Compositions comprising an American cranberry extract and phospholipids
The present invention relates to compositions comprising an American cranberry extract combined with phospholipids, and the use thereof in the prevention and treatment of urinary tract infections. The invention also relates to processes for the preparation of said compositions, and formulations for oral administration comprising said compositions.
1 . A method for treating infections of the lower urinary tract in a patient in need thereof, said method comprising administering to said patient a formulation comprising:
a) 30 to 80 mg of Vaccinium macrocarpon extract corresponding to a proanthocyanidin daily intake ranging from 9 mg and 25 mg per dose; and at least one phospholipid in a weight ratio between Vaccinium macrocarpon extract and phospholipid ranging between 1:1 and 1:4; and
b) 120 mg of Vaccinium macrocarpon extract not combined with phospholipids said Vaccinium macrocarpon extract containing 30% proanthocyanidins amounting to 36 mg.
2 . The method according to claim 1 , wherein the composition further comprises one or more technological adjuvants selected from water-soluble or water-insoluble diluents, lubricants and/or glidants and surfactants.
3 . The method according to claim 2 , wherein the diluent is not a maltodextrin, mannitol, isomalt or a combination thereof.