IP Library › Granted Patent US 12673978
Granted Patent B2
US 12673978 · App. 17/780,188 · Granted Jul 7, 2026

Increasing resistance against fungal infections in plants

Inventors: Petra Epple; Brody John DeYoung (Research Triangle Park, NC); Holger Schultheiss (Limburgerhof, DE); Ralf Flachmann (Limburgerhof, DE); David A. Hubert (Durham, NC); Anne-Christina Herwig (Limburgerhof, DE)
Assignee: BASF SE
C07K14/415A01H6/20A01H6/46A01H6/54
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Quick Facts
Patent No.
US 12673978
App. No.
17/780,188
Granted
Jul 7, 2026
Kind
B2
Abstract

The present invention relates to a method of conferring or increasing resistance against fungal pathogens in plants, plant parts, and/or plant cells. To this end the invention focuses on facilitating or increasing the production and/or accumulation of a Myb41-type transcription factor (Myb41), fragment or homolog thereof in a plant, plant part and/or plant cell compared to corresponding wild type plants, wild type plant parts and/or wild type plant cells. The invention also relates to plants, plant parts, and/or plant cells having an increased resistance against fungal pathogens and to material and methods to create or use such plants plant parts or to produce products therefrom.

Claims (6)

1 . A method for reducing or delaying Phakopsora infection in a soybean plant, a soybean plant part, or a soybean plant cell, the method comprising:

(1) providing a transgenic soybean plant, transgenic soybean plant part, or transgenic soybean plant cell with an exogenous nucleic acid encoding a Myb41 protein having an amino acid sequence with at least 90% identity with SEQ ID NO. 2 or 5, wherein expression of the Myb41 protein confers increased resistance against Phakopsora thereto in comparison to a wild type soybean plant, wild type soybean plant part or wild type soybean plant cell; and

(2) growing the transgenic soybean plant, transgenic soybean plant part, or transgenic soybean plant cell in the presence of a fungal pathogen of the genus Phakopsora , wherein Phakopsora infection is reduced or delayed in the transgenic soybean plant, transgenic soybean plant part, or transgenic soybean plant cell as compared to a wild type soybean plant, wild type soybean plant part, or wild type soybean plant cell.

2 . The method according to claim 1 , further comprising the step of phosphorylating the Myb41 protein in the respective plant, plant part, or plant cell.

3 . The method according to claim 1 , wherein the Myb41 protein comprises a phosphomimetic mutation.

4 . The method according to claim 1 , wherein the Myb41 protein has an amino acid sequence with at least 95% identity to SEQ ID NO. 2 or 5.