IP Library Granted Patent US 12685715
Granted Patent B2
US 12685715 · App. 18/237,920 · Granted Jul 21, 2026

Compositions, methods of treatment, and containers including compositions

Inventors: Anuj Chauhan (Gainesville, FL); Phillip J. Dixon (Gainesville, FL)
Assignee: University of Florida Research Foundation, INC.
A61K31/145A45C11/005A61F9/0008A61K9/0048A61K47/22A61K47/42
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Quick Facts
Patent No.
US 12685715
App. No.
18/237,920
Granted
Jul 21, 2026
Kind
B2
Abstract

Compositions for treatment of cystinosis, products for administering eye drops, and products for storing contact lenses are provided. Compositions include solutions that can contain an effective amount of cysteamine to treat cystinosis, and an oil with a lower density than the solution. Also provided is a product including a bottle for containing a solution, the bottle being substantially free of O 2 . Also provided is a contact lens holder for storing one or more contact lenses in a solution, the holder including barrier layers reducing the amount of O 2 entering the contact lens holder.

Claims (12)

1 . A product comprising a bottle containing a solution, wherein the bottle comprises at least one barrier layer, wherein an environment within the bottle not occupied by the solution is about 90% or more free of O 2 ; and

wherein the solution comprises an effective amount of cysteamine or derivatives thereof to treat cystinosis, and an oil having a lower density than the solution.

2 . The product of claim 1 , wherein the barrier layer includes a layer of ethylene vinyl alcohol, aluminum foil, and an iron based absorbent layer.

3 . The product of claim 1 , wherein the at least one barrier layer includes three barrier layers stacked on top of one another.

4 . The product of claim 1 , further comprising a container, wherein the bottle is disposed within the container, wherein the environment within the container is substantially free of O 2 .

5 . The product of claim 4 , wherein the container comprises at least one barrier layer, wherein each of the barrier layers reduces the amount of O 2 from entering the container as compared to a container without the barrier layer.

6 . The product of claim 5 , wherein the barrier layer includes a layer of ethylene vinyl alcohol, aluminum foil, and an iron based absorbent layer.

7 . The product of claim 6 , wherein the at least one barrier layer includes three barrier layers stacked on top of one another.

8 . The product of claim 4 , further comprising a tip having a one way valve so the solution exits the tip and air enters through a separate channel.

9 . The product of claim 8 , wherein the channel includes one or more chemicals to reduce the amount of O 2 entering the bottle.

10 . The product of claim 1 , further comprising a tip having a one way valve so the solution exits the tip and air enters through a separate channel.

11 . The product of claim 10 , wherein the channel includes one or more chemicals to reduce the amount of O 2 entering the bottle.