IP Library Granted Patent US 12678545
Granted Patent B2
US 12678545 · App. 17/912,963 · Granted Jul 14, 2026

Dialysis system and dialysis system operation method

Inventors: Toshihiko Mizuno (Hamamatsu, JP); Takashi Watanabe (Hamamatsu, JP)
Assignee: HAMAMATSU PHOTONICS K.K.
A61M1/14A61M1/36
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Quick Facts
Patent No.
US 12678545
App. No.
17/912,963
Granted
Jul 14, 2026
Kind
B2
Abstract

A dialysis system includes a dialysis apparatus, a measurement apparatus, and a control apparatus. The dialysis apparatus performs hemodialysis on a dialysis subject. The measurement apparatus measures a cerebral regional oxygen saturation of the dialysis subject. The control apparatus adjusts a hemodialysis operating condition by the dialysis apparatus so as to suppress decrease in the cerebral rSO2 based on the cerebral rSO2 of the dialysis subject measured by the measurement apparatus during operation of the hemodialysis by the dialysis apparatus.

Claims (16)

1 . A dialysis system comprising:

a dialysis apparatus configured to perform hemodialysis on a dialysis subject;

a measurement apparatus configured to measure a regional oxygen saturation of the dialysis subject;

a probe connected to the measurement apparatus, provided on a forehead of the dialysis subject, and including an emission unit and a plurality of detection units which are spaced apart from each other; and

a control apparatus configured to adjust a hemodialysis operating condition by the dialysis apparatus so as to suppress decrease in the regional oxygen saturation based on the regional oxygen saturation measured by the measurement apparatus during operation of the hemodialysis by the dialysis apparatus, wherein

the measurement apparatus is configured to apply light from the emission unit to the forehead of the dialysis subject, and detect the light after being scattered and absorbed in a brain of the dialysis subject by each of the plurality of detection units,

the measurement apparatus is configured to measure, as the regional oxygen saturation, a cerebral regional oxygen saturation in each of a plurality of portions of the forehead of the dialysis subject corresponding to the plurality of detection units of the probe, and

the measurement apparatus is configured to, when any measured value out of measured values of the cerebral regional oxygen saturation in the plurality of portions is determined to be abnormal, exclude the abnormal measured value and use another measured value.

2 . The dialysis system according to claim 1 , wherein the control apparatus is configured to adjust the hemodialysis operating condition by the dialysis apparatus so as to suppress decrease in the regional oxygen saturation when a decrease ratio of the regional oxygen saturation measured by the measurement apparatus during the operation of the hemodialysis by the dialysis apparatus becomes larger than a threshold value with respect to the regional oxygen saturation measured by the measurement apparatus before the operation of the hemodialysis by the dialysis apparatus.

3 . The dialysis system according to claim 1 , wherein the control apparatus is configured to adjust the hemodialysis operating condition by the dialysis apparatus so as to suppress decrease in the regional oxygen saturation when a decreasing rate of the regional oxygen saturation measured by the measurement apparatus during the operation of the hemodialysis by the dialysis apparatus becomes larger than a threshold value.

4 . The dialysis system according to claim 1 , wherein the control apparatus is configured to adjust a blood flow rate in the dialysis apparatus so as to suppress decrease in the regional oxygen saturation.

5 . The dialysis system according to claim 1 , wherein the control apparatus is configured to adjust a dialysis fluid flow rate in the dialysis apparatus so as to suppress decrease in the regional oxygen saturation.

6 . The dialysis system according to claim 1 , wherein the control apparatus is configured to adjust a temperature of a dialysis fluid in the dialysis apparatus so as to suppress decrease in the regional oxygen saturation.

7 . The dialysis system according to claim 1 , wherein the control apparatus is configured to adjust a water removal amount in the dialysis apparatus so as to suppress decrease in the regional oxygen saturation.

8 . The dialysis system according to claim 1 , wherein the control apparatus is configured to adjust an amount or timing of fluid replacement in the dialysis apparatus so as to suppress decrease in the regional oxygen saturation.

9 . The dialysis system according to claim 1 , wherein the control apparatus is configured to adjust a height of a placing stage configured to place a head or a leg of the dialysis subject in the dialysis apparatus so as to suppress decrease in the regional oxygen saturation.