Antibacterial polymer composition
The present disclosure relates to an antibacterial polymer composition, and more particularly, to an antibacterial polymer composition that enables the preparation of a coating layer exhibiting excellent antibacterial properties.
1 . An antibacterial polymer composition comprising:
a hydrophilic polymer;
an antibacterial polymer that is a copolymer containing a repeating unit represented by Chemical Formula 1and a repeating unit represented by Chemical Formula 2; and
a solvent containing water,
wherein the antibacterial polymer composition has a viscosity under a constant temperature/humidity condition (23° C., 50% relative humidity) of 1,500 cP to 3,000 cP as measured using a Brookfield DV2T LV TJ0 viscometer with V-75 spindle at 200 rpm,
wherein the antibacterial polymer composition has a bacterial growth inhibition rate against Proteus mirabilis of 60% or more as calculated by Equation 1:
Bacterial
growth
inhibition
rate
(
%
)
=
(
1
-
A
S
A
0
)
×
100
[
Equation
1
]
wherein, A s is an absorbance of an experimental group at 600 nm wavelength of Proteus mirabilis culture medium to which a sample is added, and A 0 is an absorbance of a control group at 600 nm wavelength of the Proteus mirabilis culture medium to which the sample is not added,
the experimental group is prepared by:
applying the antibacterial polymer composition onto a release-treated PET film substrate so as to have a thickness of 200 μm using a bar coater, and then drying at 80° C. for 240 minutes to prepare an antibacterial film having a coating layer formed on one side of the substrate, and
transferring 25 ml of broth type medium inoculated with Proteus Mirabilis at 3300 CFU/ml to a 50 mL conical tube, to which 0.1 g of the antibacterial film prepared is cut and added with alcohol-sterilized scissors, vortexing, and incubating in a shaking incubator at 37° C. for 16 hours, and
the control group is prepared by culturing Proteus Mirabilis at 37° C. for 16 hours:
in Chemical Formula 1,
L is an alkylene having 1 to 10 carbon atoms,
R 1 to R 3 are each independently hydrogen or methyl;
one of R 4 to R 6 is an alkyl having 5 to 20 carbon atoms, and the rest of R 4 to R 6 are each independently an alkyl having 1 to 4 carbon atoms,
X is halogen, and
n is an integer of 10 to 10,000,
in Chemical Formula 2,
R′ 1 to R′ 3 are each independently hydrogen or methyl, and
m is an integer of 1 or more.
2 . The antibacterial polymer composition of claim 1 , wherein:
the hydrophilic polymer is at least one selected from the group consisting of polyvinyl alcohol (PVA), polyethylene glycol (PEG), polyvinylpyrrolidone (PVP) and carboxymethyl cellulose (CMC).
3 . The antibacterial polymer composition of claim 1 , wherein:
the antibacterial polymer is contained in an amount of 1 part by weight or more and less than 50 parts by weight with respect to 100 parts by weight of the hydrophilic polymer.
4 . The antibacterial polymer composition of claim 1 , wherein:
in Chemical Formula 1,
L is methylene, ethylene, or propylene.
5 . The antibacterial polymer composition of claim 1 , wherein:
in Chemical Formula 1,
R 1 is hydrogen or methyl, R 2 and R 3 are hydrogen, one of R 4 to R 6 is an alkyl having 10 to 20 carbon atoms, and the rest of R 4 to R 6 are methyl, ethyl, propyl or butyl.
6 . The antibacterial polymer composition of claim 1 , wherein:
the repeating unit represented by Chemical Formula 1 is represented by any one of the following Chemical Formulas 1-1 to 1-4:
in Chemical Formula 1-1,
a is an integer of 2 to 9,
X is halogen,
n is an integer of 10 to 10,000,
in Chemical Formula 1-2,
b is an integer of 2 to 9,
X is halogen,
n is an integer of 10 to 10,000,
in Chemical Formula 1-3,
c is an integer of 2 to 9,
X is halogen,
n is an integer of 10 to 10,000,
in Chemical Formula 1-4,
d is an integer of 2 to 9,
X is halogen, and
n is an integer of 10 to 10,000.
7 . The antibacterial polymer composition of claim 1 , wherein:
when the antibacterial polymer is a copolymer further containing the repeating unit represented by Chemical Formula 2, a molar ratio of the repeating unit represented by Chemical Formula 1 to the repeating unit represented by Chemical Formula 2 is 1:0.01 to 1:100.
8 . The antibacterial polymer composition of claim 1 , wherein:
the repeating unit represented by Chemical Formula 2 is represented by the following Chemical Formula 2-1:
in Chemical Formula 2-1,
m is an integer of 1 or more.
9 . The antibacterial polymer composition of claim 1 , wherein:
the antibacterial polymer has a weight average molecular weight of 10,000 to 1,000,000 g/mol.
10 . The antibacterial polymer composition of claim 1 , wherein:
the solvent is water or a mixture of water and ethanol.
11 . The antibacterial polymer composition of claim 1 , wherein:
the antibacterial polymer composition has a solid content of 5 to 50% by weight.
12 . The antibacterial polymer composition of claim 1 , wherein:
the antibacterial polymer composition exhibits antibacterial activity against at least one of Gram-negative bacteria and Gram-positive bacteria.
13 . The antibacterial polymer composition of claim 12 , wherein:
the Gram-negative bacteria is Proteus mirabilis , or Escherichia coli , and
the Gram-positive bacteria is Enterococcus faecalis.
14 . The antibacterial polymer composition of claim 12 , wherein:
the antibacterial polymer composition exhibits antibacterial activity against both Gram-negative bacteria and Gram-positive bacteria.
15 . An antibacterial article comprising:
a substrate; and
a coating layer provided on at least one surface on the substrate,
wherein the coating layer is formed by the antibacterial polymer composition according to claim 1 .