Method for estimating inhale dose of a person
A method for estimating an inhale dose when a drug is delivered to a person using an inhaler is disclosed. A predicted inhale dose (PID) of the drug is estimated based on at least one first-type parameter and at least one second-type parameter. The first-type parameter is related to a breath pattern of the person, and the second-type parameter is related to the inhaler.
1 . A method for estimating an inhale dose when a drug is delivered to a person using an inhaler, the method comprising:
obtaining, by an analyzer from a breathing module, a first-type parameter related to a breath pattern of the person when the drug is delivered to the person through the inhaler;
obtaining, by the analyzer, a second-type parameter related to the inhaler;
estimating, by the analyzer, a predicted inhale dose of the drug after the drug is delivered to the person through the inhaler for a period of time, based on the first-type parameter and the second-type parameter; and
showing the predicted inhale dose upon the predicted inhale dose being estimated by the analyzer, wherein the predicted inhale dose is estimated according to the following formula:
PID =( TD−RC )*( I /( E+I ))− DP+RP
wherein TD is a total drug amount in an aerosol generator of the inhaler and obtained from the aerosol generator, RC is a drug residue amount in the aerosol generator and obtained from the aerosol generator, I is an inspiratory time of the person and derived from the breath pattern, E is an expiratory time of the person and derived from the breath pattern, DP is a drug deposit in an inlet path of the inhaler and included in the second-type parameter, and RP is a drug reserve in an outlet path of the inhaler and included in the second-type parameter.
2 . The method of claim 1 , wherein the first-type parameter includes an inspiratory time of the person or an expiratory time of the person.
3 . The method of claim 1 , wherein the first-type parameter is obtained by measuring the breath pattern of the person.
4 . The method of claim 1 , wherein the second-type parameter is obtained from a look-up table according to a type of the inhaler.
5 . An apparatus for estimating an inhale dose when a drug is delivered to a person using an inhaler, the apparatus comprising:
a processor; and
a memory storing instructions thereon, wherein the processor is capable of executing the instructions to perform the steps of:
obtaining, from a breathing module, a first-type parameter related to a breath pattern of the person when the drug is delivered to the person through the inhaler;
obtaining a second-type parameter related to the inhaler;
estimating a predicted inhale dose of the drug after the drug is delivered to the person through the inhaler for a period of time, based on the first-type parameter and the second-type parameter; and
showing the predicted inhale dose upon the predicted inhale dose being estimated by the analyzer, wherein the predicted inhale dose is estimated according to the following formula:
PID =( TD−RC )*( I /( E+I ))− DP+RP
wherein TD is a total drug amount in an aerosol generator of the inhaler and is obtained from the aerosol generator, RC is a drug residue amount in the aerosol generator and is obtained from the aerosol generator, I is an inspiratory time of the person and is derived from the breath pattern, E is an expiratory time of the person and is derived from the breath pattern, DP is a drug deposit in an inlet path of the inhaler and is included in the second-type parameter, and RP is a drug reserve in an outlet path of the inhaler and is included in the second-type parameter.
6 . The apparatus of claim 5 , wherein the first-type parameter includes an inspiratory time of the person or an expiratory time of the person.
7 . The apparatus of claim 5 , wherein the first-type parameter is obtained by measuring the breath pattern of the person.
8 . The apparatus of claim 5 , wherein the second-type parameter is obtained from a look-up table according to a type of the inhaler.
9 . A non-transitory storage medium with instructions stored thereon for estimating an inhale dose when a drug is delivered to a person using an inhaler, wherein a processor is capable of executing the instructions to perform the following steps:
obtaining, by an analyzer from a breathing module, a first-type parameter related to a breath pattern of the person when the drug is delivered to the person through the inhaler;
obtaining, by the analyzer, a second-type parameter related to the inhaler;
estimating, by the analyzer, a predicted inhale dose of the drug after the drug is delivered to the person through the inhaler for a period of time, based on the first-type parameter and the second-type parameter; and
showing the predicted inhale dose upon the predicted inhale dose being estimated by the analyzer, wherein the predicted inhale dose is estimated according to the following formula:
PID =( TD−RC )*( I /( E+I ))− DP+RP
wherein TD is a total drug amount in an aerosol generator of the inhaler and is obtained from the aerosol generator, RC is a drug residue amount in the aerosol generator and is obtained from the aerosol generator, I is an inspiratory time of the person and is derived from the breath pattern, E is an expiratory time of the person and is derived from the breath pattern, DP is a drug deposit in an inlet path of the inhaler and is included in the second-type parameter, and RP is a drug reserve in an outlet path of the inhaler and is included in the second-type parameter.
10 . The non-transitory storage medium of claim 9 , wherein the first-type parameter includes an inspiratory time of the person or an expiratory time of the person.
11 . The non-transitory storage medium of claim 9 , wherein the first-type parameter is obtained by measuring the breath pattern of the person.
12 . The non-transitory storage medium of claim 9 , wherein the second- type parameter is obtained from a look-up table according to a type of the inhaler.
13 . A method for delivering a drug to a person using an inhaler, comprising:
inputting, to an analyzer, information related to a type of the inhaler;
measuring, by a breathing module, a breath pattern of the person; and
determining an inhale dose according to a predicted inhale dose of the drug shown by the analyzer after the drug is delivered to the person through the inhaler for a period of time, wherein the predicted inhale dose of the drug is estimated by the analyzer based on a first-type parameter related to the breath pattern of the person and a second-type parameter related to the inhaler, wherein the predicted inhale dose is estimated according to the following formula:
PID =( TD−RC )*( I /( E+I ))− DP+RP
wherein TD is a total drug amount in an aerosol generator of the inhaler and is obtained from the aerosol generator, RC is a drug residue amount in the aerosol generator and is obtained from the aerosol generator, I is an inspiratory time of the person and is derived from the breath pattern, E is an expiratory time of the person and is derived from the breath pattern, DP is a drug deposit in an inlet path of the inhaler and is included in the second-type parameter, and RP is a drug reserve in an outlet path of the inhaler and is included in the second- type parameter.
14 . The method of claim 13 , wherein the first-type parameter includes an inspiratory time of the person or an expiratory time of the person.
15 . The method of claim 13 , wherein the second-type parameter is obtained from a look-up table according to the type of the inhaler.