Cannabinoid lipid premixture
The invention relates to a powder premixture for oral administration of cannabinoids, comprising a cannabinoid powder composition comprising one or more isolated cannabinoids in an amount of at least 2% by weight of the powder premixture; a lipid composition comprising one or more triglycerides in an amount of at least 1.0% by weight of the powder premixture; and a sweetener powder composition comprising one or more sweeteners, wherein the weight ratio between the one or more triglycerides and the one or more sweeteners is in the range of 1:50 to 1:4.
1 . A method of producing a powder premixture for oral administration of cannabinoids, the method comprising the steps of:
i) providing
a cannabinoid powder composition comprising one or more isolated cannabinoids in an amount of at least 2% by weight of the powder premixture;
a lipid composition comprising one or more triglycerides in an amount of at least 1.0% by weight of the powder premixture; and
a sweetener powder composition comprising one or more sweeteners,
wherein the weight ratio between the one or more triglycerides and the one or more sweeteners is in the range of 1:50 to 1:4, and
ii) adding the one or more isolated cannabinoids in the sweetener powder composition before admixture with the one or more triglycerides.
2 . The method according to claim 1 , wherein the one or more triglycerides is selected from one or more C4 to C14 triglycerides.
3 . The method according to claim 1 , wherein the one or more triglycerides is selected from one or more C6 to C12 triglycerides.
4 . The method according to claim 1 , wherein the one or more triglycerides comprises a partially hydrogenated vegetable oil or a fully hydrogenated vegetable oil.
5 . The method according to claim 1 , wherein the one or more triglycerides is selected from triglycerides being liquid at or above 0 Degree Celsius.
6 . The method according to claim 1 , wherein the one or more triglycerides is a blend of a number of triglycerides.
7 . The method according to claim 1 , wherein the one or more triglycerides is heated to a temperature above ambient temperature before being added in the premixture.
8 . The method according to claim 1 , wherein the one or more triglycerides is heated to a temperature of 50 to 80 Degree Celsius before being added in the premixture.
9 . The method according to claim 1 , wherein the one or more triglycerides comprises caprylic acid in an amount of 50 to 80% by weight.
10 . The method according to claim 1 , wherein the one or more sweeteners is present in an amount of at least 50% by weight of the powder premixture.
11 . The method according to claim 1 , wherein the one or more sweeteners comprises one or more sugar alcohols selected from the group consisting of sorbitol, xylitol, maltitol, isomalt, mannitol, erythritol, lactitol, and combinations thereof.
12 . The method according to claim 1 , wherein the weight ratio between the one or more triglycerides and the one or more isolated cannabinoids is in the range of 1:40 to 1:1.
13 . The method according to claim 1 , wherein the one or more isolated cannabinoids is present in an amount of at least 5% by weight of the powder premixture.
14 . The method according to claim 1 , wherein the one or more isolated cannabinoids is selected from the group consisting of cannabidiol (CBD), cannabidiolic acid (CBDA), cannabidivarin (CBDV), and combinations thereof.
15 . The method according to claim 1 , wherein the one or more isolated cannabinoids is selected from the group consisting of tetrahydrocannabinol (THC), tetrahydrocannabinolic acid (THCA), tetrahydrocannabivarin (THCV), and combinations thereof.
16 . The method according to claim 1 , wherein the one or more isolated cannabinoids is present in a purity of at least 90% (w/w).
17 . The method according to claim 1 , wherein the premixture is a ready-to-use premixture.
18 . The method according to claim 1 , wherein the method comprises a step iii) of combining the premixture of step ii) in an amount of 10-99.9% by weight with further ingredients.
19 . A method of producing a powder premixture for oral administration of cannabinoids, the method comprising the steps of:
i) providing
a cannabinoid powder composition comprising one or more isolated cannabinoids in an amount of at least 2% by weight of the powder premixture;
a lipid composition consisting of one or more triglycerides in an amount of at least 1.0% by weight of the powder premixture; and
a sweetener powder composition comprising one or more sweeteners,
wherein the weight ratio between the one or more triglycerides and the one or more sweeteners is in the range of 1:50 to 1:4, and
ii) dissolving the one or more isolated cannabinoids in the one or more triglycerides before admixture with the sweetener powder composition.
20 . The method according to claim 19 , wherein the method comprises a step iii) of combining the premixture of step ii) in an amount of 10-99.9% by weight with further ingredients.
21 . A method of producing a powder premixture for oral administration of cannabinoids, the method comprising the steps of:
i) providing
a cannabinoid powder composition comprising one or more isolated cannabinoids in an amount of at least 2% by weight of the powder premixture;
a lipid composition consisting of one or more triglycerides in an amount of at least 1.0% by weight of the powder premixture; and
a sweetener powder composition comprising one or more sweeteners,
wherein the weight ratio between the one or more triglycerides and the one or more sweeteners is in the range of 1:50 to 1:4, and
ii) adding the one or more triglycerides in the sweetener powder composition before admixture with the one or more isolated cannabinoids.
22 . The method according to claim 21 , wherein the method comprises a step iii) of combining the premixture of step ii) in an amount of 10-99.9% by weight with further ingredients.