IP Library Granted Patent US 12685453
Granted Patent B2
US 12685453 · App. 18/266,354 · Granted Jul 21, 2026

System and method for monitoring blood perfusion

Inventors: Marco Lai (Eindhoven, NL); Claudio Dicorato (Milan, IT); Frank Verbakel (Helmond, NL); Gerhardus Wilhelmus Lucassen (Eindhoven, NL); Nico Maris Adriaan De Wild (Eindhoven, NL); Marc Godfriedus Marie Notten (Elsloo, NL)
Assignee: Koninklijke Philips N.V.
A61B5/0261A61B5/02416
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Quick Facts
Patent No.
US 12685453
App. No.
18/266,354
Granted
Jul 21, 2026
Kind
B2
Abstract

An apparatus (and method) is for monitoring blood perfusion. A plurality of photoplethysmography, PPG, signals are acquired indicative of light detected in a region of interest of tissue at a plurality of respective locations within the region. The PPG signals are processed to determine an amplitude and preferably also a phase of each of the plurality of PPG signals, and a blood perfusion level is determined at the region of interest based on the amplitudes and preferably also the phases of the PPG signals.

Claims (26)

1 . An apparatus for monitoring blood perfusion, the apparatus comprising a processor configured to:

acquire, from at least one sensor, a plurality of photoplethysmography, PPG, signals indicative of light detected in a region of interest of tissue at a plurality of respective locations within the region;

process the acquired plurality of PPG signals to determine an amplitude and a phase of each of the plurality of PPG signals, wherein the phase indicates a relative pulse arrival time to the respective locations; and

determine a blood perfusion level at the region of interest based on a ratio of a first value indicating the amplitudes of the PPG signals within the region of interest and a second value indicating a measure of distribution of phases of the PPG signals across the region of interest.

2 . The apparatus of claim 1 , wherein the processor is configured to:

determine the first value from an average of the determined amplitude value for the locations within the region of interest; and

determine the second value from a distribution of the phase values for the locations within the region of interest.

3 . The apparatus of claim 2 , wherein the first value is a median or mean of the amplitudes for the locations.

4 . The apparatus of claim 2 , wherein the second value is an interquartile range or standard deviation of the phase for the locations.

5 . The apparatus of claim 1 , wherein the processor is configured to determine the blood perfusion at the region of interest as a value relative to the blood perfusion for the region of interest at a previous time.

6 . The apparatus of claim 1 , wherein the processor is further configured to:

acquire from at least one further sensor a plurality of photoplethysmography, PPG, signals, indicative of light detected in a reference region and to determine a blood perfusion level for the reference region; and

determine the blood perfusion at the region of interest as a value relative to the blood perfusion for the reference region.

7 . The apparatus of claim 1 , wherein the at least one sensor is a non-contact PPG sensor.

8 . A method for monitoring blood perfusion, comprising:

acquiring, from at least one sensor, a plurality of photoplethysmography, PPG, signals indicative of light detected in a region of interest of tissue at a plurality of respective locations within the region;

processing the acquired plurality of PPG signals to determine an amplitude and a phase of each of the plurality of PPG signals, wherein the phase indicates a relative pulse arrival time to the respective locations; and

determining a blood perfusion level at the region of interest based on a ratio of a first value indicating the amplitudes of the PPG signals within the region of interest and a second value indicating a measure of distribution of phases of the PPG signals across the region of interest.

9 . The method of claim 8 , comprising:

determining the first value relating to an average of the determined amplitude value for the locations within the region of interest; and

determining the second value relating to a distribution of the phase values for the locations within the region of interest.

10 . The method of claim 9 , wherein the first value is a median or men of the amplitudes for the locations and the second value is an interquartile range or standard deviation of the phase for the locations.

11 . The method of claim 9 , comprising:

determining the blood perfusion at the region of interest as a value relative to the blood perfusion for the region of interest at a previous time; or

determining the blood perfusion at the region of interest as a value relative to the blood perfusion for a reference region.

12 . A computer program comprising computer program code means which is adapted, when said program is run on a computer of an apparatus for monitoring blood perfusion which includes a PPG sensor, to implement the method of claim 9 .