IP Library Granted Patent US 12691295
Granted Patent B2
US 12691295 · App. 18/475,931 · Granted Jul 28, 2026

System and method for maintaining TTFields during battery changes

Inventor: Yoram Wasserman (Haifa, IL)
Assignee: Novocure GmbH
A61N1/40H01M10/425H01M2220/30H02J7/82
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Quick Facts
Patent No.
US 12691295
App. No.
18/475,931
Granted
Jul 28, 2026
Kind
B2
Abstract

An electronic apparatus is herein disclosed. The electronic apparatus comprises: an electric field generator providing a first electrical signal having a first alternating current waveform at a frequency between 50 kHz and 1 MHz; and a controller communicating with the electric field generator, the controller having an input, a processor, and a memory storing an accelerated power-up program, a standard power-up program, and computer-executable instructions that cause the processor to: receive a generator power-down event by the input; detect the generator power-down event; deactuate the electric field generator; store an operating parameter; determine an operating status based at least in part on the operating parameter; and actuate the electric field generator to provide a second electrical signal using the accelerated power-up program responsive to the operating status being the accelerated status; the second electrical signal having a second alternating current waveform at a frequency between 50 kHz and 1 MHz.

Claims (42)

1 . An electronic apparatus, comprising:

an electric field generator configured to provide a first electrical signal having a first alternating current waveform at a frequency in a range from 50 KHz to 1 MHz; and

a controller communicating with the electric field generator to control an output of the electric field generator, the controller having an input, a processor and a non-transitory computer-readable medium storing an accelerated power-up program, a standard power-up program, and computer-executable instructions that when executed by the processor cause the processor to:

receive a generator power-down event by the input, the generator power-down event being a physical interaction with the input;

detect the generator power-down event;

deactuate the electric field generator so as to cease providing the first electrical signal;

store an operating parameter indicative of an operation of the electric field generator or cessation of operation of the electric field generator;

determine an operating status based at least in part on the operating parameter, the operating status being one of an accelerated status and a standard status, the accelerated status indicating that the accelerated power-up program should be executed, and the standard status indicating that the standard power-up program should be executed;

wherein the accelerated power-up program includes computer-executable instructions that when executed by the processor responsive to the operating status being the accelerated status cause the processor to transmit a first control signal to the electric field generator to cause the electric field generator to increase a power of a second alternating current waveform to an operating power over a first time period;

wherein the standard power-up program includes computer-executable instructions that when executed by the processor responsive to the operating status being the standard status cause the processor to transmit a second control signal to the electric field generator to cause the electric field generator to increase a power of a third alternating current waveform to the operating power over a second time period;

wherein, the first time period is less than the second time period; and

actuate the electric field generator to provide:

i) a second electrical signal, using the accelerated power-up program responsive to the operating status being the accelerated status, the second electrical signal having the second alternating current waveform at a frequency in the range from 50 kHz to 1 MHz to generate a Tumor Treating Field (TTField); or

ii) a third electrical signal, using the standard power-up program responsive to the operating status being the standard status, the third electrical signal having the third alternating current waveform at a frequency in the range from 50 kHz to 1 MHZ to generate the TTField.

2 . The electronic apparatus of claim 1 , wherein the electric field generator further comprises at least one electrode array port and is further configured to supply power to the at least one electrode array port.

3 . The electronic apparatus of claim 1 , wherein the generator power-down event includes a generator battery change event that is triggered by one or more of removal of a first generator battery and insertion of a second generator battery.

4 . The electronic apparatus of claim 1 , wherein the computer-executable instructions further comprise instructions that when executed by the processor cause the processor to store the operating parameter indicative of a deactivation duration of the electric field generator, and

wherein determining the operating status includes determining the operating status is the accelerated status when the deactivation duration is below a predetermined deactivation duration threshold.

5 . The electronic apparatus of claim 4 , wherein the predetermined deactivation duration threshold is 5 minutes.

6 . The electronic apparatus of claim 1 , wherein the standard power-up program includes computer-executable instructions that when executed by the processor responsive to the operating status being the standard status cause the processor to transmit a control signal to the electric field generator to cause the electric field generator to set an initial power of the third alternating current waveform to less than 95% of an operating power.

