IP Library Granted Patent US 12685874
Granted Patent B2
US 12685874 · App. 18/213,673 · Granted Jul 21, 2026

Motor threshold detection device for use with a magnetic stimulation system

Inventors: Kenneth Ghiron (Malvern, PA); Dennis Michael Sauro (Douglassville, PA); Daniel Zangrilli (Ardmore, PA); Aaron M. Kern (Phoenixville, PA)
Assignee: Neuronetics, Inc.
A61N2/006A61N2/02
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Quick Facts
Patent No.
US 12685874
App. No.
18/213,673
Granted
Jul 21, 2026
Kind
B2
Abstract

A system may include a plurality of depressible members, wherein each depressible member is configured to move in response to movement of one or more digits of the subject. The system may include a plurality of sensors, wherein each depressible member is associated with at least one sensor, and wherein each sensor is configured to sense movement of at least one of the plurality of depressible members. The system may receive a feedback signal from each of the plurality of sensors, receive a signal that indicates a generation time of a magnetic stimulation pulse, and determine that the feedback signal from at least one of the plurality of sensors indicates movement within a time window after the generation time of the magnetic pulse. The system may generate, via a user interface, a notification that indicates that at least one of the depressible members moved in response to the magnetic pulse.

Claims (41)

1 . A system for detecting movement of a human subject when determining a position of a motor threshold or a treatment location of the human subject during a treatment or procedure, the system comprising:

a plurality of depressible members, wherein each depressible member is configured to move in response to movement of a finger of the human subject;

a plurality of sensors, wherein each depressible member is associated with at least one sensor, and wherein each sensor is configured to sense movement of at least one of the plurality of depressible members; and

a processor configured to:

receive a feedback signal from each of the plurality of sensors;

receive a signal that indicates a generation time of a magnetic stimulation pulse;

determine that the feedback signal from at least one of the plurality of sensors indicates movement above a threshold within a time window after the generation time of the magnetic stimulation pulse; and

generate, via a user interface, a notification that indicates that at least one of the plurality of depressible members moved in response to the magnetic stimulation pulse.

2 . The system of claim 1 , wherein the notification indicates an amount of movement of the at least one depressible member that moved in response to the magnetic stimulation pulse.

3 . The system of claim 2 , wherein the notification comprises a meter to indicate the amount of movement of the at least one depressible member that moved in response to the magnetic stimulation pulse.

4 . The system of claim 3 , wherein the meter comprises first indicia that indicates the amount of movement of the depressible member during a present magnetic stimulation pulse, and second indicia that indicates the amount of movement of the depressible member during a previously generated magnetic stimulation pulse.

5 . The system of claim 1 , wherein the plurality of depressible members comprises a first depressible member that is configured to receive a thumb of the human subject, wherein movement of the first depressible member indicates that a stimulation coil that generated the magnetic stimulation pulse is located at the motor threshold location of the human subject.

6 . The system of claim 5 , wherein the plurality of depressible members further comprises a second depressible member that is configured to receive an index finger and a middle finger of the human subject, and a third depressible member that is configured to receive a ring finger and a pinky finger of the human subject.

7 . The system of claim 1 , wherein the plurality of sensors comprise a plurality of accelerometers.

8 . The system of claim 1 , further comprising:

a base configured to receive the subject's palm, wherein the base is rigidly fixed and configured to remain steady during movement by the fingers of the human subject.

9 . The system of claim 1 , further comprising:

a plurality of spring arms, wherein each of the depressible members is associated with at least one spring arm, and wherein the spring arm is configured to allow the depressible member to move in response to movement of the finger of the human subject.

10 . The system of claim 1 , further comprising:

a user interface device, wherein the user interface device comprises the user interface.

11 . The system of claim 10 , wherein the user interface comprises a display device.

12 . The system of claim 1 , further comprising:

an electromagnet;

a drive circuit electrically coupled to the electromagnet; and

a second processor configured to control the drive circuit to provide current to the electromagnet to generate the magnetic stimulation pulse.

13 . The system of claim 12 , wherein the second processor is further configured to provide the signal that indicates the generation time of the magnetic stimulation pulse to the processor.

14 . A system for detecting movement of one or more bodies of a human subject, the movement being generated in response to a magnetic stimulation pulse, the system comprising:

a motion detection device comprising:

a plurality of depressible members operably coupled to a base member, wherein the plurality of depressible members is configured to move about the base member in response to a movement of a respective body of the human subject; and

a plurality of sensors, wherein each sensor is coupled to a respective depressible member of the plurality of depressible members, and wherein each sensor is configured to detect movement of the respective depressible member; and

a processor configured to:

receive sensor data associated with detected movement of one or more of the plurality of depressible members;

receive a signal that indicates a generation time of the magnetic stimulation pulse;

determine that the sensor data indicates movement of the one or more plurality of depressible members within a time window associated with the generation time of the magnetic stimulation pulse; and

generate a notification indicating that at least one of the depressible members moved in response to the magnetic stimulation pulse.

15 . The system of claim 13 , wherein the processor is comprised within the motion detection device.

16 . The system of claim 13 , wherein the processor is comprised with a treatment device that comprises a stimulation coil that is configured to generate the magnetic stimulation pulse.

17 . The system of claim 13 , wherein the processor is comprised within a user interface device that comprises a display device, wherein the processor is configured to generate the notification via the display device.

18 . The system of claim 13 , wherein the notification indicates an amount of movement of the at least one depressible member that moved in response to the magnetic stimulation pulse.

19 . The system of claim 13 , wherein the plurality of depressible members comprises a first depressible member that is configured to receive a thumb of the human subject, wherein movement of the first depressible member indicates that a stimulation coil that generated the magnetic stimulation pulse is located at the motor threshold location of the human subject.

20 . The system of claim 19 , wherein the plurality of depressible members further comprises a second depressible member that is configured to receive an index finger and a middle finger of the human subject, and a third depressible member that is configured to receive a ring finger and a pinky finger of the human subject.