IP Library › Granted Patent US 12693297
Granted Patent B2
US 12693297 · App. 17/203,802 · Granted Jul 28, 2026

Coumarin-based crosslinking reagents

Inventors: Rui Hong (Oro Valley, AZ); Mark Lefever (Oro Valley, AZ); Eric May (Oro Valley, AZ)
Assignee: Ventana Medical Systems, Inc.
G01N33/583C09B57/02C09B69/109
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Quick Facts
Patent No.
US 12693297
App. No.
17/203,802
Granted
Jul 28, 2026
Kind
B2
Abstract

Disclosed herein are novel coumarin-based reagents, e.g. linkers, and conjugates including one or more of the disclosed coumarin-based reagents. In some embodiments, the presence of a coumarin moiety within the coumarin-based reagents enables detection of labels which are typically difficult to detect, e.g. certain haptens.

Claims (3)

1 . A compound selected from the group consisting of

2 . A compound selected from the group consisting of

3 . A compound selected from the group consisting of