IP Library Granted Patent US 12691213
Granted Patent B2
US 12691213 · App. 18/744,094 · Granted Jul 28, 2026

Medical device packaging and related methods

Inventors: Bryan C. Grygus (Clifton Park, NY); Jim Fedor (Bayport, MN); Wayne Phillips (Hudson, WI); Anne Wespetal (Menomonie, WI); Ashley Johannes (Halfmoon, NY); Tanya Magana (Richmond, WI)
Assignee: Regeneron Pharmaceuticals, Inc.
A61M5/002
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Quick Facts
Patent No.
US 12691213
App. No.
18/744,094
Granted
Jul 28, 2026
Kind
B2
Abstract

A packaging comprising a tray having a body surrounding an exposed cavity and a groove; a lip surrounding the opening, wherein the lip extends radially outward from the cavity and defines a periphery of the tray; a retainer for covering a portion of the opening of the tray, the retainer having an aperture, wherein the aperture corresponds to the groove of the tray; a removable cover; and an auto-injector contained within the cavity, wherein the auto-injector is pre-filed with a medicament or other fluid.

Claims (33)

1 . A packaging comprising:

a tray having a body surrounding an exposed cavity, an opening and a groove;

a lip surrounding the opening, wherein the lip extends radially outward from the cavity and defines a periphery of the tray;

a retainer for covering a portion of the opening of the tray, the retainer having an aperture, wherein the aperture corresponds to the groove of the tray;

a removable cover; and

an auto-injector contained within the cavity, wherein the auto-injector is pre-filed with a medicament or other fluid.

2 . The packaging of claim 1 , further comprising a gaseous sterilant.

3 . The packaging of claim 2 , wherein the gaseous sterilant includes one or more of ethylene oxide, vaporized hydrogen peroxide, ethyl alcohol, nitrous oxide, or nitrogen dioxide.

4 . The packaging of claim 1 , wherein the tray includes a first plurality of sidewalls and a second plurality of sidewalls.

5 . The packaging of claim 1 , further comprising a lug.

6 . The packaging of claim 1 , wherein the lip includes an adhesive and forms a seal with the retainer to enclose the auto-injector within the cavity.

7 . The packaging of claim 1 , wherein the tray and/or the retainer includes one or more of polypropylene, polystyrene, polyethylene, polycarbonate, polyvinyl chloride, or polyethylene terephthalate glycol.

8 . The packaging of claim 1 , wherein the removable cover includes high-density polyethylene fibers, thermoplastic materials, or a combination thereof.

9 . The packaging of claim 1 , wherein the medicament or fluid comprises one or more of dupilumab and cemiplimab.

10 . A packaging for an auto-injector, the packaging comprising:

a tray having an opening and a cavity;

a lip surrounding the opening, wherein the lip extends radially outward from the cavity and defines a periphery of the tray;

a removable cover having a periphery that is adhered to the lip; and

a retainer for covering a portion of the opening of the tray.

11 . The packaging of claim 10 , wherein the removable cover is permeable to a gaseous sterilant.

12 . The packaging of claim 10 , wherein the gaseous sterilant includes one or more of ethylene oxide, vaporized hydrogen peroxide, ethyl alcohol, nitrous oxide, or nitrogen dioxide.

13 . The packaging of claim 10 , wherein the tray and/or the retainer includes one or more of polypropylene, polystyrene, polyethylene, polycarbonate, polyvinyl chloride, or polyethylene terephthalate glycol.

14 . The packaging of claim 10 , wherein the removable cover includes high-density polyethylene fibers, thermoplastic materials, or a combination thereof.

15 . The packaging of claim 10 , wherein the auto-injector contains a medicament comprising one or more of dupilumab and cemiplimab.

16 . A method of removing an externally-sterilized auto-injector from a packaging, the packaging including a tray having an opening and a cavity, a retainer, a removable cover, and a gaseous sterilant, the method comprising:

removing the removable cover to expose the retainer;

removing the retainer to expose the cavity of the tray;

grasping a portion of the externally-sterilized auto-injector held within the cavity of the tray; and

ejecting the externally-sterilized auto-injector from the tray.

17 . The method of claim 16 , further comprising pushing a portion of the tray towards the cavity of the tray, wherein pushing the portion of the tray causes a portion of the tray to flex.

18 . The method of claim 17 , wherein pushing the portion of the tray causes the externally-sterilized auto-injector to release from the cavity of the tray.

19 . The method of claim 18 , wherein the gaseous sterilant includes one or more of ethylene oxide, vaporized hydrogen peroxide, ethyl alcohol, nitrous oxide, or nitrogen dioxide.

20 . The method of claim 19 , wherein the externally-sterilized auto-injector contains a medicament comprising one or more of dupilumab and cemiplimab.