IP Library Granted Patent US 12678272
Granted Patent B2
US 12678272 · App. 18/668,824 · Granted Jul 14, 2026

Oral appliance in a blockchain system

Inventor: Peter John Zegarelli (Sleepy Hollow, NY)
Assignee: Emanate Biomedical, Inc.
A61C19/066A61C5/90
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Quick Facts
Patent No.
US 12678272
App. No.
18/668,824
Granted
Jul 14, 2026
Kind
B2
Abstract

A method of reducing counterfeit medicaments or reducing medicament abuse is provided, the method comprising making an oral appliance for delivering a medicament to teeth and/or soft tissue areas inside an oral cavity, the oral appliance comprising an interior surface having a medicament disposed in or on at least a portion of and/or all of the interior surface of the oral appliance, the interior surface being formed to fit contours of at least the portion of the teeth and/or soft tissue areas inside the oral cavity and being configured for holding the medicament in contact with at least the portion of the teeth and/or soft tissue areas inside the oral cavity to deliver the medicament thereto. In some embodiments, the oral appliance is used in a blockchain system.

Claims (13)

1 . A method of reducing counterfeit medicaments, the method comprising making an oral appliance for delivering a medicament to at least a portion of teeth and/or soft tissue areas inside an oral cavity, the oral appliance comprising an interior surface having a medicament disposed in or on at least a portion of and/or all of the interior surface of the oral appliance, the interior surface being formed to fit contours of at least the portion of the teeth and/or soft tissue areas inside the oral cavity and being configured for holding the medicament in contact with at least the portion of the teeth and/or soft tissue areas inside the oral cavity to deliver the medicament thereto, wherein the oral appliance comprises a unique identifier disposed on a surface of the oral appliance.

2 . The method of claim 1 , wherein the oral appliance is monolithic and the interior surface custom fit to the contours of the teeth and/or soft tissue areas inside the oral cavity of a patient in need of treatment.

3 . The method of claim 1 , wherein the medicament is disposed at discrete regions of the oral appliance and the unique identifier is also disposed at those discrete regions or adjacent to those discrete regions of the oral appliance to authenticate the strength, dose and type of medicament.

4 . The method of claim 1 , wherein the oral appliance is made using a digital scan of the oral cavity from a database of stored digital scans from individual patients.

5 . The method of claim 1 , wherein the unique identifier is part of a blockchain system generated by a database that represents unique information, data or characteristics about the oral appliance and the medicament.

6 . A method of reducing medicament abuse, the method comprising making an oral appliance for delivering the medicament to at least a portion of teeth and/or soft tissue areas inside an oral cavity, the oral appliance comprising an interior surface having a medicament disposed in or on at least a portion of and/or all of the interior surface of the oral appliance, the interior surface being formed to fit contours of at least the portion of the teeth and/or soft tissue areas inside the oral cavity and being configured for holding the medicament in contact with at least the portion of the teeth and/or soft tissue areas inside the oral cavity to deliver the medicament thereto, wherein the oral appliance comprises a unique identifier disposed on a surface of the oral appliance.

7 . The method of claim 6 , wherein the oral appliance is monolithic and the interior surface custom fit to the contours of the teeth and/or soft tissue areas inside the oral cavity of a patient in need of treatment.

8 . The method of claim 7 , wherein the medicament is disposed at discrete regions of the oral appliance and the unique identifier is also disposed at those discrete regions or adjacent to those discrete regions of the oral appliance to authenticate the strength, dose and type of medicament.

9 . The method of claim 7 , wherein the oral appliance is made using a digital scan of the oral cavity from a database of stored digital scans from individual patients.

10 . The method of claim 7 , wherein the unique identifier comprises a blockchain structure generated by a database that represents unique information, data or characteristics about the oral appliance and the medicament.

11 . A method of making an oral appliance for delivering a medicament to an oral cavity, the method comprising forming a non-porous material into a portion of the oral appliance; applying a porous material to one or more discrete regions of the portion of the oral appliance to make the one or more discrete regions of the oral appliance porous thereby forming the oral appliance; and imprinting information on a surface of the oral appliance, wherein the oral appliance comprises a unique identifier disposed on a surface of the oral appliance.

12 . The method of making the oral appliance of claim 11 , wherein (i) the information is a blockchain structure generated by a database; (ii) the information is 3D printed, lasered, stamped, or a combination thereof on the device; or (iii) the information is adjacent to the one or more discrete regions that contain medicament.

13 . The method of making the oral appliance of claim 12 , wherein (i) the printed information is encrypted; or (ii) the printed information is a blockchain structure that represents unique information, data or characteristics about the oral appliance and the medicament.