Conversion of nitrogen dioxide (NO
Various systems, devices, NO 2 absorbents, NO 2 scavengers and NO 2 recuperator for generating nitric oxide are disclosed herein. According to one embodiment, an apparatus for converting nitrogen dioxide to nitric oxide can include a receptacle including an inlet, an outlet, a surface-active material coated with an aqueous solution of ascorbic acid and an absorbent wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the surface-active material and the absorbent such that nitrogen dioxide in the gas flow is converted to nitric oxide.
1 . A system for delivering nitric oxide to a patient, comprising:
an apparatus;
a gas source comprising nitrogen dioxide that is delivered to the apparatus, wherein the apparatus converts the nitrogen dioxide to a gas comprising nitric oxide that is delivered to the patient; and
at least one safety device comprising a filter, wherein the filter is a particle and/or bacteria filter having a disk or tubular shape, wherein the filter is positioned in a flow path between the apparatus and the patient, and wherein
the at least one safety device is further configured to reduce an amount of the nitrogen dioxide in the gas comprising nitric oxide before it is delivered to the patient in an amount below 0.1 ppm.
2 . The system of claim 1 , wherein the at least one safety device comprises a scavenger material.
3 . The system of claim 2 , wherein the scavenger comprises proline or diphenylamine.
4 . The system of claim 1 , wherein the at least one safety device is a recuperator that is operated at atmospheric pressure.
5 . The system of claim 4 , wherein the recuperator comprises a scavenger.
6 . The system of claim 4 , wherein the recuperator exhibits a pressure drop of less than 3 cm of water when a gas flow from the gas source is at 60 liter per minute.
7 . The system of claim 4 , wherein the recuperator has an oxygen concentration in a range of 21% to 100%.
8 . The system of claim 4 , wherein the recuperator is positioned immediately adjacent to the patient.
9 . The system of claim 4 , further comprising a sample probe positioned at an exist portion of the recuperator and fluidically connected to a gas analyzer.
10 . The system of claim 2 , wherein the filter prevents dust from the scavenger material from being delivered to the patient.
11 . The system of claim 1 , wherein the apparatus further comprises a surface active material.
12 . The system of claim 11 , wherein the surface active material is a silica gel.
13 . The system of claim 12 , wherein the filter prevents dust from the silica gel from being delivered to the patient.