IP Library Granted Patent US 12678091
Granted Patent B2
US 12678091 · App. 18/711,052 · Granted Jul 14, 2026

Perfusion imaging-based non-contact autonomic nervous system response multi-dimensional bio-signal measurement system and method

Inventor: Jong-Ha Lee (Daegu, KR)
Assignee: INDUSTRY ACADEMIC COOPERATION FOUNDATION KEIMYUNG UNIVERSITY
A61B5/4035A61B5/0205A61B5/0261A61B5/14551A61B5/021A61B5/02427
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Quick Facts
Patent No.
US 12678091
App. No.
18/711,052
Granted
Jul 14, 2026
Kind
B2
Abstract

Proposed are a perfusion imaging-based non-contact autonomic nervous system response multi-dimensional bio-signal measurement system and method, the system including a light source, a multi-dimensional multi-spectral camera, and a measurement diagnosis part. The light source is configured to emit light outside a visible light region, for measuring a multi-dimensional bio-signal in a non-contact manner. The multi-dimensional multi-spectral camera is configured to photograph amplified reflected light reflected after emitted from the light source and generate an image sequence of the bio-signal accordingly. The measurement diagnosis part is configured to measure heart rate, oxygen saturation, blood flow per second, and blood pressure through image processing of the image sequence of the bio-signal generated from photographing by the multi-dimensional multi-spectral camera.

Claims (35)

1 . A perfusion imaging-based non-contact autonomic nervous system response multi-dimensional bio-signal measurement system, comprising:

a light source configured to emit in at least two different wavelengths, for measuring a multi-dimensional bio-signal in a non-contact manner;

a multi-dimensional multi-spectral camera configured to photograph amplified reflected light reflected after emission from the light source, and generate an image sequence of the bio-signal; and

a processor configured to receive the image sequence from the multi-dimensional multi-spectral camera and to: measure heart rate, oxygen saturation, blood flow per second, and blood pressure through image processing of the image sequence; generate a high-resolution image by superimposing low-resolution images included in the image sequence; track contour feature points in the high-resolution image to determine perfusion diffusion time; and calculate the blood pressure using diffusion vector mean, the heart rate, the oxygen saturation, and perfusion amplitude.

2 . The perfusion imaging-based non-contact autonomic nervous system response multi-dimensional bio-signal measurement system of claim 1 ,

wherein the light source is configured to emit the light at about 765 nm and about 880 nm.

3 . The perfusion imaging-based non-contact autonomic nervous system response multi-dimensional bio-signal measurement system of claim 2 ,

wherein the light source comprises a first LED configured to emit red light and a second LED configured to emit infrared light.

4 . The perfusion imaging-based non-contact autonomic nervous system response multi-dimensional bio-signal measurement system of claim 1 ,

wherein the multi-dimensional multi-spectral camera is an infrared camera.

5 . The perfusion imaging-based non-contact autonomic nervous system response multi-dimensional bio-signal measurement system of claim 1 ,

wherein the processor is configured to measure the heart rate by extracting valid pixels through clustering from the image sequence.

6 . The perfusion imaging-based non-contact autonomic nervous system response multi-dimensional bio-signal measurement system of claim 5 ,

wherein the processor is configured to measure the oxygen saturation by using the image sequence obtained as the light is emitted alternately from the first LED and the second LED and is reflected.

7 . The perfusion imaging-based non-contact autonomic nervous system response multi-dimensional bio-signal measurement system of claim 6 ,

wherein the processor is configured to measure the blood pressure without physical contact by using the measured heart rate, the measured oxygen saturation, and a change in the blood flow per second measured through a deep neural network based on a measured amount of reflected light.

8 . A perfusion imaging-based non-contact autonomic nervous system response multi-dimensional bio-signal measurement method, comprising:

emitting, by a light source, light in at least two different wavelengths for measuring a multi-dimensional bio-signal in a non-contact manner;

photographing, by a multi-dimensional multi-spectral camera, amplified reflected light reflected after emission from the light source, and generating an image sequence of the bio-signal; and

processing, by a processor, the image sequence to:

measure heart rate, oxygen saturation, blood flow per second, and blood pressure through image processing of the image sequence; generate a high-resolution image by superimposing low-resolution images included in the image sequence;

track contour feature points in the high-resolution image to determine perfusion diffusion time; and

calculate the blood pressure using a diffusion vector mean, the heart rate, the oxygen saturation, and perfusion amplitude.

9 . The perfusion imaging-based non-contact autonomic nervous system response multi-dimensional bio-signal measurement method of claim 8 ,

wherein the light is emitted at about 765 nm and about 880 nm.

10 . The perfusion imaging-based non-contact autonomic nervous system response multi-dimensional bio-signal measurement method of claim 9 ,

wherein the light source comprises a first LED configured to emit red light and a second LED configured to emit infrared light.

11 . The perfusion imaging-based non-contact autonomic nervous system response multi-dimensional bio-signal measurement method of claim 8 ,

wherein the multi-dimensional multi-spectral camera is an infrared camera.

12 . The perfusion imaging-based non-contact autonomic nervous system response multi-dimensional bio-signal measurement method of claim 8 ,

wherein the heart rate is measured by extracting valid pixels through clustering from the image sequence.

13 . The perfusion imaging-based non-contact autonomic nervous system response multi-dimensional bio-signal measurement method of claim 12 ,

wherein the oxygen saturation is measured by using the image sequence obtained as the light is emitted alternately from the first LED and the second LED and is reflected.

14 . The perfusion imaging-based non-contact autonomic nervous system response multi-dimensional bio-signal measurement method of claim 13 ,

wherein the blood pressure is measured without physical contact by using the measured heart rate, the measured oxygen saturation, and a change in the blood flow per second measured through a deep neural network based on a measured amount of reflected light.