IP Library Granted Patent US 12685697
Granted Patent B2
US 12685697 · App. 18/610,728 · Granted Jul 21, 2026

DMS (derma membrane structure) in foam creams

Inventor: Thomas Neubourg (Werne, DE)
Assignee: nsc Pharma GmbH & Co.
A61K8/046A61K8/0295A61K8/36A61K8/375A61K8/553A61Q17/04A61Q19/005A61Q19/007A61Q19/10A61K2800/33
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Quick Facts
Patent No.
US 12685697
App. No.
18/610,728
Granted
Jul 21, 2026
Kind
B2
Abstract

The invention relates to a foam formulation comprising an emulsion, comprising an oil phase and a water phase, the oil phase comprising at least one membrane-forming substance forming a lamellar membrane in the foam formulation.

Claims (10)

1 . A foam formulation comprising an oil-in-water emulsion which comprises an oil phase and a water phase, wherein the oil phase comprises membrane-forming substances that form a lamellar membrane within the emulsion, said membrane-forming substances comprising at least one phospholipid and at least one lipid selected from the group consisting of a triglyceride and a liquid wax ester, wherein the formulation contains less than 1.5% by weight of amphiphilic, micelle-forming compounds having a molecular weight of less than 5000, and wherein said lamellar membrane is characterized by the presence of Maltese crosses when viewed under a polarization microscope.

2 . The foam formulation of claim 1 , wherein the at least one phospholipid is hydrogenated lecithin and the triglyceride is a caprylic/capric acid triglyceride.

3 . The foam formulation of claim 1 , wherein the at least one phospholipid comprises a mixture of lecithin and hydrogenated lecithin.

4 . The foam formulation of claim 1 , wherein the at least one lipid is a liquid wax ester comprising isopropyl myristate.

5 . The foam formulation of claim 1 , wherein the weight ratio of the at least one phospholipid to the at least one lipid is from 1:5 to 1:1.

6 . The foam formulation of claim 1 , further comprising at least one thickening agent selected from the group consisting of hydroxypropylmethyl cellulose and xanthan gum.

7 . The foam formulation of claim 1 , further comprising a stabilizer comprising pentylene glycol.

8 . The foam formulation of claim 1 , further comprising one or more components selected from the group consisting of shea butter, squalane, and ceramide 3.

9 . The foam formulation of claim 1 , wherein the membrane-forming substances have an HLB value between 9 and 11.

10 . The foam formulation of claim 1 , wherein the formulation is a foam cream.