Mechanical thrombectomy device partially collapsible during retrieval of an occlusion upon activation of an internal actuatable collapsing mechanism

1 . A mechanical thrombectomy device comprising:

a self-expanding cage structure transitionable from a radially expanded state to a radially partially collapsed state of reduced outer diameter relative to that while in the radially expanded state; and

an internal actuatable collapsing mechanism fixedly attached internally to the self-expanding cage structure; wherein the internal actuatable collapsing mechanism when actuated imposes a radially inward tension on the self-expanding cage structure transitioning to the radially partially collapsed state;

wherein the internal actuatable collapsing mechanism is at least one pull wire including a main section and a plurality of branch sections with each branch section having a first end connected to the main section and an opposite second end fixedly connected internally to the self-expanding cage structure.

2 . The mechanical thrombectomy device according to claim 1 , wherein the main section and the plurality of branch sections comprising the at least one pull wire are formed from a single piece of wire or multiple wire sections fixedly secured together to form a single unit.

3 . A mechanical thrombectomy device comprising:

a self-expanding cage structure transitionable from a radially expanded state to a radially partially collapsed state of reduced outer diameter relative to that while in the radially expanded state; and

an internal actuatable collapsing mechanism fixedly attached internally to the self-expanding cage structure; wherein the internal actuatable collapsing mechanism when actuated imposes a radially inward tension on the self-expanding cage structure transitioning to the radially partially collapsed state;

wherein the self-expanding cage structure comprises a plurality of articulated scaffolding sections; and the internal actuatable collapsing mechanism is at least one pull wire including a main section and a plurality of branch sections; each of the plurality of branch sections has a first end connected to the main section and an opposite second end fixedly connected internally to one of the plurality of articulated scaffolding sections.

4 . The mechanical thrombectomy device according to claim 3 , wherein every one of the plurality of articulated scaffolding sections has associated therewith one of the plurality of branch sections internally attached thereto.

5 . The mechanical thrombectomy device according to claim 3 , wherein the internal actuatable collapsing mechanism is a plurality of pull wires independently actuatable of each other; each of the plurality of pull wires is connected internally to a different one of the plurality of articulated scaffolding sections.

6 . A mechanical thrombectomy device comprising:

a self-expanding cage structure transitionable from a radially expanded state to a radially partially collapsed state of reduced outer diameter relative to that while in the radially expanded state; and

an internal actuatable collapsing mechanism fixedly attached internally to the self-expanding cage structure; wherein the internal actuatable collapsing mechanism when actuated imposes a radially inward tension on the self-expanding cage structure transitioning to the radially partially collapsed state;

wherein the internal actuatable collapsing mechanism is a plurality of pull wires independently actuatable of each other; and wherein the self-expanding cage structure comprises a dual structure including an inner self-expanding cage structure disposed within an inner axial channel of an outermost self-expanding cage structure, wherein each self-expanding cage structure is independently deployable of one another; and the plurality of pull wires includes a first pull wire attached internally to the outermost self-expanding cage structure and a second pull wire attached internally to the inner self-expanding cage structure; wherein the first and second pull wires are actuatable independently of one another to radially partially collapse a respective one of the outermost self-expanding cage structure and/or inner self-expanding cage structure.

7 . A method for capture and retrieval of an occlusion in a vessel using a mechanical thrombectomy device having a self-expanding cage structure transitionable from a radially expanded state to a radially partially collapsed state of reduced outer diameter relative to that while in the radially expanded state; and the mechanical thrombectomy device further including an internal actuatable collapsing mechanism fixedly attached internally to the self-expanding cage structure; and wherein the internal actuatable collapsing mechanism when actuated imposes a radially inward tension on the self-expanding cage structure transitioning to the radially partially collapsed state, the method comprising:

inserting a guidewire though the vessel to a proximal side of the occlusion;

tracking a microcatheter over the guidewire to the proximal side of the occlusion;

together or independently one-after-the other, advancing the guidewire and microcatheter through the occlusion;

withdrawing the guidewire from the vessel;

advancing the mechanical thrombectomy device through the microcatheter;

actuating the mechanical thrombectomy device thereby transitioning to the radially expanded state and capturing the occlusion therein;

actuating the internal actuatable collapsing mechanism imposing a radially inward tension internally within the self-expanding cage structure thereby transitioning from the radially expanded state to the radially partially collapsed state reduced in outer diameter while compressing the occlusion captured therein; and

with the compressed occlusion captured therein, drawing back into the microcatheter the self-expanding cage structure while in in the radially partially collapsed state;

wherein the internal actuatable collapsing mechanism is at least one pull wire including a main section and a plurality of branch sections with each branch section having a first end connected to the main section and an opposite second end connected internally to the self-expanding cage structure.

