Boron and nitrogen co-doped graphene oxide gels and uses thereof
The gel made of graphene oxide co-doped with boron nitrogen can be functionalized with a receptor, can be passivated by a passivation agent, and can have particular expressions of bonds to favor charge carrier mobility. The gel can be used in the context of a sensor via the interaction between the receptor and an analyte to be detected.
1 . A method of detecting a presence of an analyte adapted to a receptor in a sample, the method comprising applying the sample onto a gel made of graphene oxide co-doped with boron nitrogen, the gel having B—N bonds, the gel being functionalized with the receptor, the receptor being adapted to react with an analyte, the analyte being a molecule, the gel having a 3D structure, the method further comprising measuring an electrical characteristic of the gel during contact with the sample, and determining the presence of the analyte in the sample based on a change in the electrical characteristic, wherein the receptor is an amine-terminate receptor.
2 . The method of claim 1 , wherein the gel forms a channel of a field effect transistor, and wherein said measuring is performed with the field effect transistor.
3 . The method of claim 1 wherein the gel has at least 50% B—N bonds, less than 40% B—C bonds, at least 5% Pyridinic N bonds, less than 70% C—N—B bonds, less than 20% Pyrrolic N bonds.
4 . The method of claim 3 , wherein the gel comprises at least 15% Pyridinic N bonds.
5 . The method of claim 3 , wherein the gel comprises less than 60% C—N—B bonds.
6 . The method of claim 3 , wherein the gel comprises 0% Pyrrolic N bonds.
7 . The method of claim 3 wherein the gel has an ON and OFF current ratio of between 10 8 and 10 5 cm 2 V −1 s −1 .
8 . The method of claim 7 wherein the ON and OFF current ratio is between 10 8 cm 2 V −1 s −1 and 10 6 cm 2 V −1 s −1 .
9 . A method of detecting a presence of an analyte adapted to a receptor in a sample, the method comprising applying the sample onto a gel made of graphene oxide co-doped with boron nitrogen, the gel having B—N bonds, the gel being functionalized with the receptor, the receptor being adapted to react with an analyte, the analyte being a molecule, the gel having a 3D structure, the method further comprising measuring an electrical characteristic of the gel during contact with the sample, and determining the presence of the analyte in the sample based on a change in the electrical characteristic, wherein the gel further has a passivation agent, wherein the gel has carboxyl functional groups, the carboxyl functional groups functionalizing the receptor onto the gel, wherein the passivation agent is configured to bind with excess carboxyl functional groups.
10 . A method of detecting a presence of an analyte adapted to a receptor in a sample, the method comprising applying the sample onto a gel made of graphene oxide co-doped with boron nitrogen, the gel having B—N bonds, the gel being functionalized with the receptor, the receptor being adapted to react with an analyte, the analyte being a molecule, the gel having a 3D structure, the method further comprising measuring an electrical characteristic of the gel during contact with the sample, and determining the presence of the analyte in the sample based on a change in the electrical characteristic, wherein the gel further has a dielectric.