Lactobactilus plantarum 2830 (ECGC 13110402) for use in treatments
The present invention relates to one or more strains of Lactobacilli and a cholesterol modifying agent (such as an oligosaccharide) for use in modifying the absorption of cholesterol in an individual or the treatment of heart disease, diabetes or obesity.
1 . A composition comprising a strain of Lactobacilli having an elevated bile salt hydrolase activity and a galactooligosaccharide; wherein the strain is Lactobacillus plantarum 2830 (ECGC 13110402),
wherein the galactooligosaccharide is produced by the strain by reverse β-galactosidase reaction, and wherein
the composition further comprises an excipient and/or carrier compound;
the composition is in the form of a food stuff or a food additive;
the Lactobacillus plantarum 2830 is freeze-dried;
the composition further comprises at least one selected from: vitamins, minerals, phytochemicals and/or antioxidants; or
a combination thereof.
2 . The composition of claim 1 for modifying the absorption of cholesterol in an individual.
3 . The composition of claim 1 for treatment of high cholesterol, heart disease, diabetes or obesity.
4 . The composition of claim 1 , wherein the galactooligosaccharide comprises a selective growth medium for the strain of Lactobacilli.
5 . The composition of claim 1 , wherein the composition is encapsulated.
6 . The composition of claim 1 , in the form of a foodstuff and/or for use as a dietary supplement.
7 . The composition of claim 1 , further comprising a prebiotic.
8 . A method of producing a composition, the method comprising: mixing a composition according to claim 1 with a cholesterol modifying agent in a biologically effective amount.