Physiological resilience-maintaining formulations

1 . A formulation for maintaining physiological resilience during conditions of sustained physical activity, comprising:

a carbohydrate blend of simple and complex carbohydrates providing less than 70% of total calories of a complete meal in a complete meal-equivalent (“CME”) dose of the formulation;

a fatty-acid blend of medium-chain fatty acids (“MCFAs”), long-chain fatty acids (“LCFAs”), and very-long-chain fatty acids (“VLCFAs”), optionally including homo- or heterotriglycerides thereof, the fatty-acid blend providing less than 50% of the total calories of the complete meal in the CME dose of the formulation; and

an amino-acid blend of essential amino acids (“EAAs”), the EAAs providing 60-80% by weight of the amino-acid blend, and the EAAs providing less than 30% of the total calories of the complete meal in the CME dose of the formulation, the formulation formulated in a powder form such that the CME dose of the formulation dissolves in 5 oz of fluid water.

2 . The formulation of claim 1 , wherein the carbohydrate blend includes fructose as a simple carbohydrate, the fructose providing 2-15% of the total calories of the complete meal in the CME dose of the formulation.

3 . The formulation of claim 1 , wherein the carbohydrate blend includes maltodextrin as a complex carbohydrate, the maltodextrin providing 5-25% of the total calories of the complete meal in the CME dose of the formulation.

4 . The formulation of claim 1 , wherein the fatty-acid blend includes at least a portion of the MCFAs as medium-chain triglycerides (“MCTs”), the MCTs providing 20-25% by weight of the fatty-acid blend.

5 . The formulation of claim 1 , wherein the fatty-acid blend includes at least a portion of the LCFAs and VLCFAs as omega-3 fatty acids selected from oleic acid (“OA”), eicosapentaenoic acid (“EPA”), and docosahexaenoic acid (“DHA”), the OA, EPA, and DHA respectively providing 45-55%, 2-10%, and 15-20% by weight of the fatty-acid blend.

6 . The formulation of claim 1 , wherein a portion of the EAAs is derived from Plukenetia volubilis , the portion of the EAAs from P. volubilis providing 10-20% by weight of the amino-acid blend, and the portion of the EAAs from P. volubilis providing less than 3% of the total calories of the complete meal in the CME dose of the formulation.

7 . The formulation of claim 1 , wherein the EAAs include L-isoleucine providing 5-10% by weight of the formulation; L-lysine providing 15-20% by weight of the formulation; L-methionine providing 3-8% by weight of the formulation; L-phenylalanine providing 4-8% by weight of the formulation; L-valine providing 6-10% by weight of the formulation; L-histidine providing 3-6% by weight of the formulation; L-threonine providing 6-10% by weight of the formulation; L-tryptophan providing up to 3% by weight of the formulation; L-leucine providing 15-20% by weight of the amino-acid blend, or a combination thereof.

8 . The formulation of claim 1 , wherein at least the EAAs are instantized.

9 . The formulation of claim 1 , wherein the amino-acid blend includes non-essential amino acids (“NEAAs”), the NEAAs including L-alanine, L-arginine, L-aspartate, L-cysteine, cystine, L-glutamate, L-glycine, L-proline, L-serine, L-glutamine, or a combination thereof, the NEAAs providing 5-10% by weight of the amino-acid blend, and the NEAAs providing less than 3% of the total calories of the complete meal in the CME dose of the formulation.

10 . The formulation of claim 1 , wherein the amino-acid blend further includes 1-3 g of L-citrulline in the CME dose of the formulation.

11 . The formulation of claim 1 , wherein the total calories of the complete meal in the CME dose of the formulation are 670-830 calories.

12 . The formulation of claim 1 , further comprising one or more flavoring agents, one or more sweeteners, or some combination thereof, any of the one-or-more flavoring agents or the one-or-more sweeteners incorporated into an outer layer of powder particles of the formulation.

13 . A method of using a formulation to maintain physiological resilience during conditions of sustained physical activity, comprising:

obtaining a packaged formulation including at least a complete meal-equivalent (“CME”) dose of the formulation in a package, the formulation including:

a carbohydrate blend of simple and complex carbohydrates providing less than 70% of total calories of a complete meal in a complete meal-equivalent (“CME”) dose of the formulation;

a fatty-acid blend of medium-chain fatty acids (“MCFAs”), long-chain fatty acids (“LCFAs”), and very-long-chain fatty acids (“VLCFAs”), optionally including homo- or heterotriglycerides thereof, the fatty-acid blend providing less than 50% of the total calories of the complete meal in the CME dose of the formulation; and

an amino-acid blend of essential amino acids (“EAAs”), the EAAs providing 60-80% by weight of the amino-acid blend, and the EAAs providing less than 30% of the total calories of the complete meal in the CME dose of the formulation;

opening the package of the packaged formulation;

dispensing the CME dose of the formulation into a receptacle, the formulation formulated in a powder form;

dissolving the CME dose of the formulation in 5 oz of fluid water to form an aqueous solution of the formulation; and

consuming the aqueous solution of the formulation.

14 . The method of claim 13 , wherein the carbohydrate blend includes fructose as a simple carbohydrate, the fructose providing 2-15% of the total calories of the complete meal in the CME dose of the formulation.

15 . The method of claim 13 , wherein the carbohydrate blend includes maltodextrin as a complex carbohydrate, the maltodextrin providing 5-25% of the total calories of the complete meal in the CME dose of the formulation.

16 . The method of claim 13 , wherein the fatty-acid blend includes at least a portion of the MCFAs as medium-chain triglycerides (“MCTs”), the MCTs providing 20-25% by weight of the fatty-acid blend.

17 . The method of claim 13 , wherein the fatty-acid blend includes at least a portion of the LCFAs and VLCFAs as omega-3 fatty acids selected from oleic acid (“OA”), eicosapentaenoic acid (“EPA”), and docosahexaenoic acid (“DHA”).

18 . The method of claim 17 , wherein the OA, EPA, and DHA respectively provide 45-55%, 2-10%, and 15-20% by weight of the fatty-acid blend.

19 . The method of claim 13 , wherein a portion of the EAAs is derived from Plukenetia volubilis , the portion of the EAAs from P. volubilis providing 10-20% by weight of the amino-acid blend, and the portion of the EAAs from P. volubilis providing less than 3% of the total calories of the complete meal in the CME dose of the formulation.

20 . The method of claim 13 , wherein the EAAs include L-isoleucine providing 5-10% by weight of the formulation; L-lysine providing 15-20% by weight of the formulation; L-methionine providing 3-8% by weight of the formulation; L-phenylalanine providing 4-8% by weight of the formulation; L-valine providing 6-10% by weight of the formulation; L-histidine providing 3-6% by weight of the formulation; L-threonine providing 6-10% by weight of the formulation; L-tryptophan providing up to 3% by weight of the formulation; L-leucine providing 15-20% by weight of the amino-acid blend, or a combination thereof.