IP Library Granted Patent US 12680129
Granted Patent B2
US 12680129 · App. 17/640,410 · Granted Jul 14, 2026

Sample preservation solution, and analysis device and analysis method using the same

Inventor: Tadao Kunihiro (Shizuoka, JP)
Assignee: TECHNOSURUGA LABORATORY CO., LTD.
C12Q1/686A01N1/12C12Q1/02
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Quick Facts
Patent No.
US 12680129
App. No.
17/640,410
Granted
Jul 14, 2026
Kind
B2
Abstract

The present invention provides means with which bile acids, phenols, indoles and organic acids contained in a sample can be stably preserved without cryopreservation of the sample. A sample preservation solution of the present invention is a sample preservation solution used for analyzing at least one component selected from the group consisting of bile acids, phenols, indoles and organic acids contained in a biological or environmental sample, containing at least the following (A) and (B): (A) condensed phosphate or polyoxyethylene sorbitan alkylate; and (B) guanidinium thiocyanate, Tris-HCl (pH 7 to 9), and EDTA.

Claims (9)

1 . A sample preservation solution used for analyzing at least one component selected from the group consisting of bile acids, phenols, indoles and organic acids contained in a biological or environmental sample, comprising both (A) and (B):

(A) condensed phosphate; and

(B) guanidinium thiocyanate, Tris-HCl (pH 7 to 9), and EDTA.

2 . The sample preservation solution according to claim 1 , wherein the condensed phosphate is 5 mM to 150 mM sodium pyrophosphate.

3 . The sample preservation solution according to claim 1 ,

wherein a concentration of the guanidinium thiocyanate is 0.1 M to 5 M,

a concentration of the Tris-HCl (pH 7 to 9) is 40 mM to 150 mM, and

a concentration of the EDTA is 1 mM to 50 mM.

4 . The sample preservation solution according to claim 1 , wherein the sample is feces.