IP Library Granted Patent US 12673018
Granted Patent B2
US 12673018 · App. 18/559,989 · Granted Jul 7, 2026

Hyaluronate skin-penetrating cosmetic

Inventors: Mika Yoshimura (Tokyo, JP); Anna Okishima (Tokyo, JP); Takashi Oka (Tokyo, JP); Hiroko Shimizu (Tokyo, JP)
Assignee: Shiseido Company, Ltd.
A61K8/735A61Q19/007A61K2800/5428
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Quick Facts
Patent No.
US 12673018
App. No.
18/559,989
Granted
Jul 7, 2026
Kind
B2
Abstract

To provide a hyaluronate skin-penetrating cosmetic that allows a hyaluronate to penetrate into the skin without a complicated step such as composite formation of a hyaluronate. A hyaluronate skin-penetrating cosmetic of the present disclosure contains a hyaluronate and an amphoteric surfactant.

Claims (12)

1 . A hyaluronate skin-penetrating cosmetic, comprising

a hyaluronate and an amphoteric surfactant,

wherein the weight-average molecular weight of the hyaluronate is 300,000 or more, and wherein the hyaluronate does not contain hyaluronate derivatives, and

wherein the amphoteric surfactant comprises at least one selected from the group consisting of betaine-type amphoteric surfactants, amino acid-type amphoteric surfactants, sulfonic acid-type amphoteric surfactants, sulfate-type amphoteric surfactants, and lecithin.

2 . The cosmetic according to claim 1 , comprising a salt at a concentration giving an ionic strength of 0.05 or more.

3 . The cosmetic according to claim 1 , wherein the content of the amphoteric surfactant is 0.01% by mass or more with respect to a total amount of the cosmetic.

4 . The cosmetic according to claim 2 , wherein the salt is at least one selected from the group consisting of monovalent salts, divalent salts, and trivalent salts.

5 . The cosmetic according to claim 2 , wherein the salt is at least one selected from the group consisting of a sodium salt and a magnesium salt.

6 . The cosmetic according to claim 5 , wherein the sodium salt is sodium chloride, and the magnesium salt is magnesium chloride.

7 . The cosmetic according to claim 1 , comprising at least one moisturizing agent selected from the group consisting of propylene glycol, dipropylene glycol, and PEG/PPG-17/4 dimethyl ether.

8 . The cosmetic according to claim 7 , comprising sodium chloride.

9 . The cosmetic according to claim 1 , wherein the amphoteric surfactant comprises lecithin.