot removal orifice on the distal end region of the catheter and drawing the clot material into the catheter through the clot removal orifice. The one or more sensors may comprise a pair of electrodes in contact with the clot removal orifice that are configured as an impedance sensor. The extraction zone may extend externally 0-5 cm from a clot removal orifice on the distal end region of the catheter.

Claims (28)

1 . A method of removing a clot material from within a body, the method comprising:

advancing a catheter through a vessel of the body;

sensing, using one or more sensors on a distal end region of the catheter, a preexisting clot material within an extraction zone external and adjacent to a clot removal orifice on the distal end region of the catheter, wherein the one or more sensors comprises a pair of electrodes in contact with the clot removal orifice that are configured as an impedance sensor; and

drawing the clot material into the catheter through the clot removal orifice.

2 . The method of claim 1 , wherein the extraction zone is between 0-5 cm of the clot removal orifice.

3 . The method of claim 1 , wherein sensing comprises using the pair of electrodes to sense the preexisting clot material based on an impedance signal.

4 . The method of claim 1 , wherein sensing further comprises using one or more of: a second impedance sensor to sense the preexisting clot material, an optical sensor to sense the preexisting clot material, a mechanical sensor to sense the preexisting clot material, and/or an ultrasound transducer to sense the preexisting clot material.

5 . The method of claim 1 , wherein sensing comprises providing a visual output of the clot material.

6 . The method of claim 1 , wherein the clot removal orifice is positioned on a lateral side of the distal end region of the catheter.

7 . The method of claim 1 , wherein the clot removal orifice is on a tapered side of the distal end region of the catheter.

8 . The method of claim 1 , wherein drawing the clot material into the catheter comprises applying suction to aspirate the clot material into the clot removal orifice, wherein the clot removal orifice is fluidly connected to an aspiration lumen.

9 . The method of claim 1 , wherein drawing the clot material into the catheter comprises mechanically removing the clot material.

10 . The method of claim 1 , wherein drawing the clot material into the catheter comprises automatically removing the clot material after sensing preexisting clot material within the extraction zone.

11 . The method of claim 1 , further comprising alerting a user that clot material is within the extraction zone adjacent to the clot removal orifice.

12 . A method of removing a clot material from within a body, the method comprising:

advancing a catheter through a vessel of the body;

sensing, using one or more impedance sensors on a distal end region of the catheter, that a preexisting clot material is within an extraction zone that is external and adjacent to a clot removal orifice on the distal end region of the catheter, wherein the one or more impedance sensors comprises one or more electrodes in contact with the clot removal orifice; and

applying suction to draw the clot material into the catheter through the clot removal orifice after sensing the preexisting clot material within the extraction zone.

13 . The method of claim 12 , wherein the extraction zone is between 0-5 cm of the clot removal orifice.

14 . The method of claim 12 , wherein the one or more electrodes comprises a pair of electrodes positioned at the clot removal orifice.

15 . The method of claim 12 , wherein the clot removal orifice is positioned on a lateral side of the distal end region of the catheter.

16 . The method of claim 12 , wherein the clot removal orifice is on a tapered side of the distal end region of the catheter.

17 . The method of claim 12 , further comprising alerting a user that clot material is within the extraction zone adjacent to the clot removal orifice.

18 . The method of claim 12 , wherein applying suction to draw the clot material into the catheter through the clot removal orifice after sensing the preexisting clot material within the extraction zone comprises automatically applying suction.

19 . A method of removing a clot material from within a body, the method comprising:

advancing a catheter through a vessel of the body;

sensing, using one or more impedance sensors on a distal end region of the catheter, that a preexisting clot material is within an extraction zone extending externally 0-5 cm from a clot removal orifice on the distal end region of the catheter, wherein the one or more impedance sensors comprises one or more electrodes in contact with the clot removal orifice; and

applying suction to draw the clot material into the catheter through the clot removal orifice after sensing the preexisting clot material within the extraction zone.