IP Library Granted Patent US 12697042
Granted Patent B2
US 12697042 · App. 18/927,760 · Granted Aug 4, 2026

System and methods for correct navigation of an instrument inside a human body

Inventor: Animesh Agarwal (San Francisco, CA)
Assignee: Anumana, Inc.
A61B5/068A61B5/062A61B5/7267A61B2018/00351A61B2018/00577A61B18/1492A61B2562/0223
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Quick Facts
Patent No.
US 12697042
App. No.
18/927,760
Granted
Aug 4, 2026
Kind
B2
Abstract

A system for correct navigation of an instrument inside a human body, comprising a reference instrument disposed at a first region of an anatomical part, a roving instrument disposed at a second region of the anatomical part, and a control circuit coupled with the reference instrument and the roving instrument, configured to receive a plurality of magnetic locations and a plurality of first impedance locations from the reference instrument, generate a localization model as a function of the plurality of magnetic locations and the plurality of first impedance locations, receive a second impedance location from the roving instrument, and generate an updated second impedance location of the roving instrument, using the localization model, as a function of the second impedance location.

Claims (49)

1 . A system for correct navigation of an instrument inside a human body, wherein the system comprises:

a reference instrument disposed at a first region of an anatomical part;

a roving instrument disposed at a second region of the anatomical part; and

a control circuit communicatively connected to the reference instrument and the roving instrument, wherein the control circuit comprises:

at least a processor and a memory communicatively connected to the at least a processor, wherein the memory contains instructions configuring the at least a processor to:

receive a plurality of ground truth locations and a plurality of first impedance locations from the reference instrument, wherein receiving the plurality of ground truth locations and the plurality of first impedance locations comprises moving the reference instrument within the first region of the anatomical part;

receive a second impedance location from the roving instrument; and

generate an updated second impedance location of the roving instrument as a function of the second impedance location, the plurality of ground truth locations, and the plurality of first impedance locations.

2 . The system of claim 1 , wherein:

the reference instrument comprises at least one magnetic sensor and a first impedance sensor, wherein the first impedance sensor comprises one or more pairs of surface electrodes attached to the reference instrument; and

the roving instrument comprises a second impedance sensor, wherein the second impedance sensor comprises one or more pairs of surface electrodes attached to the roving instrument.

3 . The system of claim 1 , wherein the memory contains instructions further configuring the at least a processor to order each of the plurality of ground truth locations and the plurality of first impedance locations in time order as a function of associated timestamps.

4 . The system of claim 1 , wherein receiving the plurality of ground truth locations and the plurality of first impedance locations comprises determining the first region within the anatomical part as a function of characteristics of the anatomical part and an objective of a procedure.

5 . The system of claim 1 , wherein the plurality of ground truth locations comprises ground truth location and the plurality of first impedance locations comprises corresponding input variables.

6 . The system of claim 1 , wherein moving the reference instrument comprises instructing the reference instrument to move within the first region using a pattern.

7 . The system of claim 6 , wherein the memory contains instructions further configuring the at least a processor to:

determine a drift as a function of the plurality of ground truth locations, the plurality of first impedance locations, and the pattern; and

initiate a recalibration process as a function of the drift.

8 . The system of claim 1 , wherein receiving the plurality of ground truth locations, the plurality of first impedance locations and the second impedance location comprises:

determining a displacement range between the reference instrument and the roving instrument as a function of a size of the anatomical part; and

receiving the plurality of ground truth locations, the plurality of first impedance locations and the second impedance location when the reference instrument and the roving instrument are within the displacement range.

9 . The system of claim 1 , wherein the memory contains instructions further configuring the at least a processor to:

construct a three-dimensional (3D) map of the first region and the second region;

highlight the updated second impedance location on the 3D map; and

display the 3D map on a display device.

10 . The system of claim 9 , wherein displaying the 3D map comprises displaying a depth of insertion of the roving instrument.

11 . A method for correct navigation of an instrument inside a human body, wherein the method comprises:

receiving, by a control circuit, a plurality of ground truth locations and a plurality of first impedance locations from a reference instrument disposed at a first region of an anatomical part, wherein receiving the plurality of ground truth locations, and the plurality of first impedance locations comprises moving the reference instrument within the first region of the anatomical part;

receiving, by the control circuit, a second impedance location from a roving instrument disposed at a second region of the anatomical part; and

generating, by the control circuit, an updated second impedance location of the roving instrument as a function of the plurality of ground truth locations, the plurality of first impedance locations and the second impedance location.

12 . The method of claim 11 , wherein:

the reference instrument comprises at least one magnetic sensor and a first impedance sensor, wherein the first impedance sensor comprises one or more pairs of surface electrodes attached to the reference instrument; and

the roving instrument comprises a second impedance sensor, wherein the second impedance sensor comprises one or more pairs of surface electrodes attached to the roving instrument.

13 . The method of claim 11 , further comprising:

ordering, by the control circuit, each of the plurality of ground truth locations and the plurality of first impedance locations in time order as a function of associated timestamps.

14 . The method of claim 11 , wherein receiving the plurality of ground truth locations and the plurality of first impedance locations comprises determining the first region within the anatomical part as a function of characteristics of the anatomical part and an objective of a procedure.

15 . The method of claim 11 , wherein the plurality of ground truth locations comprises ground truth location and the plurality of first impedance locations comprises corresponding input variables.

16 . The method of claim 11 , wherein moving the reference instrument comprises instructing the reference instrument to move within the first region using a pattern.

17 . The method of claim 16 , further comprising:

determine a drift as a function of the plurality of ground truth locations, the plurality of first impedance locations and the pattern; and

initiate a recalibration process as a function of the drift.

18 . The method of claim 11 , wherein receiving the plurality of ground truth locations, the plurality of first impedance locations and the second impedance location comprises:

determining a displacement range between the reference instrument and the roving instrument as a function of a size of the anatomical part; and

receiving the plurality of ground truth locations, the plurality of first impedance locations and the second impedance location when the reference instrument and the roving instrument are within the displacement range.

19 . The method of claim 11 , further comprising:

constructing, using the control circuit, a three-dimensional (3D) map of the first region and the second region;

highlighting, using the control circuit, the updated second impedance location on the 3D map; and

displaying, using the control circuit, the 3D map on a display device.

20 . The method of claim 19 , wherein displaying the 3D map comprises displaying a depth of insertion of the roving instrument.