7 . The electronic apparatus of claim 1 , wherein the accelerated power-up program includes computer-executable instructions that when executed by the processor responsive to the operating status being the accelerated status cause the processor to transmit a control signal to the electric field generator to cause the electric field generator to set a power of the second alternating current waveform to between an operating power and 95% of the operating power, inclusive.

8 . The electronic apparatus of claim 1 , wherein the electric field generator is connected to a first electrode array and a second electrode array, and wherein the computer-executable instructions further comprise instructions that when executed by the processor cause the processor to monitor disconnection of at least one of the first electrode array and the second electrode array wherein, upon detection of a disconnection of at least one of the first electrode array and the second electrode array, the operating status is set to the standard status.

9 . The electronic apparatus of claim 1 , further comprising:

a first electrode array; and

a second electrode array; and

wherein the electric field generator is connected to the first electrode array and the second electrode array, and wherein the computer-executable instructions further comprise instructions that when executed by the processor cause the processor to:

store a measurement of circuit resistance as the operating parameter; and

monitor a circuit resistance during a period of time in which the electric field generator is deactuated.

10 . The electronic apparatus of claim 9 , wherein when the monitored circuit resistance differs from the measured circuit resistance stored as the operating parameter by more than a resistance threshold, the operating status is set to the standard status.

11 . A method, comprising:

storing an operating parameter, the operating parameter being indicative of an operation of an electric field generator or cessation of operation of the electric field generator, the electric field generator configured to provide a first electrical signal having a first alternating current waveform at a frequency in a range from 50 kHz to 1 MHz;

deactuating the electric field generator so as to cease providing a first electrical signal;

determining an operating status based at least in part on the operating parameter, the operating status being one of an accelerated status and a standard status, the accelerated status indicating that an accelerated power-up program should be executed by a processor, and the standard status indicating that a standard power-up program should be executed by the processor, wherein the accelerated power-up program includes computer-executable instructions that when executed by the processor, responsive to the operating status being the accelerated status, cause the processor to transmit a first control signal to the electric field generator to cause the electric field generator to increase a power of a second alternating current waveform to an operating power over a first time period, wherein the standard power-up program includes computer-executable instructions that when executed by the processor, responsive to the operating status being the standard status, cause the processor to transmit a second control signal to the electric field generator to cause the electric field generator to increase a power of a third alternating current waveform to the operating power over a second time period, wherein, the first time period is less than the second time period; and;

actuating the electric field generator to provide:

i) a second electrical signal, using the accelerated power-up program responsive to the operating status being an accelerated status, the second electrical signal having the second alternating current waveform at a frequency in the range from 50 kHz to 1 MHz to generate a Tumor Treating Field (TTField); or

ii) a third electrical signal, using the standard power-up program responsive to the operating status being the standard status, the third electrical signal having the third alternating current waveform at a frequency in the range from 50 kHz to 1 MHz to generate the TTField.

12 . The method of claim 11 , wherein actuating the electric field generator to provide the second electrical signal further comprises actuating the electric field generator to provide the second electrical signal having the second alternating current waveform with a second power greater than a third power of the third electrical signal.

13 . The method of claim 11 , further comprising detecting installation of a generator battery prior to determining an operating status.

14 . The method of claim 11 , further comprising comparing an amount of charge of a first generator battery to an amount of charge of a second generator battery prior to actuating the electric field generator to provide the second electrical signal and prior to actuating the electric field generator to provide the third electrical signal, wherein the second generator battery is a backup battery or a replacement battery for the first generator battery.

15 . The method of claim 14 , wherein determining the operating status includes setting the operating status to a warning status when the amount of charge of the second generator battery is within 5% of the amount of charge of the first generator battery, and further comprising transmitting a signal indicative of the warning status.

16 . The method of claim 11 , wherein storing the operating parameter further comprises storing data indicative of at least one of a circuit resistance, a voltage of the first alternating current waveform, and a current of the first alternating current waveform prior to deactuating the electric field generator.

17 . The method of claim 16 , wherein actuating the electric field generator to provide the second electrical signal is further defined as actuating the electric field generator to provide the second electrical signal based upon the operating parameter wherein either a second initial voltage of the second alternating current waveform or a second current of the second alternating current waveform is selected such that a second power of the second alternating current waveform is between a power of the first alternating current waveform and 95% of the power of the first alternating current waveform.