8 . The method according to claim 7 , wherein the main section and the plurality of branch sections comprising the at least one pull wire are formed from a single piece of wire or multiple wire sections fixedly secured together to form a single unit.

9 . A method for capture and retrieval of an occlusion in a vessel using a mechanical thrombectomy device having a self-expanding cage structure transitionable from a radially expanded state to a radially partially collapsed state of reduced outer diameter relative to that while in the radially expanded state; and the mechanical thrombectomy device further including an internal actuatable collapsing mechanism fixedly attached internally to the self-expanding cage structure; and wherein the internal actuatable collapsing mechanism when actuated imposes a radially inward tension on the self-expanding cage structure transitioning to the radially partially collapsed state, the method comprising:

inserting a guidewire though the vessel to a proximal side of the occlusion;

tracking a microcatheter over the guidewire to the proximal side of the occlusion;

together or independently one-after-the other, advancing the guidewire and microcatheter through the occlusion;

withdrawing the guidewire from the vessel;

advancing the mechanical thrombectomy device through the microcatheter;

actuating the mechanical thrombectomy device thereby transitioning to the radially expanded state and capturing the occlusion therein;

actuating the internal actuatable collapsing mechanism imposing a radially inward tension internally within the self-expanding cage structure thereby transitioning from the radially expanded state to the radially partially collapsed state reduced in outer diameter while compressing the occlusion captured therein; and

with the compressed occlusion captured therein, drawing back into the microcatheter the self-expanding cage structure while in in the radially partially collapsed state;

wherein the self-expanding cage structure comprises a plurality of articulated scaffolding sections; and the internal actuatable collapsing mechanism is at least one pull wire including a main section and a plurality of branch sections; each of the plurality of branch sections has a first end connected to the main section and an opposite second end connected internally to one of the plurality of articulated scaffolding sections.

10 . The method according to claim 9 , wherein every one of the plurality of articulated scaffolding sections has associated therewith one of the plurality of branch sections internally attached thereto.

11 . The method according to claim 9 , wherein the internal actuatable collapsing mechanism is a plurality of pull wires independently actuatable of each other; each of the plurality of pull wires is connected internally to a different one of the plurality of articulated scaffolding sections.

12 . The method according to claim 11 , wherein actuating comprises independently controlling an amount of tension imposed in a proximal direction on each of the plurality of pull wires independently regulating an extent of reduction in the outer diameter when transitioned to the radially partially collapsed state for each one of the plurality of articulated scaffolding sections connected thereto.

13 . A method for capture and retrieval of an occlusion in a vessel using a mechanical thrombectomy device having a self-expanding cage structure transitionable from a radially expanded state to a radially partially collapsed state of reduced outer diameter relative to that while in the radially expanded state; and the mechanical thrombectomy device further including an internal actuatable collapsing mechanism fixedly attached internally to the self-expanding cage structure; and wherein the internal actuatable collapsing mechanism when actuated imposes a radially inward tension on the self-expanding cage structure transitioning to the radially partially collapsed state, the method comprising:

inserting a guidewire though the vessel to a proximal side of the occlusion;

tracking a microcatheter over the guidewire to the proximal side of the occlusion;

together or independently one-after-the other, advancing the guidewire and microcatheter through the occlusion;

withdrawing the guidewire from the vessel;

advancing the mechanical thrombectomy device through the microcatheter;

actuating the mechanical thrombectomy device thereby transitioning to the radially expanded state and capturing the occlusion therein;

actuating the internal actuatable collapsing mechanism imposing a radially inward tension internally within the self-expanding cage structure thereby transitioning from the radially expanded state to the radially partially collapsed state reduced in outer diameter while compressing the occlusion captured therein; and

with the compressed occlusion captured therein, drawing back into the microcatheter the self-expanding cage structure while in in the radially partially collapsed state;

wherein the self-expanding cage structure comprises a dual structure including an inner self-expanding cage structure disposed within an inner axial channel of an outermost self-expanding cage structure, wherein each self-expanding cage structure is independently deployable of one another; and the internal actuatable collapsing mechanism is a plurality of pull wires independently actuatable of each other and the plurality of pull wires includes a first pull wire attached internally to the outermost self-expanding cage structure and a second pull wire attached internally to the inner self-expanding cage structure; wherein the actuating step comprises independently pulling in a proximal direction the first and/or second pull wires respectively imposing internal tension within thereby transitioning to the radially partially collapsed state a respective one of the outermost self-expanding cage structure and/or inner self-expanding cage structure.

14 . The method according to claim 13 , wherein actuating further comprises independently controlling an amount of tension imposed in a proximal direction on each of the first and second pull wires independently regulating an extent of reduction in the outer diameter when transitioned to the radially partially collapsed state for each of the outermost self-expanding cage structure and/or the inner self-expanding cage structure connected thereto.