IP Library Granted Patent US 12678626
Granted Patent B2
US 12678626 · App. 18/546,917 · Granted Jul 14, 2026

Determining electrode combinations for sensing

Inventors: David A. Dinsmoor (North Oaks, MN); Juan G. Hincapie (Maple Grove, MN); Leonid M. Litvak (Bet Shemesh, IL)
Assignee: Medtronic, Inc.
A61N1/36139
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Quick Facts
Patent No.
US 12678626
App. No.
18/546,917
Granted
Jul 14, 2026
Kind
B2
Abstract

Systems, devices, and techniques for analyzing evoked compound action potentials (ECAP)signals to evaluate and select an electrode combination. A method includes controlling, by processing circuitry, deliver of a plurality of stimulation pulses via at least one stimulation electrode combination, receiving, by the processing circuitry, evoked compound action potential (ECAP) signal information representing different ECAP signals evoked from respective stimulation pulses of the plurality of stimulation pulses and obtained from respective different sensing electrode combinations, selecting by the processing circuitry and based on the ECAP signal information, one electrode combination from the different sensing electrode combinations.

Claims (36)

1 . A system comprising:

processing circuitry configured to:

control delivery of a plurality of stimulation pulses via at least one stimulation electrode combination;

receive evoked compound action potential (ECAP) signal information representing different ECAP signals evoked from respective stimulation pulses of the plurality of stimulation pulses and obtained from respective different sensing electrode combinations; and

select, based on the ECAP signal information, one sensing electrode combination from the different sensing electrode combinations.

2 . The system of claim 1 , wherein the ECAP signal information includes at least one of a stimulation artifact or an electrophysiologic component.

3 . The system of claim 2 , wherein the processing circuitry is configured to select the one sensing electrode combination by at least determining that at least one of the stimulation artifact or the electrophysiologic component of the ECAP signal sensed obtained by the one sensing electrode combination satisfies a threshold.

4 . The system of claim 2 , wherein the processing circuitry is configured to select the one sensing electrode combination by at least:

comparing the electrophysiologic component from the respective ECAP signals from each sensing electrode combination of the different sensing electrode combinations; and

determining the one sensing electrode combination as the sensing electrode combination of the different sensing electrode combinations having the largest electrophysiologic component.

5 . The system of claim 1 , wherein the ECAP signal information comprises ECAP signals sensed by sensing circuitry and elicited by the plurality of stimulation pulses to the different sensing electrode combinations, and wherein the processing circuitry is further configured to determine, based on the ECAP signal information, ECAP characteristic values for the ECAP signals elicited by the plurality of stimulation pulses.

6 . The system of claim 5 , wherein the processing circuitry is configured to select the one sensing electrode combination by at least selecting, based on the ECAP characteristic values, the one sensing electrode combination from the different sensing electrode combinations.

7 . The system of claim 5 , wherein the processing circuitry is configured to select the one sensing electrode combination by at least selecting the one sensing electrode combination in response to the ECAP characteristic value satisfying a threshold.

8 . The system of claim 1 , wherein the plurality electrode combinations comprises different sensing electrode combinations from an electrode array having more than eight electrodes.

9 . The system of claim 1 , wherein the at least one stimulation electrode combination comprises at least one of a bipolar, a tripolar, or a multipolar electrode configuration.

10 . The system of claim 1 , wherein the at least one stimulation electrode combination is different from the different sensing electrode combinations.

11 . The system of claim 1 , wherein the processing circuitry is configured to:

compare amplitudes of stimulation artifacts from the respective different ECAP signals from each sensing electrode combination of the different sensing electrode combinations; and

determine, based on the comparison, the one sensing electrode combination from the different sensing electrode combinations having a lowest amplitude of the stimulation artifacts, wherein the processing circuitry is configured to select the one sensing electrode combination by at least selecting the one sensing electrode combination having the lowest amplitude of the stimulation artifact.

12 . The system of claim 1 , further comprising an implantable medical device comprising the processing circuitry and sensing circuitry, the sensing circuitry configured to sense subsequent ECAP signals via the one sensing electrode combination.

13 . The system of claim 1 , further comprising an external programmer comprising the processing circuitry, the external programmer configured to communicate with an implantable medical device configured to deliver the plurality of stimulation pulses.

14 . A method comprising:

controlling, by processing circuitry, delivery of a plurality of stimulation pulses via at least one stimulation electrode combination;

receiving, by the processing circuitry, evoked compound action potential (ECAP) signal information representing different ECAP signals evoked from respective stimulation pulses of the plurality of stimulation pulses and obtained from respective different sensing electrode combinations; and

selecting, by the processing circuitry and based on the ECAP signal information, one sensing electrode combination from the different sensing electrode combinations.

15 . The method of claim 14 , wherein the ECAP signal information includes at least one of a stimulation artifact or an electrophysiologic component.

16 . The method of claim 15 , wherein selecting the one sensing electrode combination comprises determining that at least one of the stimulation artifact or the electrophysiologic component of the ECAP signal sensed obtained by the one sensing electrode combination satisfies a threshold.

17 . The method of claim 15 , wherein selecting the one sensing electrode combination comprises: comparing the electrophysiologic component from the respective ECAP signals from each sensing electrode combination of the different sensing electrode combinations; and determining the one sensing electrode combination as the sensing electrode combination of the different sensing electrode combinations having the largest electrophysiologic component.

18 . The method of claim 14 , wherein the ECAP signal information comprises ECAP signals sensed by sensing circuitry and elicited by the plurality of stimulation pulses to the different sensing electrode combinations, further comprising determining, by the processing circuitry and based on the ECAP signal information, ECAP characteristic values for the ECAP signals elicited by the plurality of stimulation pulses.

19 . The method of claim 14 , further comprising:

comparing amplitudes of stimulation artifacts from the respective different ECAP signals from each sensing electrode combination of the different sensing electrode combinations; and

determining, based on the comparison, one sensing electrode combination from the different sensing electrode combinations having a lowest amplitude of the stimulation artifacts, wherein selecting the one sensing electrode combination comprises selecting the one sensing electrode combination having the lowest amplitude of the stimulation artifact.

20 . A non-transitory computer-readable storage medium comprising instructions that, when executed, cause processing circuitry to:

control delivery of a plurality of stimulation pulses via at least one stimulation electrode combination;

receive evoked compound action potential (ECAP) signal information representing different ECAP signals evoked from respective stimulation pulses of the plurality of stimulation pulses and obtained from respective different sensing electrode combinations; and

select, based on the ECAP signal information, one sensing electrode combination from the different sensing electrode combinations.