Anti-inflammatory composition and method of treatment
The anti-inflammatory composition may be administered to a subject in need thereof to prevent or reduce inflammation, including inflammation resulting from asthma. The anti-inflammatory composition may comprise both onion bulb extract and one or more glucocorticosteroids, particularly a low-dose glucocorticosteroid. The anti-inflammatory composition may be administered to a subject at risk of developing asthma to prevent the progression of asthma. The anti-inflammatory composition may act by reducing pEGFR levels, or by inhibiting other inflammatory pathways.
1 . A method of reducing inflammation in an asthmatic patient, comprising the step of administering an anti-inflammatory composition including 30 mg/kg onion bulb (OBE) and 0.5 mg/kg dexamethasone in a single composition to the patient, wherein the anti-inflammatory composition is a single composition which is administered to the patient to achieve a synergistic effect from said single composition such that a reduced dosage amount of the dexamethasone is more effective as an anti-inflammatory treatment for the patient as compared to a dosage amount of the dexamethasone when administered alone.
2 . The method of reducing inflammation according to claim 1 , wherein the onion bulb extract comprises red onion bulb extracted in an organic solvent.
3 . The method of reducing inflammation according to claim 1 , wherein the onion blub extract comprises an extract of Allium cepa.
4 . A method of treating asthma, comprising the step of administering an anti-inflammatory composition including 30 mg/kg onion bulb (OBE) and 0.5 mg/kg dexamethasone in a single composition to a subject, wherein the anti-inflammatory composition is a single composition which is administered to the subject to achieve a synergistic effect from said single composition such that a reduced dosage amount of the dexamethasone is more effective as an anti-inflammatory treatment for the subject as compared to a dosage amount of the dexamethasone when administered alone.