IP Library › Granted Patent US 12673009
Granted Patent B2
US 12673009 · App. 18/011,791 · Granted Jul 7, 2026

Dental material

Inventors: Paul Thomas Sharpe (London, GB); Eileen Deirdre Gentleman (London, GB); Delia Silke Brauer (Jena, DE)
Assignees: King's College London; Friedrich-Schiller-Universität Jena
A61K6/77
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Quick Facts
Patent No.
US 12673009
App. No.
18/011,791
Filed
Dec 20, 2022
Granted
Jul 7, 2026
Kind
B2
Art Unit
1767
USPC
523/116
Abstract

A dental filling material or precursor thereof for use in therapy, which material comprises lithium and is capable of releasing lithium under physiological conditions.

Claims (19)

1 . A method of dentistry comprising administering a single dental filling material or precursor thereof to a subject in need thereof, wherein said dental filling material both stimulates dentine regeneration and provides a filling in the cavity at the same time, said dental filling material comprises lithium and said dental filling material is configured to release the lithium under physiological conditions, and wherein said method of dentistry comprises the treatment of a dental lesion, wherein the pulp is not exposed.

2 . The method according to claim 1 , wherein said method of dentistry comprises dentine repair.

3 . The method according to claim 1 , wherein said method of dentistry comprises the treatment of a dental lesion, wherein dentine is exposed but the pulp is not exposed.

4 . The method according to claim 1 , wherein the dental filling material or precursor thereof comprises a bioactive glass comprising lithium.

5 . The method according to claim 4 , wherein the bioactive glass comprises a source of lithium at a molar percentage of at least 1%.

6 . The method according to claim 4 , wherein the bioactive glass comprises Li 2 O.

7 . The method according to claim 4 , wherein the bioactive glass comprises Li 2 O at a molar percentage of from 5 to 30%.

8 . The method according to claim 1 , wherein the dental filling material comprises a dental cement comprising lithium.

9 . The method according to claim 8 , wherein the dental cement is a glass ionomer cement comprising lithium.

10 . The method according to claim 8 , wherein the dental cement comprises a bioactive glass comprising lithium.

11 . The method according to claim 10 , wherein the bioactive glass is a bioactive glass comprising a source of lithium at a molar percentage of at least 1%.

12 . The method according to claim 6 , wherein the dental filling material or precursor thereof comprises the bioactive glass in an amount of at least 1 wt %.

13 . The method of claim 4 , wherein the dental filling material or precursor thereof comprises a glass component comprising the bioactive glass comprising lithium.

14 . The method of claim 13 , wherein the dental filling material or precursor thereof comprises the glass component in an amount of at least 10 wt %.

15 . The method of claim 13 , wherein the glass component comprises the bioactive glass in an amount of at least 1 wt %.

16 . The method of claim 1 , wherein a precursor of the dental filling material is administered.

17 . The method according to claim 16 , wherein the precursor is a dry precursor.

18 . The method according to claim 16 , wherein the precursor comprises a powder.

19 . The method according to claim 16 , wherein the precursor is provided in the form of a capsule, which capsule further comprises a liquid.