Use of caviar extracts
A method for the expression and/or for the amplification of the expression of thrombospondin-1, fibronectin, vimentin and/or mimecan in human skin. the method comprises applying to human skin at least one caviar extract which is capable of causing the expression and/or the amplification of the expression of thrombospondin-1, fibronectin, vimentin and/or mimecan in human skin.
1 . A method for the expression and/or for the amplification of the expression of thrombospondin-1, fibronectin, vimentin and/or mimecan in human skin, wherein the method comprises applying to human skin at least one caviar extract in an amount which is capable of causing at least one of the expression and the amplification of the expression of at least one of thrombospondin-1, fibronectin, vimentin, and mimecan in human skin.
2 . The method of claim 1 , wherein a cosmetic preparation comprising the at least one caviar extract is applied to the human skin.
3 . The method of claim 1 , wherein at least one of thrombospondin-1, fibronectin, vimentin and/or mimecan is caused to be expressed in human skin.
4 . The method of claim 1 , wherein the at least one caviar extract has been obtained from fish eggs of white sturgeon (Acipenser transmontanus) and/or of Siberian sturgeon (Acipenser baerii).
5 . The method of claim 1 , wherein the at least one caviar extract has been obtained by a process comprising
(1) homogenizing provided fish eggs in at least one solvent,
(2) extracting at least one liquid phase from the homogenizate obtained in (1), and
(3) optionally filtering the extract obtained in (2).
6 . The method of claim 5 , wherein at least one caviar extract is used, in a preparation of which at least water, but no glycol, or glycol in ratios by weight of water to glycol of from 1.1:1.0 to 1000:1.0, is added as solvent during the homogenization of the fish eggs and in which an aqueous phase of the homogenizate is extracted to obtain the at least one caviar extract.
7 . The method of claim 5 , wherein at least one caviar extract is used, in the preparation of which at least glycol and optionally water are added as solvent during the homogenization of the fish eggs, where a ratio by weight of water to glycol is from 1.0:1.0 to 1.0:1000, and in which a glycolic phase of the homogenizate is extracted to obtain the at least one caviar extract.
8 . The method of claim 5 , wherein at least one caviar extract is used, in the preparation of which at least one oil is added as solvent during the homogenization of the fish eggs and in which an oil phase is extracted.
9 . The method of claim 8 , wherein, as oil, triglycerides are used.
10 . The method of claim 8 , wherein a ratio by weight of the fish eggs to the added oil phase during the homogenization is from 1.0:0.1 to 1.0:1.0.
11 . The method of claim 6 , wherein a ratio by weight of the fish eggs to aqueous phase, when present, is from 1.0:10 to 1.0:1.0.
12 . The method of claim 7 , wherein a ratio by weight of the fish eggs to aqueous phase, when present, is from 1.0:10 to 1.0:1.0.
13 . The method of claim 1 , wherein mannose phosphate is additionally employed.
14 . The method of claim 1 , wherein mannose is additionally employed.
15 . The method of claim 1 , wherein at least two different caviar extracts are employed.
16 . The method of claim 1 , wherein at least three different caviar extracts are employed.
17 . The method of claim 16 , wherein there are employed
a first lipophilic caviar extract, in the preparation of which at least one oil is added as solvent during a homogenization of the fish eggs and in which an oil phase is extracted to obtain a lipophilic caviar extract,
a second aqueous caviar extract, in the preparation of which at least water, but no glycol, is added as solvent during a homogenization of the fish eggs and in which an aqueous phase is extracted to obtain the aqueous caviar extract, and
a third glycolic caviar extract, in the preparation of which at least glycol is added as solvent during a homogenization of the fish eggs and in which a glycolic phase is extracted to obtain the third caviar extract.
18 . A method of reinforcing at least one of the skin ligaments, the retinacula cutis, and the connective tissue strands in human skin, wherein the method comprises applying at least one caviar extract in an amount which is capable of reinforcing at least one of the skin ligaments, the retinacula cutis, and the connective tissue strands in human skin to human skin.
19 . The method of claim 1 , wherein sodium mannose phosphate is additionally employed.
20 . The method of claim 1 , wherein the at least one caviar extract is capable of causing at least one of the expression and the amplification of the expression of at least one of thrombospondin-1, vimentin, and mimecan in human skin.