Multispectral photoacoustic devices
An apparatus may include a platen, a light source system, an ultrasonic receiver system and a control system, the light source system configured for providing first light of a first wavelength and second light of a second wavelength to a target object on an outer surface of the platen. The control system may be configured to: cause the light source system to provide the first light to the target object at a first time and to provide the second light to the target object at a second time; receive first ultrasonic receiver signals and second ultrasonic receiver signals from the ultrasonic receiver system corresponding to photoacoustic responses of the target object to the first light and the second light, respectively; and estimate one or more blood vessel features based on at least one of the first ultrasonic receiver signals or the second ultrasonic receiver signals.
1 . An apparatus, comprising:
a platen;
a light source system configured for providing light to a target object on an outer surface of the platen, the light including at least first light of a first wavelength emitted by a first light-emitting device and second light of a second wavelength emitted by a second light-emitting device, the light source system including a light guide system configured to convey the first light and the second light to the platen;
an ultrasonic receiver system configured to receive ultrasonic waves generated by the target object responsive to the light from the light source system; and
a control system configured to:
cause the light source system to provide the first light to the target object at a first time;
receive first ultrasonic receiver signals from the ultrasonic receiver system corresponding to photoacoustic responses of the target object to the first light;
cause the light source system to provide the second light to the target object at a second time;
receive second ultrasonic receiver signals from the ultrasonic receiver system corresponding to photoacoustic responses of the target object to the second light;
differentiate a desired signal from one or more background signals based, at least in part, on one or more amplitude differences between the first ultrasonic receiver signals and the second ultrasonic receiver signals; and
estimate one or more blood vessel features based on at least one of the first ultrasonic receiver signals or the second ultrasonic receiver signals.
2 . The apparatus of claim 1 , wherein the one or more background signals correspond to electromagnetic interference or skin.
3 . The apparatus of claim 1 , wherein the desired signal corresponds to a blood vessel within the target object.
4 . The apparatus of claim 1 , wherein the one or more blood vessel features include blood vessel diameter, blood vessel area, blood vessel profile, blood vessel distention, volumetric flow, pulse wave velocity, blood vessel wall thickness, or combinations thereof.
5 . The apparatus of claim 1 , wherein the control system is further configured to estimate blood pressure based, at least in part, on the one or more blood vessel features.
6 . The apparatus of claim 1 , wherein the first light-emitting device comprises a first laser configured to emit the first light and the second light-emitting device comprises a second laser configured to emit the second light.
7 . The apparatus of claim 1 , wherein a first light guide portion of the light guide system resides between at least two ultrasonic receiver system portions.
8 . The apparatus of claim 7 , wherein the light guide system includes a second light guide portion configured to convey the first light to the first light guide portion and a third light guide portion configured to convey the second light to the first light guide portion.
9 . The apparatus of claim 1 , wherein at least a portion of the ultrasonic receiver system is arranged in a ring around a first light guide portion.
10 . The apparatus of claim 1 , wherein the light guide system includes a light guide configured to convey light in a direction that is parallel to, or substantially parallel to, the platen, wherein “substantially parallel to” means within 20 degrees of being parallel.
11 . The apparatus of claim 10 , wherein the light guide system includes a plurality of light extracting elements residing within the light guide, the light extracting elements being configured to direct light towards the platen.
12 . The apparatus of claim 1 , wherein the ultrasonic receiver system includes a linear array of ultrasonic receiver elements, a two-dimensional array of ultrasonic receiver elements, or both.
13 . The apparatus of claim 1 , wherein the ultrasonic receiver system includes an array of transparent ultrasonic receiver elements, a transparent piezoelectric layer, a transparent electrode layer, or combinations thereof.
14 . The apparatus of claim 1 , wherein the light source system is configured for providing the first light to the target object along a first axis and is configured for providing the second light to the target object along the first axis.
15 . The apparatus of claim 14 , wherein the ultrasonic receiver system receives acoustic waves from the target object along a second axis that is different from the first axis, the acoustic waves corresponding to the first ultrasonic receiver signals and the second ultrasonic receiver signals.
16 . The apparatus of claim 15 , wherein the second axis is separated from the first axis by an angle in a range from 10 degrees to 60 degrees.