Skin care composition

Inventors: Daniel Richter (Niederfrohna, DE); Jennifer Huepeden (Hamburg, DE); Joern Hendrik Reuter (Henstedt-Ulzburg, DE); Heike Foelster (Hamburg, DE); Bernhard Felten (Pinneberg, DE); Jane Djamil (Hamburg, DE); Peter Steidle (Hamburg, DE); Petra Schoendienst (Tornesch, DE); Tina Hamann (Brodersby-Goltoft, DE); Stefan Gallinat (Wedel, DE); Willy Verheyen (Vosselaar, BE); João Pedro Quintão Reis Pereira De Lima (Antwerp, BE); Bernhard Felix Paetzold (Berchem, BE)

Assignees: BEIERSDORF AG; S-BIOMEDIC

A61K8/99 A61K9/19 A61K35/74 A61Q19/00 A61K2800/48 A61K2800/522 A61K2800/524 A61K2800/84

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Quick Facts

Patent No.: US 12685708
App. No.: 17/754,426
Granted: Jul 21, 2026
Kind: B2

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USPTO Patent Center↗ Full Patent PDF↗

Abstract

The present invention generally relates to the field of skin care. More particularly, the invention relates to a cosmetic or therapeutic skin care composition comprising live bacteria of at least one Cutibacterium acnes ( C. acnes ) strain in combination with an excipient that specifically supports their viability during storage and/or their ability to replicate after application to the skin. Preferably, the cosmetic or therapeutic skin care composition comprises bacteria of at least one C. acnes strain selected from the group consisting of D1, A5, C1, C3, H1, H2, H3, K1, K2, K4, K6, K8, K9, L1, and F4. The invention also provides a method for treating or preventing acne by applying the skin care composition of the invention to a skin area in need of treatment. The invention also relates to the use of a skin care composition of the invention for treating or preventing acne.

Claims (28)

1 . A skin care composition, wherein the composition is suitable for topical application to skin and comprises:

(a) lyophilized and/or spray dried live bacteria of at least one strain of Cutibacterium acnes ( C. acnes ); and

(b) one or more of:

(b1) dicaprylyl carbonate and/or ethylhexyl cocoate as emollient;

(b2) Chondrus crispus extract and/or hydroxypropyl starch as thickener;

(b3) distarch phosphate and/or tapioca starch as filler;

(b4) tocopherol and/or tocopheryl acetate as antioxidant;

and

(b6) PEG-40 hydrogenated castor oil as solubilizer.

2 . The skin care composition of claim 1 , wherein the composition comprises at least (b1).

3 . The skin care composition of claim 1 , wherein the composition comprises at least (b2).

4 . The skin care composition of claim 1 , wherein the composition comprises at least (b3).

5 . The skin care composition of claim 1 , wherein the composition comprises at least (b4).

6 . The skin care composition of claim 1 , wherein the composition comprises at least (b6).

7 . The skin care composition of claim 1 , wherein the composition comprises at least two of (b1) to (b4) and (b6).

8 . The skin care composition of claim 1 , wherein the composition comprises at least three of (b1) to (b4) and (b6).

9 . The skin care composition of claim 1 , wherein the composition comprises at least four of (b1) to (b4) and (b6).

10 . The skin care composition of claim 1 , wherein the composition comprises all of (b1) to (b4) and (b6).

11 . The skin care composition of claim 1 , wherein the composition further comprises citric acid/citrate buffer as a pH adjuster.

12 . The skin care composition of claim 1 , wherein the at least one strain of C. acnes comprises at least one of single-locus sequence typing (SLST) type strains D1, A5, C1, C3, H1, H2, H3, K1, K2, K4, K6, K8, K9, L1, F4.

13 . The skin care composition of claim 12 , wherein the at least one strain of C. acnes comprises at least one SLST type strain C3 and/or at least one SLST type strain K8.

14 . The skin care composition of claim 13 , wherein the at least one strain of C. acnes further comprises at least one SLST type strain A5 and/or at least one SLST type strain F4.

15 . The skin care composition of claim 1 , wherein a concentration of each type of C. acnes strain present in the composition is at least 0.5% (w/v) of the skin care composition.

16 . The skin care composition of claim 1 , wherein each type of the C. acnes strain in the composition is present in an amount of from 10 4 to 10 11 CFU/ml.

17 . The skin care composition of claim 1 , wherein the composition is present in the form of at least one of a gel, a cream, an ointment or a lotion.

18 . The skin care composition of claim 1 , wherein the composition is capable of treating or preventing one or more of acne, oily skin, progressive macular hypomelanosis, dandruff, atopic eczema, atopic dermatitis, rosacea in a subject.

19 . The skin care composition of claim 1 , wherein the composition is capable of improving an appearance of skin of a subject and/or of modulating a sebum production of skin cells of a subject and/or of maintaining healthy skin of a subject.

20 . The skin care composition of claim 1 , wherein the composition further comprises (b5) one or more of ethanol, phenoxyethanol, caprylyl glycol, and methylpropanediol as preservative.