IP Library Granted Patent US 12678379
Granted Patent B2
US 12678379 · App. 17/789,264 · Granted Jul 14, 2026

Paste-like composition for dental use, and method for producing the same

Inventors: Mariko Kawana (Niigata, JP); Nobusuke Kashiki (Aichi, JP)
Assignee: KURARAY NORITAKE DENTAL INC.
A61K6/71A61K6/15A61K6/30
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Quick Facts
Patent No.
US 12678379
App. No.
17/789,264
Granted
Jul 14, 2026
Kind
B2
Abstract

The present invention provides a paste-like composition for dental use that shows stable consistency and runniness and little stringiness immediately after production and even after long storage. The present invention relates to a paste-like composition for dental use, comprising a polymerizable monomer (A) and a filler (B), the filler (B) comprising a particulate filler (B-1) having an average primary particle diameter of 0.001 to 0.2 μm, and a filler (B-2) having an average primary particle diameter of more than 0.2 μm and 30 μm or less, the paste-like composition having a consistency of 15 to 40 mm, the particulate filler (B-1) having an average secondary particle diameter of 20 μm or less.

Claims (20)

1 . A method for producing a paste-like composition for dental use that comprises a polymerizable monomer (A) and a filler (B), and in which the filler (B) comprises a particulate filler (B-1) having an average primary particle diameter of 0.001 to 0.2 μm, comprising:

mixing the polymerizable monomer (A) and the particulate filler (B-1) having an average primary particle diameter of 0.001 to 0.2 μm to obtain an intermediate paste; and

additionally mixing the polymerizable monomer (A) with the intermediate paste to obtain a final paste as the paste-like composition for dental use,

the particulate filler (B-1) being mixed in an amount of 30 to 150 parts by mass relative to total 100 parts by mass of a total amount of polymerizable monomer (A) in obtaining the intermediate paste, wherein:

polymerizable monomer (A) is at least one of a polymerizable monomer having a phosphoric acid group, a polymerizable monomer having a sulfonic acid group, a polymerizable monomer having a carboxylic acid group, a hydrophobic monofunctional polymerizable monomer having no acidic group, an aromatic bifunctional polymerizable monomer having no acidic group, an aliphatic bifunctional polymerizable monomer having no acidic group, and a tri- or higher-functional polymerizable monomer having no acidic group;

the particulate filler (B-1) is not added to the intermediate paste during said additionally mixing to obtain the final paste;

the final paste has a consistency of 15 to 40 mm;

the particulate filler (B-1) contained in the final paste has an average secondary particle diameter of 20 μm or less;

the intermediate paste has a consistency of 5 to 20 mm; and

a content of polymerizable monomer (A) is 5 to 60 parts by mass relative to a total 100 parts by mass of the paste-like composition for dental use.

2 . The method for producing a paste-like composition for dental use according to claim 1 , wherein the particulate filler (B-1) contained in the final paste has an average secondary particle diameter of 10 μm or less.

3 . The method for producing a paste-like composition for dental use according to claim 2 , wherein the intermediate paste has a consistency of 10 to 16 mm.

4 . The method for producing a paste-like composition for dental use according to claim 1 , wherein the particulate filler (B-1) contained in the intermediate paste has an average secondary particle diameter of 100 μm or less.

5 . The method for producing a paste-like composition for dental use according to claim 1 , wherein the paste-like composition for dental use further comprises a filler (B-2) having an average primary particle diameter of more than 0.2 μm and 30 μm or less.

6 . The method for producing a paste-like composition for dental use according to claim 5 , wherein the filler (B-2) is mixed when obtaining the intermediate paste.

7 . The method for producing a paste-like composition for dental use according to claim 5 , wherein the filler (B-2) is mixed when obtaining the final paste.

8 . The method for producing a paste-like composition for dental use according to claim 1 , wherein the particulate filler (B-1) contained in the final paste has an average secondary particle diameter of 5 μm or less.

9 . The method for producing a paste-like composition for dental use according to claim 8 , wherein the paste-like composition for dental use further comprises a filler (B-2) having an average primary particle diameter of more than 0.2 μm and 30 μm or less.

10 . The method for producing a paste-like composition for dental use according to claim 9 , wherein the filler (B-2) is mixed when obtaining the intermediate paste.

11 . The method for producing a paste-like composition for dental use according to claim 9 , wherein the filler (B-2) is mixed when obtaining the final paste.