IP Library Granted Patent US 12691156
Granted Patent B2
US 12691156 · App. 18/348,364 · Granted Jul 28, 2026

Prebiotic compositions and method for promoting growth of

Inventors: Yung-Hsiang Lin (Taipei, TW); Di Chang (Taipei, TW)
Assignee: TCICO., LTD.
A61K36/82A61K8/9789A61K36/736A61K38/04A61K38/168A61P3/04A61Q19/08A61K2236/17A61K2236/19A61K2800/522
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Quick Facts
Patent No.
US 12691156
App. No.
18/348,364
Granted
Jul 28, 2026
Kind
B2
Abstract

A prebiotic composition includes a black tea ferment and a bioactive substance. The bioactive substance is soybean peptide powder, pea protein, rice protein, corn oligopeptide powder, or a combination thereof. The black tea ferment is prepared by the following steps: extracting tea leaves of Camellia sinensis with water at 50° C. to 100° C. for 0.5 hours to 3 hours to obtain a black tea extract, and fermenting the black tea extract with Saccharomyces cerevisiae BCRC20271, Bifidobacterium lactis BCRC910887, Lactobacillus gasseri BCRC910886, and Gluconacetobacter xylinus BCRC12335 for 12 days to 25 days to obtain the black tea ferment.

Claims (14)

1 . A method for weight loss of a subject in need thereof, comprising: administering an effective dose of a prebiotic composition to the subject, the prebiotic composition comprising a black tea ferment and a bioactive substance, a weight ratio of the black tea ferment to the bioactive substance being 9:1 to 1:9, the bioactive substance being soybean peptide powder, pea protein, rice protein, corn oligopeptide powder, or a combination thereof, and the black tea ferment being prepared by the following steps:

extracting tea leaves of Camellia sinensis with water at 50° C. to 100° C. for 0.5 hours to 3 hours to obtain a black tea extract; and

fermenting the black tea extract with Saccharomyces cerevisiae BCRC20271, Bifidobacterium lactis BCRC 910887, Lactobacillus gasseri BCRC910886, and Gluconacetobacter xylinus BCRC12335 for 12 days to 25 days to obtain the black tea ferment;

wherein the effect of weight loss is achieved by promoting growth of Hafnia alvei in the intestinal tract of the subject.

2 . The method according to claim 1 , wherein the prebiotic composition further comprises erythritol, Arabic gum, or a combination thereof.

3 . The method according to claim 2 , wherein a weight ratio of the black tea ferment to the bioactive substance to erythritol or Arabic gum is 1:1:0.05-2.

4 . The method according to claim 2 , wherein a weight ratio of the black tea ferment to the bioactive substance to erythritol to Arabic gum is 3:3:3.6:0.4.

5 . The method according to claim 1 , wherein the bioactive substance is the soybean peptide powder.

6 . The method according to claim 1 , wherein the prebiotic composition has an ability to increase the content of short-chain fatty acids in intestinal tracts.

7 . The method according to claim 1 , wherein the prebiotic composition has an ability to inhibit appetite of the subject.

8 . The method according to claim 1 , wherein the prebiotic composition has an ability to lose weight, and reduce body fat and waist circumference of the subject.

9 . The method according to claim 8 , wherein the body fat is trunk body fat.

10 . The method according to claim 1 , wherein the effective dose of the prebiotic composition is 500 g.

11 . The method according to claim 10 , wherein the prebiotic composition is administered twice a day.